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Title: Reversible Gene Drive Mechanism Utilizing Trana Inactivating Paramutatlons In Insects (paramutale 0.9)

Abstract

The paramutate software package Is a tool to calculate the genotyplc and phenotyplc propagation of a gene drive that can be silenced with a homologuus trans-Inactivating panmutatlon, ln dlptera or other species with a slmUar-acttng pl RNA system/Plwi pathway. Method of SolaUon: paramutate uses rults of Mendelian, gene drive (I.e.. stimulated conversion), and maternal Inheritance to compute the propaptlon of a notional gene drive construct and Its trans-lnactlvat1n1 paramutatlon, throu1b a panmlctlc, fixed-size population reproducing In synchronous generations.

Authors:
 [1]
  1. LLNL
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE National Nuclear Security Administration (NNSA)
Contributing Org.:
Lawrence Livermore National Laboratory
OSTI Identifier:
1395234
Report Number(s):
Reversible Gene Drive Mechanism Utilizing Trana­ I; 005447WKSTN00
LLNL-CODE-738986
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Software
Software Revision:
00
Software Package Number:
005447
Software CPU:
WKSTN
Open Source:
Yes
Source Code Available:
Yes
Country of Publication:
United States

Citation Formats

Drocco, Jeffery A. Reversible Gene Drive Mechanism Utilizing Trana Inactivating Paramutatlons In Insects (paramutale 0.9). Computer software. https://www.osti.gov//servlets/purl/1395234. Vers. 00. USDOE National Nuclear Security Administration (NNSA). 6 Sep. 2017. Web.
Drocco, Jeffery A. (2017, September 6). Reversible Gene Drive Mechanism Utilizing Trana Inactivating Paramutatlons In Insects (paramutale 0.9) (Version 00) [Computer software]. https://www.osti.gov//servlets/purl/1395234.
Drocco, Jeffery A. Reversible Gene Drive Mechanism Utilizing Trana Inactivating Paramutatlons In Insects (paramutale 0.9). Computer software. Version 00. September 6, 2017. https://www.osti.gov//servlets/purl/1395234.
@misc{osti_1395234,
title = {Reversible Gene Drive Mechanism Utilizing Trana Inactivating Paramutatlons In Insects (paramutale 0.9), Version 00},
author = {Drocco, Jeffery A.},
abstractNote = {The paramutate software package Is a tool to calculate the genotyplc and phenotyplc propagation of a gene drive that can be silenced with a homologuus trans-Inactivating panmutatlon, ln dlptera or other species with a slmUar-acttng pl RNA system/Plwi pathway. Method of SolaUon: paramutate uses rults of Mendelian, gene drive (I.e.. stimulated conversion), and maternal Inheritance to compute the propaptlon of a notional gene drive construct and Its trans-lnactlvat1n1 paramutatlon, throu1b a panmlctlc, fixed-size population reproducing In synchronous generations.},
url = {https://www.osti.gov//servlets/purl/1395234},
doi = {},
year = {Wed Sep 06 00:00:00 EDT 2017},
month = {Wed Sep 06 00:00:00 EDT 2017},
note =
}

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