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Title: Competitive cation binding to phosphatidylinositol-4,5-bisphosphate domains revealed by X-ray fluorescence

Abstract

Calcium ions bind strongly to PIP 2at physiological concentrations, leading to condensation and decreased effective charge for PIP 2. Calcium displaces the more numerous magnesium and potassium ions, but some potassium ions remain.

Authors:
 [1];  [2];  [3];  [4];  [2];  [5]
  1. Department of Chemistry and Biochemistry; Kent State University; Kent; USA
  2. Ames Laboratory and Department of Physics and Astronomy; Iowa State University; Ames; USA
  3. Department of Physics; Kent State University; Kent; USA
  4. X-ray Science Division; Advanced Photon Source; Argonne National Laboratory; Lemont; USA
  5. Department of Biological Sciences; Kent State University; Kent; USA
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22)
OSTI Identifier:
1415472
DOE Contract Number:  
AC02-06CH11357
Resource Type:
Journal Article
Resource Relation:
Journal Name: RSC Advances; Journal Volume: 5; Journal Issue: 129
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Graber, Z. T., Wang, W., Singh, G., Kuzmenko, I., Vaknin, D., and Kooijman, E. E. Competitive cation binding to phosphatidylinositol-4,5-bisphosphate domains revealed by X-ray fluorescence. United States: N. p., 2015. Web. doi:10.1039/c5ra19023a.
Graber, Z. T., Wang, W., Singh, G., Kuzmenko, I., Vaknin, D., & Kooijman, E. E. Competitive cation binding to phosphatidylinositol-4,5-bisphosphate domains revealed by X-ray fluorescence. United States. doi:10.1039/c5ra19023a.
Graber, Z. T., Wang, W., Singh, G., Kuzmenko, I., Vaknin, D., and Kooijman, E. E. Thu . "Competitive cation binding to phosphatidylinositol-4,5-bisphosphate domains revealed by X-ray fluorescence". United States. doi:10.1039/c5ra19023a.
@article{osti_1415472,
title = {Competitive cation binding to phosphatidylinositol-4,5-bisphosphate domains revealed by X-ray fluorescence},
author = {Graber, Z. T. and Wang, W. and Singh, G. and Kuzmenko, I. and Vaknin, D. and Kooijman, E. E.},
abstractNote = {Calcium ions bind strongly to PIP2at physiological concentrations, leading to condensation and decreased effective charge for PIP2. Calcium displaces the more numerous magnesium and potassium ions, but some potassium ions remain.},
doi = {10.1039/c5ra19023a},
journal = {RSC Advances},
number = 129,
volume = 5,
place = {United States},
year = {Thu Jan 01 00:00:00 EST 2015},
month = {Thu Jan 01 00:00:00 EST 2015}
}