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Title: Lasers for Medicine Final Report CRADA No. TC-0436-93

Abstract

This project is intended to advance the US position in laser diae~osis and treatment of disease in three thrust areas. A first laser system will advance the US position in photodynamic therapy whereby dyes are introduced into selected tissue and laser treatment with wavelena@ matching the dyes’ absorption band allows treatment of only the desired tissue. This effort will focus on the development and application of diode arrays delivering up to 10 watts at wavelengths of 657 nm, 675 nm and 695 nm with fiber optic delivery systems. This system would replace existing cumbersome systems with a compact diode array system. A second laser system is intended to advance the US position in the medical use of lasers in dermatology to remove port wine stains. The project will involve the development of a new all solid-state laser system to deliver light at 585 nm for the d~ect removal of port wine stains in human skin. This solid-state system would replace the currently used dye laser system with a compact, more efficient, less costly, environmentally benign solid-state laser system. Additionally this new laser system will offer new flexibility in the pulse format allowing treatment on a wider range of patients. Amore » third laser system is targeted to develop a diode-pumped TrnYAG laser system operating at 1.9 pm to drill small holes in animal eggs with the goal of improving fertility. This system would replace the current excimer system at 308 nm, which has undesirable mutagenic problems« less

Authors:
 [1];  [2]
  1. Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
  2. Beckman Laser Inst. and Medical Center, Irvine, CA (United States)
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1430936
Report Number(s):
LLNL-TR-747879
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
42 ENGINEERING; 59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Beach, R., and Berns, M. W. Lasers for Medicine Final Report CRADA No. TC-0436-93. United States: N. p., 2018. Web. doi:10.2172/1430936.
Beach, R., & Berns, M. W. Lasers for Medicine Final Report CRADA No. TC-0436-93. United States. doi:10.2172/1430936.
Beach, R., and Berns, M. W. Tue . "Lasers for Medicine Final Report CRADA No. TC-0436-93". United States. doi:10.2172/1430936. https://www.osti.gov/servlets/purl/1430936.
@article{osti_1430936,
title = {Lasers for Medicine Final Report CRADA No. TC-0436-93},
author = {Beach, R. and Berns, M. W.},
abstractNote = {This project is intended to advance the US position in laser diae~osis and treatment of disease in three thrust areas. A first laser system will advance the US position in photodynamic therapy whereby dyes are introduced into selected tissue and laser treatment with wavelena@ matching the dyes’ absorption band allows treatment of only the desired tissue. This effort will focus on the development and application of diode arrays delivering up to 10 watts at wavelengths of 657 nm, 675 nm and 695 nm with fiber optic delivery systems. This system would replace existing cumbersome systems with a compact diode array system. A second laser system is intended to advance the US position in the medical use of lasers in dermatology to remove port wine stains. The project will involve the development of a new all solid-state laser system to deliver light at 585 nm for the d~ect removal of port wine stains in human skin. This solid-state system would replace the currently used dye laser system with a compact, more efficient, less costly, environmentally benign solid-state laser system. Additionally this new laser system will offer new flexibility in the pulse format allowing treatment on a wider range of patients. A third laser system is targeted to develop a diode-pumped TrnYAG laser system operating at 1.9 pm to drill small holes in animal eggs with the goal of improving fertility. This system would replace the current excimer system at 308 nm, which has undesirable mutagenic problems},
doi = {10.2172/1430936},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 13 00:00:00 EDT 2018},
month = {Tue Mar 13 00:00:00 EDT 2018}
}

Technical Report:

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