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Title: Biological production of organic compounds

Patent ·
OSTI ID:1426794
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Methods of producing ethylene oxide and ethylene glycol are disclosed herein. Ethylene produced by cyanobacteria engineered to express ethylene-forming enzymes may be converted to ethylene oxide by bacteria engineered to express a monooxygenase enzyme. Ethylene oxide may be converted to ethylene glycol by exposure to an acidic solution. The methods may be performed in a bioreactor.

Research Organization:
National Renewable Energy Laboratory (NREL), Golden, CO (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC36-08GO28308
Assignee:
Alliance for Sustainable Energy, LLC (Golden, CO)
Patent Number(s):
9,914,947
Application Number:
15/054,868
OSTI ID:
1426794
Resource Relation:
Patent File Date: 2016 Feb 26
Country of Publication:
United States
Language:
English

References (38)

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DNA fragment comprising a gene encoding ethylene forming enzyme of bacteria and the use thereof patent July 1996
Ethanol production by microorganisms patent June 2011
Engineered CO2 fixing microorganisms producing carbon-based products of interest patent July 2011
Ethanol production in microorganisms patent November 2011
Selection of ADH in genetically modified cyanobacteria for the production of ethanol patent April 2012
Ethanol production in microorganisms patent July 2012
Engineered CO2 fixing microorganisms producing carbon-based products of interest patent July 2012
Ethanol production in microorganisms patent June 2013
Biological production of organic compounds patent April 2016
Genetically Modified Cyanobacteria for the Production of Ethanol patent-application March 2010
Modified Photosynthetic Microorganisms With Reduced Glycogen and Their Use in Producing Carbon-Based Products patent-application July 2010
Genetically Modified Photoautotrophic Ethanol Producing Host Cells, Method For Producing The Host Cells, Constructs For The Transformation Of The Host Cells, Method For Testing A Photoautotrophic Strain For A Desired Growth Property And Method Of Producing Ethanol Using The Host Cells patent-application November 2010
Molecular Approaches for the Optimization of Biofuel Production patent-application December 2010
Organisms for the Production of Isopropanol, N-Butanol, and Isobutanol patent-application December 2010
Designer Oxyphotobacteria and Greenhouse Distillation for Photobiological Ethanol Production from Carbon Dioxide and Water patent-application December 2010
Engineered CO2 Fixing Microorganisms Producing Carbon-Based Products of Interest patent-application January 2011
Modified Photosynthetic Microorganisms for Producing Lipids patent-application October 2011
Method for the Preparation of Diols patent-application December 2011
Microorganisms and Methods for the Production of Ethylene Glycol patent-application December 2011
Engineered CO2 Fixing Microorganisms Producing Carbon-Based Products of Interest patent-application May 2012
Biofuel From Recombinant Oleaginous Algae Using Sugar Carbon Sources patent-application June 2012
Genetically Engineered Cyanobacteria patent-application November 2012
Metabolically Engineered Organisms for the Production of Added Value Bio-Products patent-application May 2013
Biological Production of Organic Compounds patent-application August 2013
Biocatalytic conversion of ethylene to ethylene oxide using an engineered toluene monooxygenase journal January 2015
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Sucrose accumulation in salt-stressed cells of agp gene deletion-mutant in cyanobacterium Synechocystis sp. PCC 6803 journal January 2003
Photosynthetic conversion of carbon dioxide to ethylene by the recombinant cyanobacterium, Synechococcus sp. PCC 7942, which harbors a gene for the ethylene-forming enzyme of Pseudomonas syringae journal January 1997
Carbohydrate Metabolism in Mutants of the Cyanobacterium Synechococcus elongatus PCC 7942 Defective in Glycogen Synthesis journal April 2010
Construction and analysis of a recombinant cyanobacterium expressing a chromosomally inserted gene for an ethylene-forming enzyme at the psbAI locus journal January 2003
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Modification of carbon partitioning to enhance PHB production in Synechocystis sp. PCC6803 journal May 2002
Phosphoketolase pathway contributes to carbon metabolism in cyanobacteria journal December 2015

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59 BASIC BIOLOGICAL SCIENCES