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Title: Polyvinylpyrrolidone (PVP)-Capped Pt Nanocubes with Superior Peroxidase-Like Activity

Abstract

Peroxidase mimics of inorganic nanoparticles are expected to circumvent the inherent issues of natural peroxidases, providing enhanced performance in important applications such as diagnosis and imaging. Despite the report of a variety of peroxidase mimics in the past decade, very limited progress has been made on improving their catalytic efficiency. The catalytic efficiencies of most previously reported mimics are only up to one order of magnitude higher than those of natural peroxidases. In this work, we demonstrate a type of highly efficient peroxidase mimic – polyvinylpyrrolidone (PVP)-capped Pt nanocubes of sub-10 nm in size. These PVP-capped Pt cubes are ~200-fold more active than the natural counterparts and exhibit a record-high specific catalytic efficiency. In addition to the superior efficiency, the new mimic shows several other promising features, including excellent stabilities, well-controlled uniformity in both size and shape, controllable sizes, and facile and scalable production.

Authors:
 [1];  [2];  [1];  [1];  [1]
  1. Department of Chemistry, Michigan Technological University, Houghton Michigan 49931 United States
  2. Center for Nanoscale Materials, Argonne National Laboratory, Argonne Illinois 60439 United States
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE Office of Science - Office of Basic Energy Sciences - Scientific User Facilities Division
OSTI Identifier:
1389648
DOE Contract Number:  
AC02-06CH11357
Resource Type:
Journal Article
Journal Name:
ChemNanoMat
Additional Journal Information:
Journal Volume: 3; Journal Issue: 1; Journal ID: ISSN 2199-692X
Publisher:
Wiley
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 36 MATERIALS SCIENCE

Citation Formats

Ye, Haihang, Liu, Yuzi, Chhabra, Ashima, Lilla, Emily, and Xia, Xiaohu. Polyvinylpyrrolidone (PVP)-Capped Pt Nanocubes with Superior Peroxidase-Like Activity. United States: N. p., 2016. Web. doi:10.1002/cnma.201600268.
Ye, Haihang, Liu, Yuzi, Chhabra, Ashima, Lilla, Emily, & Xia, Xiaohu. Polyvinylpyrrolidone (PVP)-Capped Pt Nanocubes with Superior Peroxidase-Like Activity. United States. doi:10.1002/cnma.201600268.
Ye, Haihang, Liu, Yuzi, Chhabra, Ashima, Lilla, Emily, and Xia, Xiaohu. Wed . "Polyvinylpyrrolidone (PVP)-Capped Pt Nanocubes with Superior Peroxidase-Like Activity". United States. doi:10.1002/cnma.201600268.
@article{osti_1389648,
title = {Polyvinylpyrrolidone (PVP)-Capped Pt Nanocubes with Superior Peroxidase-Like Activity},
author = {Ye, Haihang and Liu, Yuzi and Chhabra, Ashima and Lilla, Emily and Xia, Xiaohu},
abstractNote = {Peroxidase mimics of inorganic nanoparticles are expected to circumvent the inherent issues of natural peroxidases, providing enhanced performance in important applications such as diagnosis and imaging. Despite the report of a variety of peroxidase mimics in the past decade, very limited progress has been made on improving their catalytic efficiency. The catalytic efficiencies of most previously reported mimics are only up to one order of magnitude higher than those of natural peroxidases. In this work, we demonstrate a type of highly efficient peroxidase mimic – polyvinylpyrrolidone (PVP)-capped Pt nanocubes of sub-10 nm in size. These PVP-capped Pt cubes are ~200-fold more active than the natural counterparts and exhibit a record-high specific catalytic efficiency. In addition to the superior efficiency, the new mimic shows several other promising features, including excellent stabilities, well-controlled uniformity in both size and shape, controllable sizes, and facile and scalable production.},
doi = {10.1002/cnma.201600268},
journal = {ChemNanoMat},
issn = {2199-692X},
number = 1,
volume = 3,
place = {United States},
year = {2016},
month = {12}
}

Works referenced in this record:

Quantitative Analysis of the Role Played by Poly(vinylpyrrolidone) in Seed-Mediated Growth of Ag Nanocrystals
journal, January 2012

  • Xia, Xiaohu; Zeng, Jie; Oetjen, L. Kyle
  • Journal of the American Chemical Society, Vol. 134, Issue 3
  • DOI: 10.1021/ja210047e

Morphological Control of Catalytically Active Platinum Nanocrystals
journal, November 2006

  • Lee, Hyunjoo; Habas, Susan E.; Kweskin, Sasha
  • Angewandte Chemie International Edition, Vol. 45, Issue 46, p. 7824-7828
  • DOI: 10.1002/anie.200603068

Synthesis of Monodisperse Pt Nanocubes and Their Enhanced Catalysis for Oxygen Reduction
journal, June 2007

  • Wang, Chao; Daimon, Hideo; Lee, Youngmin
  • Journal of the American Chemical Society, Vol. 129, Issue 22
  • DOI: 10.1021/ja070440r

Platinum Nanoparticle Shape Effects on Benzene Hydrogenation Selectivity
journal, October 2007

  • Bratlie, Kaitlin M.; Lee, Hyunjoo; Komvopoulos, Kyriakos
  • Nano Letters, Vol. 7, Issue 10
  • DOI: 10.1021/nl0716000

How Structure-Directing Agents Control Nanocrystal Shape: Polyvinylpyrrolidone-Mediated Growth of Ag Nanocubes
journal, October 2015


Quantitative Analysis of the Coverage Density of Br Ions on Pd{100} Facets and Its Role in Controlling the Shape of Pd Nanocrystals
journal, March 2013

  • Peng, Hsin-Chieh; Xie, Shuifen; Park, Jinho
  • Journal of the American Chemical Society, Vol. 135, Issue 10
  • DOI: 10.1021/ja400301k

Sum Frequency Generation and Catalytic Reaction Studies of the Removal of Organic Capping Agents from Pt Nanoparticles by UV−Ozone Treatment
journal, February 2009

  • Aliaga, Cesar; Park, Jeong Y.; Yamada, Yusuke
  • The Journal of Physical Chemistry C, Vol. 113, Issue 15, p. 6150-6155
  • DOI: 10.1021/jp8108946

The Determination of Enzyme Dissociation Constants
journal, March 1934

  • Lineweaver, Hans; Burk, Dean
  • Journal of the American Chemical Society, Vol. 56, Issue 3
  • DOI: 10.1021/ja01318a036

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
journal, January 2013

  • Wei, Hui; Wang, Erkang
  • Chemical Society Reviews, Vol. 42, Issue 14
  • DOI: 10.1039/c3cs35486e

Pd–Ir Core–Shell Nanocubes: A Type of Highly Efficient and Versatile Peroxidase Mimic
journal, September 2015


Morphological Control of Catalytically Active Platinum Nanocrystals
journal, November 2006

  • Lee, Hyunjoo; Habas, Susan E.; Kweskin, Sasha
  • Angewandte Chemie, Vol. 118, Issue 46
  • DOI: 10.1002/ange.200603068

Recent Developments in Shape-Controlled Synthesis of Silver Nanocrystals
journal, September 2012

  • Xia, Xiaohu; Zeng, Jie; Zhang, Qiang
  • The Journal of Physical Chemistry C, Vol. 116, Issue 41
  • DOI: 10.1021/jp306063p

On the role of surface diffusion in determining the shape or morphology of noble-metal nanocrystals
journal, April 2013

  • Xia, X.; Xie, S.; Liu, M.
  • Proceedings of the National Academy of Sciences, Vol. 110, Issue 17
  • DOI: 10.1073/pnas.1222109110

Enzyme Immunoassay (EIA)/Enzyme-Linked Immunosorbent Assay (ELISA)
journal, December 2005


Shape-Controlled Synthesis of Colloidal Metal Nanocrystals: Thermodynamic versus Kinetic Products
journal, June 2015

  • Xia, Younan; Xia, Xiaohu; Peng, Hsin-Chieh
  • Journal of the American Chemical Society, Vol. 137, Issue 25
  • DOI: 10.1021/jacs.5b04641