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Title: Alginate–peptide amphiphile core–shell microparticles as a targeted drug delivery system

Abstract

We describe in this work the synthesis of microparticles with a doxorubicin drug conjugated alginate core and a shell of peptide amphiphile nanofibres functionalized for targeting the folate receptor.

Authors:
 [1];  [2];  [2];  [3];  [3];  [4];  [1]
  1. Simpson Querrey Institute for BioNanotechnology; Chicago; USA; Department of Chemistry; Department of Biomedical Engineering
  2. Simpson Querrey Institute for BioNanotechnology; Chicago; USA; Department of Materials Science and Engineering; Northwestern University
  3. Department of Chemistry; Department of Biomedical Engineering; Department of Chemical Engineering; Northwestern University; Evanston
  4. Simpson Querrey Institute for BioNanotechnology; Chicago; USA
Publication Date:
Research Org.:
Energy Frontier Research Centers (EFRC) (United States). Center for Bio-Inspired Energy Science (CBES)
Sponsoring Org.:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22)
OSTI Identifier:
1385391
DOE Contract Number:
SC0000989
Resource Type:
Journal Article
Resource Relation:
Journal Name: RSC Advances; Journal Volume: 5; Journal Issue: 12; Related Information: CBES partners with Northwestern University (lead); Harvard University; New York University; Pennsylvania State University; University of Michigan; University of Pittsburgh
Country of Publication:
United States
Language:
English
Subject:
catalysis (homogeneous), solar (photovoltaic), bio-inspired, charge transport, mesostructured materials, materials and chemistry by design, synthesis (novel materials), synthesis (self-assembly)

Citation Formats

Boekhoven, Job, Zha, R. Helen, Tantakitti, Faifan, Zhuang, Ellen, Zandi, Roya, Newcomb, Christina J., and Stupp, Samuel I.. Alginate–peptide amphiphile core–shell microparticles as a targeted drug delivery system. United States: N. p., 2015. Web. doi:10.1039/c4ra16593d.
Boekhoven, Job, Zha, R. Helen, Tantakitti, Faifan, Zhuang, Ellen, Zandi, Roya, Newcomb, Christina J., & Stupp, Samuel I.. Alginate–peptide amphiphile core–shell microparticles as a targeted drug delivery system. United States. doi:10.1039/c4ra16593d.
Boekhoven, Job, Zha, R. Helen, Tantakitti, Faifan, Zhuang, Ellen, Zandi, Roya, Newcomb, Christina J., and Stupp, Samuel I.. Thu . "Alginate–peptide amphiphile core–shell microparticles as a targeted drug delivery system". United States. doi:10.1039/c4ra16593d.
@article{osti_1385391,
title = {Alginate–peptide amphiphile core–shell microparticles as a targeted drug delivery system},
author = {Boekhoven, Job and Zha, R. Helen and Tantakitti, Faifan and Zhuang, Ellen and Zandi, Roya and Newcomb, Christina J. and Stupp, Samuel I.},
abstractNote = {We describe in this work the synthesis of microparticles with a doxorubicin drug conjugated alginate core and a shell of peptide amphiphile nanofibres functionalized for targeting the folate receptor.},
doi = {10.1039/c4ra16593d},
journal = {RSC Advances},
number = 12,
volume = 5,
place = {United States},
year = {Thu Jan 01 00:00:00 EST 2015},
month = {Thu Jan 01 00:00:00 EST 2015}
}