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Title: Engineering microorganisms to increase ethanol production by metabolic redirection

Abstract

The present invention provides for the manipulation of carbon flux in a recombinant host cell to increase the formation of desirable products. The invention relates to cellulose-digesting organisms that have been genetically modified to allow the production of ethanol at a high yield by redirecting carbon flux at key steps of central metabolism.

Inventors:
; ; ; ; ; ; ; ; ;
Publication Date:
Research Org.:
Enchi Corporation, Wellesley Hills, MA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1406573
Patent Number(s):
9,803,221
Application Number:
14/348,231
Assignee:
Enchi Corporation GFO
DOE Contract Number:
FC36-07GO17057; POS2-06ER64304
Resource Type:
Patent
Resource Relation:
Patent File Date: 2012 Sep 28
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 09 BIOMASS FUELS

Citation Formats

Deng, Yu, Olson, Daniel G., van Dijken, Johannes Pieter, Shaw, IV, Arthur J., Argyros, Aaron, Barrett, Trisha, Caiazza, Nicky, Herring, Christopher D., Rogers, Stephen R., and Agbogbo, Frank. Engineering microorganisms to increase ethanol production by metabolic redirection. United States: N. p., 2017. Web.
Deng, Yu, Olson, Daniel G., van Dijken, Johannes Pieter, Shaw, IV, Arthur J., Argyros, Aaron, Barrett, Trisha, Caiazza, Nicky, Herring, Christopher D., Rogers, Stephen R., & Agbogbo, Frank. Engineering microorganisms to increase ethanol production by metabolic redirection. United States.
Deng, Yu, Olson, Daniel G., van Dijken, Johannes Pieter, Shaw, IV, Arthur J., Argyros, Aaron, Barrett, Trisha, Caiazza, Nicky, Herring, Christopher D., Rogers, Stephen R., and Agbogbo, Frank. Tue . "Engineering microorganisms to increase ethanol production by metabolic redirection". United States. doi:. https://www.osti.gov/servlets/purl/1406573.
@article{osti_1406573,
title = {Engineering microorganisms to increase ethanol production by metabolic redirection},
author = {Deng, Yu and Olson, Daniel G. and van Dijken, Johannes Pieter and Shaw, IV, Arthur J. and Argyros, Aaron and Barrett, Trisha and Caiazza, Nicky and Herring, Christopher D. and Rogers, Stephen R. and Agbogbo, Frank},
abstractNote = {The present invention provides for the manipulation of carbon flux in a recombinant host cell to increase the formation of desirable products. The invention relates to cellulose-digesting organisms that have been genetically modified to allow the production of ethanol at a high yield by redirecting carbon flux at key steps of central metabolism.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 31 00:00:00 EDT 2017},
month = {Tue Oct 31 00:00:00 EDT 2017}
}

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