Advances and challenges in cryo ptychography at the Advanced Photon Source

Deng, J.; Vine, D. J.; Chen, S.; Nashed, Y. S.G.; Jin, Q.; Peterka, T.; Vogt, S.; Jacobsen, C.

doi:10.1063/1.4937524

Title: Advances and challenges in cryo ptychography at the Advanced Photon Source

Conference · Fri Jan 01 00:00:00 EST 2016

DOI:https://doi.org/10.1063/1.4937524· OSTI ID:1411032

Deng, J.; Vine, D. J.; Chen, S.; Nashed, Y. S.G.; Jin, Q.; Peterka, T.; Vogt, S.; Jacobsen, C.

Ptychography has emerged as a nondestructive tool to quantitatively study extended samples at a high spatial resolution.In this manuscript, we report on recent developments from our team. We have combined cryo ptychography and fluorescence microscopy to provide simultaneous views of ultrastructure and elemental composition, we have developed multi-GPU parallel computation to speed up ptychographic reconstructions, and we have implemented fly-scan ptychography to allow for faster data acquisition. We conclude with a discussion of future challenges in high-resolution 3D ptychography.

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Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES); National Institutes of Health (NIH) - National Institute of General Medical Sciences

DOE Contract Number:: AC02-06CH11357

OSTI ID:: 1411032

Resource Relation:: Conference: 12th International Conference on X-Ray Microscopy , 10/26/14 - 10/31/14, Melbourne, Australia

Country of Publication:: United States

Language:: English

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