Simulations of cellulose translocation in the bacterial cellulose synthase suggest a regulatory mechanism for the dimeric structure of cellulose

Knott, Brandon C.; Crowley, Michael F.; Himmel, Michael E.; Zimmer, Jochen; Beckham, Gregg T.

doi:10.1039/C5SC04558D

Title: Simulations of cellulose translocation in the bacterial cellulose synthase suggest a regulatory mechanism for the dimeric structure of cellulose

Journal Article · Fri Jan 01 00:00:00 EST 2016 · Chemical Science

DOI:https://doi.org/10.1039/C5SC04558D· OSTI ID:1388828

Knott, Brandon C. ^[1]; Crowley, Michael F. ^[2]; Himmel, Michael E. ^[2]; Zimmer, Jochen ^[3]; Beckham, Gregg T. ^[1]

National Bioenergy Center; National Renewable Energy Laboratory; Golden CO 80401; USA
Biosciences Center; National Renewable Energy Laboratory; Golden CO 80401; USA
Center for Membrane Biology; Department of Molecular Physiology and Biological Physics; University of Virginia; Charlottesville; USA

In addition to suggesting a mechanism for regulating cellulose structure, molecular simulations indicate translocation is not rate-limiting for cellulose biosynthesis.

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Research Organization:: Energy Frontier Research Centers (EFRC) (United States). Center for Direct Catalytic Conversion of Biomass to Biofuels (C3Bio)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

DOE Contract Number:: SC000997

OSTI ID:: 1388828

Journal Information:: Chemical Science, Vol. 7, Issue 5; Related Information: C3Bio partners with Purdue University (lead); Argonne National Laboratory; National Renewable Energy Laboratory; Northeastern University; University of Tennessee; ISSN 2041-6520

Publisher:: Royal Society of Chemistry

Country of Publication:: United States

Language:: English

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