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Title: Effective Labeling of Primary Somatic Stem Cells with BaTiO 3 Nanocrystals for Second Harmonic Generation Imaging

Authors:
 [1];  [1];  [2];  [3]; ORCiD logo [1]
  1. Department of Biosystems Science and Engineering (D-BSSE), Eidgenössische Technische Hochschule (ETH) Zurich, 4058 Basel Switzerland
  2. Department of Biomedicine, University of Basel, 4058 Basel Switzerland
  3. The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley CA 94720 USA
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1417707
Grant/Contract Number:
AC02-05CH11231
Resource Type:
Journal Article: Publisher's Accepted Manuscript
Journal Name:
Small
Additional Journal Information:
Related Information: CHORUS Timestamp: 2018-01-22 11:29:39; Journal ID: ISSN 1613-6810
Publisher:
Wiley Blackwell (John Wiley & Sons)
Country of Publication:
Germany
Language:
English

Citation Formats

Sugiyama, Nami, Sonay, Ali Y., Tussiwand, Roxanne, Cohen, Bruce E., and Pantazis, Periklis. Effective Labeling of Primary Somatic Stem Cells with BaTiO 3 Nanocrystals for Second Harmonic Generation Imaging. Germany: N. p., 2018. Web. doi:10.1002/smll.201703386.
Sugiyama, Nami, Sonay, Ali Y., Tussiwand, Roxanne, Cohen, Bruce E., & Pantazis, Periklis. Effective Labeling of Primary Somatic Stem Cells with BaTiO 3 Nanocrystals for Second Harmonic Generation Imaging. Germany. doi:10.1002/smll.201703386.
Sugiyama, Nami, Sonay, Ali Y., Tussiwand, Roxanne, Cohen, Bruce E., and Pantazis, Periklis. 2018. "Effective Labeling of Primary Somatic Stem Cells with BaTiO 3 Nanocrystals for Second Harmonic Generation Imaging". Germany. doi:10.1002/smll.201703386.
@article{osti_1417707,
title = {Effective Labeling of Primary Somatic Stem Cells with BaTiO 3 Nanocrystals for Second Harmonic Generation Imaging},
author = {Sugiyama, Nami and Sonay, Ali Y. and Tussiwand, Roxanne and Cohen, Bruce E. and Pantazis, Periklis},
abstractNote = {},
doi = {10.1002/smll.201703386},
journal = {Small},
number = ,
volume = ,
place = {Germany},
year = 2018,
month = 1
}

Journal Article:
Free Publicly Available Full Text
This content will become publicly available on January 22, 2019
Publisher's Accepted Manuscript

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  • The photo-induced enhancement of second harmonic generation, and the effect of nanocrystal shape and pump intensity on confined acoustic phonons in semiconductor nanocrystals, has been investigated with time-resolved scattering and absorption measurements. The second harmonic signal showed a sublinear increase of the second order susceptibility with respect to the pump pulse energy, indicating a reduction of the effective one-electron second-order nonlinearity with increasing electron-hole density in the nanocrystals. The coherent acoustic phonons in spherical and rod-shaped semiconductor nanocrystals were detected in a time-resolved absorption measurement. Both nanocrystal morphologies exhibited oscillatory modulation of the absorption cross section, the frequency of whichmore » corresponded to their coherent radial breathing modes. The amplitude of the oscillation also increased with the level of photoexcitation, suggesting an increase in the amplitude of the lattice displacement as well.« less
  • Glass ceramic composites were prepared by bulk crystallization of NaNbO{sub 3} in sodium niobium borate glasses. A homogeneous bulk crystallization of the NaNbO{sub 3} phase takes place during heat treatments that produces visible-near infrared transparent materials with {approx}30 nm NaNbO{sub 3} nanocrystallites. Upon thermal poling, a strong Na{sup +} depleted nonlinear optical thin layer is observed at the anode side that should induce a large internal static electric field. In addition, the {chi}{sup (2)} response of the poled glass ceramic composites increases from 0.2 up to 1.9 pm/V with the rate of crystallization. Two mechanisms may be considered: a puremore » structural {chi}{sup (2)} process connected with the occurrence of a spontaneous ferroelectric polarization or an increase of the {chi}{sup (3)} response of the nanocrystallites that enhances the electric field induced second harmonic generation process.« less
  • We present observations of optical second-harmonic generation (SHG) from silicon nanocrystals embedded in SiO{sub 2}. SHG sensitivity to Si/SiO{sub 2} interface states, charge on the nanocrystals, and particle density gradients is demonstrated. SHG is proven to be a powerful noncontact nondestructive diagnosis tool for characterization of Si-nanocrystal-based devices and materials.
  • We have used the inherent surface sensitivity of second-harmonic generation to develop an instrument for nonlinear optical microscopy of surfaces and interfaces. This optical technique is ideal for imaging nanometer-thick, chromophoric self-assembled monolayers (SAMs), which have been patterned using photolithographic techniques. In this paper, we demonstrate the application of second-harmonic generation microscopy to patterned SAMs of the noncentrosymmetric molecule calixarene and discuss the resolution and sensitivity limits of the technique. {copyright} {ital 1997 American Institute of Physics.}