Microplasma-based flowing atmospheric-pressure afterglow (FAPA) source for ambient desorption-ionization mass spectrometry

Zeiri, Offer M.; Storey, Andrew P.; Ray, Steven J.; Hieftje, Gary M.

doi:10.1016/j.aca.2016.10.042

Title: Microplasma-based flowing atmospheric-pressure afterglow (FAPA) source for ambient desorption-ionization mass spectrometry

Journal Article · Sun Nov 11 00:00:00 EST 2018 · Analytica Chimica Acta

DOI:https://doi.org/10.1016/j.aca.2016.10.042· OSTI ID:1421374

Zeiri, Offer M. ^[1]; Storey, Andrew P. ^[1]; Ray, Steven J. ^[1];

^[1]

Indiana University, Bloomington, IN (United States)

A new direct-current microplasma-based flowing atmospheric pressure afterglow (FAPA) source was developed for use in ambient desorption-ionization mass spectrometry. The annular-shaped microplasma is formed in helium between two concentric stainless-steel capillaries that are separated by an alumina tube. Current-voltage characterization of the source shows that this version of the FAPA operates in the normal glow-discharge regime. A glass surface placed in the path of the helium afterglow reaches temperatures of up to approximately 400 °C; the temperature varies with distance from the source and helium flow rate through the source. Solid, liquid, and vapor samples were examined by means of a timeof- flight mass spectrometer. Results suggest that ionization occurs mainly through protonation, with only a small amount of fragmentation and adduct formation. Here, the mass range of the source was shown to extend up to at least m/z 2722 for singly charged species. Limits of detection for several small organic molecules were in the sub-picomole range. Examination of competitive ionization revealed that signal suppression occurs only at high (mM) concentrations of competing substances.

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Research Organization:: Indiana Univ., Bloomington, IN (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES). Chemical Sciences, Geosciences & Biosciences Division; USDOE

Grant/Contract Number:: FG02-98ER14890; FG02-98ER 14890

OSTI ID:: 1421374

Alternate ID(s):: OSTI ID: 1411304

Journal Information:: Analytica Chimica Acta, Vol. 952, Issue C; ISSN 0003-2670

Publisher:: ElsevierCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 12 works

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