skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: RCC2 is a novel p53 target in suppressing metastasis

Journal Article · · Oncogene
DOI:https://doi.org/10.1038/onc.2017.306· OSTI ID:1423348

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
FOREIGN
OSTI ID:
1423348
Journal Information:
Oncogene, Vol. 37, Issue 1; ISSN 0950-9232
Publisher:
Nature Publishing Group
Country of Publication:
United States
Language:
ENGLISH

References (39)

Structural Basis for Guanine Nucleotide Exchange on Ran by the Regulator of Chromosome Condensation (RCC1) journal April 2001
Rho GTPases in cancer cell biology journal May 2008
A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome journal January 2006
RAC1P29S is a spontaneously activating cancer-associated GTPase journal January 2013
A novel form of Epstein-Barr virus latency in normal B cells in vivo journal February 1995
Arp2/3 Is Critical for Lamellipodia and Response to Extracellular Matrix Cues but Is Dispensable for Chemotaxis journal March 2012
RNF43 is frequently mutated in colorectal and endometrial cancers journal October 2014
Comprehensive molecular characterization of human colon and rectal cancer journal July 2012
Modes of p53 Regulation journal May 2009
PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression journal April 2003
Contribution of p53 to Metastasis journal March 2014
Centromeric Aurora-B Activation Requires TD-60, Microtubules, and Substrate Priming Phosphorylation journal January 2008
Spatiotemporal Feedback between Actomyosin and Focal-Adhesion Systems Optimizes Rapid Cell Migration journal June 2006
p19 Arf -p53 Tumor Suppressor Pathway Regulates Cell Motility by Suppression of Phosphoinositide 3-Kinase and Rac1 GTPase Activities journal February 2003
Mitogen-Activated Protein Kinase Phosphatase 2: A Novel Transcription Target of p53 in Apoptosis journal June 2006
LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues journal October 2014
Proteomic Analysis of Integrin-Associated Complexes Identifies RCC2 as a Dual Regulator of Rac1 and Arf6 journal September 2009
The 1.7 Å crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller journal March 1998
Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer journal April 2014
NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription journal September 2000
Transcriptional control of human p53-regulated genes journal May 2008
LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma journal June 2012
A Rac switch regulates random versus directionally persistent cell migration journal August 2005
Second-harmonic generation in collagen as a potential cancer diagnostic parameter journal January 2008
Modeling the Therapeutic Efficacy of p53 Restoration in Tumors journal December 2006
The Mammalian Passenger Protein TD-60 Is an RCC1 Family Member with an Essential Role in Prometaphase to Metaphase Progression journal August 2003
Regulator of Chromosome Condensation 2 Identifies High-Risk Patients within Both Major Phenotypes of Colorectal Cancer journal April 2015
p53 and its mutants in tumor cell migration and invasion journal January 2011
Identification of MARCKS, FLJ11383 and TAF1B as putative novel target genes in colorectal carcinomas with microsatellite instability journal July 2002
PTEN C-Terminal Deletion Causes Genomic Instability and Tumor Development journal March 2014
Rho GTPases and the Actin Cytoskeleton journal January 1998
The expression of the KAI1 gene, a tumor metastasis suppressor, is directly activated by p53 journal September 1998
Rac1 targeting suppresses p53 deficiency–mediated lymphomagenesis journal April 2010
Definition of a consensus binding site for p53 journal April 1992
Structure of RCC1 chromatin factor bound to the nucleosome core particle journal August 2010
Chromosomal passengers and the (aurora) ABCs of mitosis journal February 2001
Phaser crystallographic software journal July 2007
DUSP1 Is Controlled by p53 during the Cellular Response to Oxidative Stress journal March 2008
Global cancer statistics, 2012: Global Cancer Statistics, 2012 journal February 2015

Similar Records

Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging
Journal Article · Tue May 15 00:00:00 EDT 2012 · Toxicology and Applied Pharmacology · OSTI ID:1423348

Mangiferin, a novel nuclear factor kappa B-inducing kinase inhibitor, suppresses metastasis and tumor growth in a mouse metastatic melanoma model
Journal Article · Thu Sep 01 00:00:00 EDT 2016 · Toxicology and Applied Pharmacology · OSTI ID:1423348

MicroRNA-340 suppresses osteosarcoma tumor growth and metastasis by directly targeting ROCK1
Journal Article · Fri Aug 09 00:00:00 EDT 2013 · Biochemical and Biophysical Research Communications · OSTI ID:1423348

Related Subjects