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Title: Does irradiation enhance or inhibit strain bursts at the submicron scale?

Authors:
; ;
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1397864
Grant/Contract Number:
FG02-03ER54708
Resource Type:
Journal Article: Publisher's Accepted Manuscript
Journal Name:
Acta Materialia
Additional Journal Information:
Journal Volume: 132; Journal Issue: C; Related Information: CHORUS Timestamp: 2017-10-04 22:24:17; Journal ID: ISSN 1359-6454
Publisher:
Elsevier
Country of Publication:
United States
Language:
English

Citation Formats

Cui, Yinan, Po, Giacomo, and Ghoniem, Nasr. Does irradiation enhance or inhibit strain bursts at the submicron scale?. United States: N. p., 2017. Web. doi:10.1016/j.actamat.2017.04.055.
Cui, Yinan, Po, Giacomo, & Ghoniem, Nasr. Does irradiation enhance or inhibit strain bursts at the submicron scale?. United States. doi:10.1016/j.actamat.2017.04.055.
Cui, Yinan, Po, Giacomo, and Ghoniem, Nasr. Thu . "Does irradiation enhance or inhibit strain bursts at the submicron scale?". United States. doi:10.1016/j.actamat.2017.04.055.
@article{osti_1397864,
title = {Does irradiation enhance or inhibit strain bursts at the submicron scale?},
author = {Cui, Yinan and Po, Giacomo and Ghoniem, Nasr},
abstractNote = {},
doi = {10.1016/j.actamat.2017.04.055},
journal = {Acta Materialia},
number = C,
volume = 132,
place = {United States},
year = {Thu Jun 01 00:00:00 EDT 2017},
month = {Thu Jun 01 00:00:00 EDT 2017}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record at 10.1016/j.actamat.2017.04.055

Citation Metrics:
Cited by: 1work
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  • In an attempt to determine the relative importance of the nerve cell body and of the axon in initiating and controlling axonal regeneration, nerve cell bodies were irradiated and the ability of the distal axon to sprout was examined. Mice were subjected to either 25 or 50 Gray (Gy) of x-irradiation localized to the lumbar spinal cord. After times varying from 1 day to 6 months after irradiation, a sublethal dose of botulinum toxin (BoTx) was injected into the calf muscles of one leg. The soleus muscle was examined histologically after times varying from 1 week to 6 months aftermore » injection, and BoTx-induced ultraterminal axonal sprouting was assessed by the number of motor endplates showing sprouts, the length of the sprouts, and the long term endplate morphology. Apart from some irradiated subgroups having slightly shorter sprout lengths, no significant differences were found between irradiated and nonirradiated groups. The results suggest either that the processes in the nerve cell body responsible for initiating and supporting axonal growth are resistant to large doses of irradiation, or that growth regulatory mechanisms in the distal axon are under local control.« less
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