Next-generation in vivo optical imaging with short-wave infrared quantum dots

Bruns, Oliver T.; Bischof, Thomas S.; Harris, Daniel K.; Franke, Daniel; Shi, Yanxiang; Riedemann, Lars; Bartelt, Alexander; Jaworski, Frank B.; Carr, Jessica A.; Rowlands, Christopher J.; Wilson, Mark W.  B.; Chen, Ou; Wei, He; Hwang, Gyu Weon; Montana, Daniel M.; Coropceanu, Igor; Achorn, Odin B.; Kloepper, Jonas; Heeren, Joerg; So, Peter T.  C.; Fukumura, Dai; Jensen, Klavs F.; Jain, Rakesh K.; Bawendi, Moungi G.

doi:10.1038/s41551-017-0056

Title: Next-generation in vivo optical imaging with short-wave infrared quantum dots

Journal Article · Mon Apr 10 00:00:00 EDT 2017 · Nature Biomedical Engineering (Online)

DOI:https://doi.org/10.1038/s41551-017-0056· OSTI ID:1388341

;

; Harris, Daniel K.; Franke, Daniel; Shi, Yanxiang; Riedemann, Lars; Bartelt, Alexander; Jaworski, Frank B.;

; Rowlands, Christopher J.;

; Chen, Ou; Wei, He;

; Montana, Daniel M.; Coropceanu, Igor; Achorn, Odin B.; Kloepper, Jonas;

; So, Peter T. C. more »

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Research Organization:: Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES); USDOD; National Institutes of Health (NIH); National Foundation for Cancer Research (NFCR); Massachusetts General Hospital, Boston, MA (United States); US Army Research Office (ARO); National Science Foundation (NSF); European Molecular Biology Organization (EMBO); German Research Foundation (DFG); Evonik Foundation; Boehringer Ingelheim Fonds (BIF); Leducq Foundation; German Cancer Aid; Solidar-Immun Foundation; Hamamatsu Photonics (Japan); SAMSUNG Global Research Outreach (GRO) Program

DOE Contract Number:: SC0001088; 5-U54-CA151884; P01-CA080124; R35 CA197743; P50 CA165962; R01-CA126642; R01-CA096915; 4-P41-EB015871-30; W911NF-13-D-0001; W81XWH-10-1-0016; ECCS-1449291; BA 4925/1-1; 32 CFR 168a; DP3-DK101024 01; 1-U01-NS090438-01; 1-R01-EY017656-0, 6A1; 1-R01-HL121386-01A1

OSTI ID:: 1388341

Journal Information:: Nature Biomedical Engineering (Online), Vol. 1, Issue 4; Related Information: CE partners with Massachusetts Institute of Technology (lead); Brookhaven National Laboratory; Harvard University; ISSN 2157-846X

Country of Publication:: United States

Language:: English

References (47)

Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival Kloepper, Jonas; Riedemann, Lars; Amoozgar, Zohreh Proceedings of the National Academy of Sciences, Vol. 113, Issue 16 https://doi.org/10.1073/pnas.1525360113	journal	April 2016
Biodistribution, pharmacokinetics and toxicology of Ag2S near-infrared quantum dots in mice Zhang, Yan; Zhang, Yejun; Hong, Guosong Biomaterials, Vol. 34, Issue 14 https://doi.org/10.1016/j.biomaterials.2013.01.089	journal	May 2013
Imaging preclinical tumour models: improving translational power de Jong, Marion; Essers, Jeroen; van Weerden, Wytske M. Nature Reviews Cancer, Vol. 14, Issue 7 https://doi.org/10.1038/nrc3751	journal	June 2014
Carbon nanotubes as in vivo bacterial probes Bardhan, Neelkanth M.; Ghosh, Debadyuti; Belcher, Angela M. Nature Communications, Vol. 5, Issue 1 https://doi.org/10.1038/ncomms5918	journal	September 2014
Selection of Quantum Dot Wavelengths for Biomedical Assays and Imaging Lim, Yong Taik; Kim, Sungjee; Nakayama, Akira Molecular Imaging, Vol. 2, Issue 1 https://doi.org/10.1162/153535003765276282	journal	January 2003
Compact high-quality CdSe–CdS core–shell nanocrystals with narrow emission linewidths and suppressed blinking Chen, Ou; Zhao, Jing; Chauhan, Vikash P. Nature Materials, Vol. 12, Issue 5 https://doi.org/10.1038/nmat3539	journal	February 2013
Colloidal PbS Nanocrystals with Size-Tunable Near-Infrared Emission: Observation of Post-Synthesis Self-Narrowing of the Particle Size Distribution Hines, M. A.; Scholes, G. D. Advanced Materials, Vol. 15, Issue 21, p. 1844-1849 https://doi.org/10.1002/adma.200305395	journal	November 2003
Real-time magnetic resonance imaging and quantification of lipoprotein metabolism in vivo using nanocrystals Bruns, Oliver T.; Ittrich, Harald; Peldschus, Kersten Nature Nanotechnology, Vol. 4, Issue 3 https://doi.org/10.1038/nnano.2008.405	journal	January 2009
Intraperitoneal Injection Improves the Uptake of Nanoparticle-Labeled High-Density Lipoprotein to Atherosclerotic Plaques Compared With Intravenous Injection: A Multimodal Imaging Study in ApoE Knockout Mice Jung, Caroline; Kaul, Michael G.; Bruns, Oliver T. Circulation: Cardiovascular Imaging, Vol. 7, Issue 2 https://doi.org/10.1161/CIRCIMAGING.113.000607	journal	March 2014
Particle-Imaging Techniques For Experimental Fluid-Mechanics Adrian, R. Annual Review of Fluid Mechanics, Vol. 23, Issue 1 https://doi.org/10.1146/annurev.fluid.23.1.261	journal	January 1991
All-optical anatomical co-registration for molecular imaging of small animals using dynamic contrast Hillman, Elizabeth M. C.; Moore, Anna Nature Photonics, Vol. 1, Issue 9 https://doi.org/10.1038/nphoton.2007.146	journal	August 2007
Twenty years of particle image velocimetry Adrian, R. J. Experiments in Fluids, Vol. 39, Issue 2 https://doi.org/10.1007/s00348-005-0991-7	journal	July 2005
A PIV Algorithm for Estimating Time-Averaged Velocity Fields Meinhart, Carl D.; Wereley, Steve T.; Santiago, Juan G. Journal of Fluids Engineering, Vol. 122, Issue 2 https://doi.org/10.1115/1.483256	journal	February 2000
Rare-earth-doped biological composites as in vivo shortwave infrared reporters Naczynski, D. J.; Tan, M. C.; Zevon, M. Nature Communications, Vol. 4, Issue 1 https://doi.org/10.1038/ncomms3199	journal	July 2013
Ag ₂ S Quantum Dot: A Bright and Biocompatible Fluorescent Nanoprobe in the Second Near-Infrared Window Zhang, Yan; Hong, Guosong; Zhang, Yejun ACS Nano, Vol. 6, Issue 5 https://doi.org/10.1021/nn301218z	journal	April 2012
Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo Stroh, Mark; Zimmer, John P.; Duda, Dan G. Nature Medicine, Vol. 11, Issue 6 https://doi.org/10.1038/nm1247	journal	May 2005
Fiji: an open-source platform for biological-image analysis Schindelin, Johannes; Arganda-Carreras, Ignacio; Frise, Erwin Nature Methods, Vol. 9, Issue 7 https://doi.org/10.1038/nmeth.2019	journal	June 2012
Nanocrystals, a New Tool to Study Lipoprotein Metabolism and Atherosclerosis Heeren, Joerg; Bruns, Oliver Current Pharmaceutical Biotechnology, Vol. 13, Issue 2 https://doi.org/10.2174/138920112799095293	journal	February 2012
Synthesis of InAs/CdSe/ZnSe Core/Shell1/Shell2 Structures with Bright and Stable Near-Infrared Fluorescence Aharoni, Assaf; Mokari, Taleb; Popov, Inna Journal of the American Chemical Society, Vol. 128, Issue 1 https://doi.org/10.1021/ja056326v	journal	January 2006
Deep-tissue anatomical imaging of mice using carbon nanotube fluorophores in the second near-infrared window Welsher, K.; Sherlock, S. P.; Dai, H. Proceedings of the National Academy of Sciences, Vol. 108, Issue 22 https://doi.org/10.1073/pnas.1014501108	journal	May 2011
Large-Scale Synthesis of Nearly Monodisperse CdSe/CdS Core/Shell Nanocrystals Using Air-Stable Reagents via Successive Ion Layer Adsorption and Reaction Li, J. Jack; Wang, Y. Andrew; Guo, Wenzhuo Journal of the American Chemical Society, Vol. 125, Issue 41, p. 12567-12575 https://doi.org/10.1021/ja0363563	journal	October 2003
Through-skull fluorescence imaging of the brain in a new near-infrared window Hong, Guosong; Diao, Shuo; Chang, Junlei Nature Photonics, Vol. 8, Issue 9 https://doi.org/10.1038/nphoton.2014.166	journal	August 2014
Synthesis and optical properties of emission-tunable PbS/CdS core–shell quantum dots for in vivo fluorescence imaging in the second near-infrared window Tsukasaki, Yoshikazu; Morimatsu, Masatoshi; Nishimura, Goro RSC Adv., Vol. 4, Issue 77 https://doi.org/10.1039/C4RA06098A	journal	January 2014
M13 Phage-Functionalized Single-Walled Carbon Nanotubes As Nanoprobes for Second Near-Infrared Window Fluorescence Imaging of Targeted Tumors Yi, Hyunjung; Ghosh, Debadyuti; Ham, Moon-Ho Nano Letters, Vol. 12, Issue 3 https://doi.org/10.1021/nl2031663	journal	February 2012
Biological Imaging Using Nanoparticles of Small Organic Molecules with Fluorescence Emission at Wavelengths Longer than 1000 nm Tao, Zhimin; Hong, Guosong; Shinji, Chihiro Angewandte Chemie International Edition, Vol. 52, Issue 49 https://doi.org/10.1002/anie.201307346	journal	October 2013
Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes Ghosh, D.; Bagley, A. F.; Na, Y. J. Proceedings of the National Academy of Sciences, Vol. 111, Issue 38 https://doi.org/10.1073/pnas.1400821111	journal	September 2014
A short-wavelength infrared emitting multimodal probe for non-invasive visualization of phagocyte cell migration in living mice Tsukasaki, Y.; Komatsuzaki, A.; Mori, Y. Chem. Commun., Vol. 50, Issue 92 https://doi.org/10.1039/C4CC06542E	journal	January 2014
High-Performance Shortwave-Infrared Light-Emitting Devices Using Core-Shell (PbS-CdS) Colloidal Quantum Dots Supran, Geoffrey J.; Song, Katherine W.; Hwang, Gyu Weon Advanced Materials, Vol. 27, Issue 8 https://doi.org/10.1002/adma.201404636	journal	January 2015
Blind Source Separation Techniques for the Decomposition of Multiply Labeled Fluorescence Images Neher, Richard A.; Mitkovski, Mišo; Kirchhoff, Frank Biophysical Journal, Vol. 96, Issue 9 https://doi.org/10.1016/j.bpj.2008.10.068	journal	May 2009
Comparison of Gaussian particle center estimators and the achievable measurement density for particle tracking velocimetry Marxen, M.; Sullivan, P. E.; Loewen, M. R. Experiments in Fluids, Vol. 29, Issue 2 https://doi.org/10.1007/s003489900085	journal	August 2000
A route to brightly fluorescent carbon nanotubes for near-infrared imaging in mice Welsher, Kevin; Liu, Zhuang; Sherlock, Sarah P. Nature Nanotechnology, Vol. 4, Issue 11 https://doi.org/10.1038/nnano.2009.294	journal	October 2009
Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in vascular networks Kamoun, Walid S.; Chae, Sung-Suk; Lacorre, Delphine A. Nature Methods, Vol. 7, Issue 8 https://doi.org/10.1038/nmeth.1475	journal	June 2010
Measurements of turbulence in a microscale multi-inlet vortex nanoprecipitation reactor Shi, Yanxiang; Cheng, Janine Chungyin; Fox, Rodney O. Journal of Micromechanics and Microengineering, Vol. 23, Issue 7 https://doi.org/10.1088/0960-1317/23/7/075005	journal	June 2013
Utilizing the Lability of Lead Selenide to Produce Heterostructured Nanocrystals with Bright, Stable Infrared Emission Pietryga, Jeffrey M.; Werder, Donald J.; Williams, Darrick J. Journal of the American Chemical Society, Vol. 130, Issue 14 https://doi.org/10.1021/ja710437r	journal	April 2008
Nanocrystal Core Lipoprotein Biomimetics for Imaging of Lipoproteins and Associated Diseases Fay, Francois; Sanchez-Gaytan, Brenda L.; Cormode, David P. Current Cardiovascular Imaging Reports, Vol. 6, Issue 1 https://doi.org/10.1007/s12410-012-9181-1	journal	December 2012
Multifunctional in vivo vascular imaging using near-infrared II fluorescence Hong, Guosong; Lee, Jerry C.; Robinson, Joshua T. Nature Medicine, Vol. 18, Issue 12 https://doi.org/10.1038/nm.2995	journal	November 2012
A secreted luciferase for ex vivo monitoring of in vivo processes Wurdinger, Thomas; Badr, Christian; Pike, Lisa Nature Methods, Vol. 5, Issue 2 https://doi.org/10.1038/nmeth.1177	journal	January 2008
In Vivo Imaging of Quantum Dots Encapsulated in Phospholipid Micelles Dubertret, B. Science, Vol. 298, Issue 5599 https://doi.org/10.1126/science.1077194	journal	November 2002
Retinal receptors in rodents maximally sensitive to ultraviolet light Jacobs, Gerald H.; Neitz, Jay; Deegan, Jess F. Nature, Vol. 353, Issue 6345 https://doi.org/10.1038/353655a0	journal	October 1991
Brown adipose tissue activity controls triglyceride clearance Bartelt, Alexander; Bruns, Oliver T.; Reimer, Rudolph Nature Medicine, Vol. 17, Issue 2 https://doi.org/10.1038/nm.2297	journal	January 2011
Facile Synthesis of Highly Photoluminescent Ag ₂ Se Quantum Dots as a New Fluorescent Probe in the Second Near-Infrared Window for in Vivo Imaging Dong, Bohua; Li, Chunyan; Chen, Guangcun Chemistry of Materials, Vol. 25, Issue 12 https://doi.org/10.1021/cm400812v	journal	June 2013
Continuous injection synthesis of indium arsenide quantum dots emissive in the short-wavelength infrared Franke, Daniel; Harris, Daniel K.; Chen, Ou Nature Communications, Vol. 7, Issue 1 https://doi.org/10.1038/ncomms12749	journal	November 2016
Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases Kodack, D. P.; Chung, E.; Yamashita, H. Proceedings of the National Academy of Sciences, Vol. 109, Issue 45 https://doi.org/10.1073/pnas.1216078109	journal	October 2012
Ultrafast fluorescence imaging in vivo with conjugated polymer fluorophores in the second near-infrared window Hong, Guosong; Zou, Yingping; Antaris, Alexander L. Nature Communications, Vol. 5, Issue 1 https://doi.org/10.1038/ncomms5206	journal	June 2014
Particle-Imaging Techniques for Experimental Fluid Mechanics Adrian, Ronald J. Annual Review of Fluid Mechanics, Vol. 23, Issue 1 https://doi.org/10.1146/annurev.fl.23.010191.001401	journal	January 1991
Selection of Quantum Dot Wavelengths for Biomedical Assays and Imaging Lim, Yong Taik; Kim, Sungjee; Nakayama, Akira Molecular Imaging, Vol. 2, Issue 1 https://doi.org/10.1162/15353500200302163	journal	January 2003
Ultra-Fast Fluorescence Imaging in Vivo with Conjugated Polymer Fluorophores in the Second Near-Infrared Window Hong, Guosong; Zou, Yingping; Antaris, Alexander L. arXiv https://doi.org/10.48550/arxiv.1406.6452	text	January 2014

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Advances in nanomaterials for brain microscopy Del Bonis-O’Donnell, Jackson T.; Chio, Linda; Dorlhiac, Gabriel F. Nano Research, Vol. 11, Issue 10 https://doi.org/10.1007/s12274-018-2145-2	journal	August 2018
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Orthogonal shortwave infrared emission based on rare earth nanoparticles for interference-free logical codes and bio-imaging Ma, By Liyi; Zhai, Xuejiao; Du, Gaiping Chemical Science, Vol. 10, Issue 11 https://doi.org/10.1039/c8sc05044a	journal	January 2019
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High photoluminescence of shortwave infrared-emitting anisotropic surface charged gold nanoclusters Musnier, Benjamin; Wegner, K. David; Comby-Zerbino, Clothilde Nanoscale, Vol. 11, Issue 25 https://doi.org/10.1039/c9nr04120f	journal	January 2019
A nano-cocktail of an NIR-II emissive fluorophore and organoplatinum( ii ) metallacycle for efficient cancer imaging and therapy Ding, Feng; Chen, Zhao; Kim, Won Young Chemical Science, Vol. 10, Issue 29 https://doi.org/10.1039/c9sc02466b	journal	January 2019
Bright quantum dots emitting at ∼1,600 nm in the NIR-IIb window for deep tissue fluorescence imaging Zhang, Mingxi; Yue, Jingying; Cui, Ran Proceedings of the National Academy of Sciences, Vol. 115, Issue 26 https://doi.org/10.1073/pnas.1806153115	journal	June 2018
Rhomboidal Pt(II) metallacycle-based NIR-II theranostic nanoprobe for tumor diagnosis and image-guided therapy Sun, Yue; Ding, Feng; Zhou, Zhixuan Proceedings of the National Academy of Sciences, Vol. 116, Issue 6 https://doi.org/10.1073/pnas.1817021116	journal	January 2019
Recent advances on fluorescent biomarkers of near-infrared quantum dots for in vitro and in vivo imaging Chinnathambi, Shanmugavel; Shirahata, Naoto Science and Technology of Advanced Materials, Vol. 20, Issue 1 https://doi.org/10.1080/14686996.2019.1590731	journal	April 2019
Upconversion nanoparticles for in vivo applications: limitations and future perspectives del Rosal, Blanca; Jaque, Daniel Methods and Applications in Fluorescence, Vol. 7, Issue 2 https://doi.org/10.1088/2050-6120/ab029f	journal	February 2019
Excitons in InP, GaP, and ${Ga}_{x} {In}_{1 - x} P$ quantum dots: Insights from time-dependent density functional theory Ma, Xiaoyu; Min, Jingjing; Zeng, Zaiping Physical Review B, Vol. 100, Issue 24 https://doi.org/10.1103/physrevb.100.245404	journal	December 2019
Optical fluorescence imaging with shortwave infrared light emitter nanomaterials for in vivo cell tracking in regenerative medicine Fath‐Bayati, Leyla; Vasei, Mohammad; Sharif‐Paghaleh, Ehsan Journal of Cellular and Molecular Medicine, Vol. 23, Issue 12 https://doi.org/10.1111/jcmm.14670	journal	September 2019
Concurrent fluorescence and volumetric optoacoustic tomography of nanoagent perfusion and bio-distribution in solid tumors Chen, Zhenyue; Deán-Ben, Xosé Luis; Liu, Nian Biomedical Optics Express, Vol. 10, Issue 10 https://doi.org/10.1364/boe.10.005093	journal	January 2019
In Vivo Biosensing Using Resonance Energy Transfer Bhuckory, Shashi; Kays, Joshua C.; Dennis, Allison M. Biosensors, Vol. 9, Issue 2 https://doi.org/10.3390/bios9020076	journal	June 2019
Applicability of Supraclavicular Oxygenated and Total Hemoglobin Evaluated by Near-Infrared Time-Resolved Spectroscopy as Indicators of Brown Adipose Tissue Density in Humans Nirengi, Shinsuke; Fuse, Sayuri; Amagasa, Shiho International Journal of Molecular Sciences, Vol. 20, Issue 9 https://doi.org/10.3390/ijms20092214	journal	May 2019
Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis Mangeolle, Tristan; Yakavets, Ilya; Marchal, Sophie Nanomaterials, Vol. 8, Issue 8 https://doi.org/10.3390/nano8080572	journal	July 2018
Biocompatible Semiconductor Quantum Dots as Cancer Imaging Agents McHugh, Kevin J.; Jing, Lihong; Behrens, Adam M. Advanced Materials, Vol. 30, Issue 18 https://doi.org/10.1002/adma.201706356	journal	February 2018
“Dual Lock-and-Key”-Controlled Nanoprobes for Ultrahigh Specific Fluorescence Imaging in the Second Near-Infrared Window Tang, Yufu; Li, Yuanyuan; Hu, Xiaoming Advanced Materials, Vol. 30, Issue 31 https://doi.org/10.1002/adma.201801140	journal	June 2018
Supramolecularly Engineered NIR‐II and Upconversion Nanoparticles In Vivo Assembly and Disassembly to Improve Bioimaging Zhao, Mengyao; Li, Benhao; Wang, Peiyuan Advanced Materials, Vol. 30, Issue 52 https://doi.org/10.1002/adma.201804982	journal	November 2018
Atomic‐Precision Gold Clusters for NIR‐II Imaging Liu, Haile; Hong, Guosong; Luo, Zhentao Advanced Materials, Vol. 31, Issue 46 https://doi.org/10.1002/adma.201901015	journal	September 2019
A General In Situ Growth Strategy of Designing Theranostic NaLnF ₄ @Cu ₂₋ _x S Nanoplatform for In Vivo NIR‐II Optical Imaging Beyond 1500 nm and Photothermal Therapy Jiang, Mingyang; Liu, Hongrong; Zeng, Songjun Advanced Therapeutics, Vol. 2, Issue 6 https://doi.org/10.1002/adtp.201800153	journal	March 2019
Flavylium Polymethine Fluorophores for Near- and Shortwave Infrared Imaging Cosco, Emily D.; Caram, Justin R.; Bruns, Oliver T. Angewandte Chemie International Edition, Vol. 56, Issue 42 https://doi.org/10.1002/anie.201706974	journal	September 2017
An Efficient 1064 nm NIR-II Excitation Fluorescent Molecular Dye for Deep-Tissue High-Resolution Dynamic Bioimaging Li, Benhao; Lu, Lingfei; Zhao, Mengyao Angewandte Chemie International Edition, Vol. 57, Issue 25 https://doi.org/10.1002/anie.201801226	journal	March 2018
Precise In Vivo Inflammation Imaging Using In Situ Responsive Cross-linking of Glutathione-Modified Ultra-Small NIR-II Lanthanide Nanoparticles Zhao, Mengyao; Wang, Rui; Li, Benhao Angewandte Chemie International Edition, Vol. 58, Issue 7 https://doi.org/10.1002/anie.201812878	journal	January 2019
Conjugated‐Polymer‐Based Nanoparticles with Efficient NIR‐II Fluorescent, Photoacoustic and Photothermal Performance Miao, Yawei; Gu, Chuantao; Yu, Bing ChemBioChem, Vol. 20, Issue 21 https://doi.org/10.1002/cbic.201900309	journal	October 2019
Transmission in near-infrared optical windows for deep brain imaging Shi, Lingyan; Sordillo, Laura A.; Rodríguez-Contreras, Adrián Journal of Biophotonics, Vol. 9, Issue 1-2 https://doi.org/10.1002/jbio.201500192	journal	November 2015
Strategies to Overcome Autofluorescence in Nanoprobe-Driven In Vivo Fluorescence Imaging del Rosal, Blanca; Benayas, Antonio Small Methods, Vol. 2, Issue 9 https://doi.org/10.1002/smtd.201800075	journal	June 2018
Lanthanide-doped near-infrared II luminescent nanoprobes for bioapplications Yu, Shaohua; Tu, Datao; Lian, Wei Science China Materials, Vol. 62, Issue 8 https://doi.org/10.1007/s40843-019-9414-4	journal	April 2019
Bioinspired tumor-homing nanosystem for precise cancer therapy via reprogramming of tumor-associated macrophages Huang, Yanyu; Mei, Chaoming; Tian, Yiqiao NPG Asia Materials, Vol. 10, Issue 10 https://doi.org/10.1038/s41427-018-0091-9	journal	October 2018
Intense near-infrared-II luminescence from NaCeF ₄ :Er/Yb nanoprobes for in vitro bioassay and in vivo bioimaging Lei, Xialian; Li, Renfu; Tu, Datao Chemical Science, Vol. 9, Issue 20 https://doi.org/10.1039/c8sc00927a	journal	January 2018
Shortwave infrared fluorescence imaging with the clinically approved near-infrared dye indocyanine green Carr, Jessica A.; Franke, Daniel; Caram, Justin R. Proceedings of the National Academy of Sciences, Vol. 115, Issue 17 https://doi.org/10.1073/pnas.1718917115	journal	April 2018
Absorption by water increases fluorescence image contrast of biological tissue in the shortwave infrared Carr, Jessica A.; Aellen, Marianne; Franke, Daniel Proceedings of the National Academy of Sciences, Vol. 115, Issue 37 https://doi.org/10.1073/pnas.1803210115	journal	August 2018
Performance of optoacoustic and fluorescence imaging in detecting deep-seated fluorescent agents Chen, Zhenyue; Deán-Ben, Xosé Luís; Gottschalk, Sven Biomedical Optics Express, Vol. 9, Issue 5 https://doi.org/10.1364/BOE.9.002229	journal	January 2018
Nano-and Micromotors Designed for Cancer Therapy Sonntag, Luisa; Simmchen, Juliane; Magdanz, Veronika Molecules, Vol. 24, Issue 18 https://doi.org/10.3390/molecules24183410	journal	September 2019
Consensus guidelines for the use and interpretation of angiogenesis assays. Nowak-Sliwinska, Patrycja; Alitalo, Kari; Allen, Elizabeth Springer Netherlands https://doi.org/10.48350/149267	text	January 2018
Concurrent fluorescence and volumetric optoacoustic tomography of nanoagent perfusion and bio-distribution in solid tumors Chen, Zhenyue; Deán-Ben, Xosé Luis; Liu, Nian Optical Society of America https://doi.org/10.5167/uzh-176156	text	January 2019
State-of-the-Art and Trends in Synthesis, Properties, and Application of Quantum Dots-Based Nanomaterials Alizadeh-Ghodsi, Mohammadreza; Pourhassan-Moghaddam, Mohammad; Zavari-Nematabad, Ali Particle & Particle Systems Characterization, Vol. 36, Issue 2 https://doi.org/10.1002/ppsc.201800302	journal	January 2019
Light-sheet microscopy in the near-infrared II window Wang, Feifei; Wan, Hao; Ma, Zhuoran Nature Methods, Vol. 16, Issue 6 https://doi.org/10.1038/s41592-019-0398-7	journal	May 2019
Short-wave infrared emitted/excited fluorescence from carbon dots and preliminary applications in bioimaging Li, Dongyu; Wang, Dan; Zhao, Xinyuan Materials Chemistry Frontiers, Vol. 2, Issue 7 https://doi.org/10.1039/c8qm00151k	journal	January 2018
NIR‐II Excitable Conjugated Polymer Dots with Bright NIR‐I Emission for Deep In Vivo Two‐Photon Brain Imaging Through Intact Skull Wang, Shaowei; Liu, Jie; Feng, Guangxue Advanced Functional Materials, Vol. 29, Issue 15 https://doi.org/10.1002/adfm.201808365	journal	January 2019
High-Capacity Upconversion Wavelength and Lifetime Binary Encoding for Multiplexed Biodetection Zhou, Lei; Fan, Yong; Wang, Rui Angewandte Chemie International Edition, Vol. 57, Issue 39 https://doi.org/10.1002/anie.201808209	journal	August 2018
Optical Multiplexed Bioassays for Improved Biomedical Diagnostics Fan, Yong; Wang, Shangfeng; Zhang, Fan Angewandte Chemie International Edition, Vol. 58, Issue 38 https://doi.org/10.1002/anie.201901964	journal	September 2019
NIR-II fluorescence microscopic imaging of cortical vasculature in non-human primates Cai, Zhaochong; Zhu, Liang; Wang, Mengqi Theranostics, Vol. 10, Issue 9 https://doi.org/10.7150/thno.43533	journal	January 2020
Excitons in InP, GaP, GaInP quantum dots: Insights from time-dependent density functional theory Ma, Xiaoyu; Min, Jingjing; Zeng, Zaiping arXiv https://doi.org/10.48550/arxiv.1908.09430	text	January 2019

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