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Title: Effect of charge, hydrophobicity, and sequence of nucleoporins on the translocation of model particles through the nuclear pore complex

Authors:
; ; ; ;
Publication Date:
Research Org.:
Energy Frontier Research Centers (EFRC) (United States). Center for Bio-Inspired Energy Science (CBES)
Sponsoring Org.:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22)
OSTI Identifier:
1384626
DOE Contract Number:  
SC0000989
Resource Type:
Journal Article
Journal Name:
Proceedings of the National Academy of Sciences of the United States of America
Additional Journal Information:
Journal Volume: 110; Journal Issue: 9; Related Information: CBES partners with Northwestern University (lead); Harvard University; New York University; Pennsylvania State University; University of Michigan; University of Pittsburgh; Journal ID: ISSN 0027-8424
Publisher:
National Academy of Sciences, Washington, DC (United States)
Country of Publication:
United States
Language:
English
Subject:
catalysis (homogeneous), solar (photovoltaic), bio-inspired, charge transport, mesostructured materials, materials and chemistry by design, synthesis (novel materials), synthesis (self-assembly)

Citation Formats

Tagliazucchi, Mario, Peleg, Orit, Kröger, Martin, Rabin, Yitzhak, and Szleifer, Igal. Effect of charge, hydrophobicity, and sequence of nucleoporins on the translocation of model particles through the nuclear pore complex. United States: N. p., 2013. Web. doi:10.1073/pnas.1212909110.
Tagliazucchi, Mario, Peleg, Orit, Kröger, Martin, Rabin, Yitzhak, & Szleifer, Igal. Effect of charge, hydrophobicity, and sequence of nucleoporins on the translocation of model particles through the nuclear pore complex. United States. doi:10.1073/pnas.1212909110.
Tagliazucchi, Mario, Peleg, Orit, Kröger, Martin, Rabin, Yitzhak, and Szleifer, Igal. Tue . "Effect of charge, hydrophobicity, and sequence of nucleoporins on the translocation of model particles through the nuclear pore complex". United States. doi:10.1073/pnas.1212909110.
@article{osti_1384626,
title = {Effect of charge, hydrophobicity, and sequence of nucleoporins on the translocation of model particles through the nuclear pore complex},
author = {Tagliazucchi, Mario and Peleg, Orit and Kröger, Martin and Rabin, Yitzhak and Szleifer, Igal},
abstractNote = {},
doi = {10.1073/pnas.1212909110},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
issn = {0027-8424},
number = 9,
volume = 110,
place = {United States},
year = {2013},
month = {2}
}

Works referenced in this record:

The Structure of the Nuclear Pore Complex
journal, July 2011


The Yeast Nuclear Pore Complex: Composition, Architecture, and Transport Mechanism
journal, February 2000

  • Rout, Michael P.; Aitchison, John D.; Suprapto, Adisetyantari
  • The Journal of Cell Biology, Vol. 148, Issue 4
  • DOI: 10.1083/jcb.148.4.635

Transport-Related Structures and Processes of the Nuclear Pore Complex Studied through Molecular Dynamics
journal, March 2009


Simulations of nuclear pore transport yield mechanistic insights and quantitative predictions
journal, June 2011

  • Mincer, J. S.; Simon, S. M.
  • Proceedings of the National Academy of Sciences, Vol. 108, Issue 31
  • DOI: 10.1073/pnas.1104521108

Amyloid-like interactions within nucleoporin FG hydrogels
journal, March 2010

  • Ader, C.; Frey, S.; Maas, W.
  • Proceedings of the National Academy of Sciences, Vol. 107, Issue 14
  • DOI: 10.1073/pnas.0910163107

Probing a Structural Model of the Nuclear Pore Complex Channel through Molecular Dynamics
journal, April 2010


Interaction between NTF2 and xFxFG-containing nucleoporins is required to mediate nuclear import of RanGDP 1 1Edited by I. B. Holland
journal, October 1999

  • Bayliss, Richard; Ribbeck, Katharina; Akin, Debra
  • Journal of Molecular Biology, Vol. 293, Issue 3
  • DOI: 10.1006/jmbi.1999.3166

Nucleocytoplasmic Transport: Navigating the Channel: Nucleocytoplasmic Transport
journal, March 2003


Self-organization of grafted polyelectrolyte layers via the coupling of chemical equilibrium and physical interactions
journal, March 2010

  • Tagliazucchi, M.; de la Cruz, M. O.; Szleifer, I.
  • Proceedings of the National Academy of Sciences, Vol. 107, Issue 12
  • DOI: 10.1073/pnas.0913340107

Natively Unfolded Nucleoporins Gate Protein Diffusion across the Nuclear Pore Complex
journal, April 2007


Determining the architectures of macromolecular assemblies
journal, November 2007

  • Alber, Frank; Dokudovskaya, Svetlana; Veenhoff, Liesbeth M.
  • Nature, Vol. 450, Issue 7170
  • DOI: 10.1038/nature06404

Ion Transport and Molecular Organization Are Coupled in Polyelectrolyte-Modified Nanopores
journal, November 2011

  • Tagliazucchi, Mario; Rabin, Yitzhak; Szleifer, Igal
  • Journal of the American Chemical Society, Vol. 133, Issue 44
  • DOI: 10.1021/ja2063605

The molecular architecture of the nuclear pore complex
journal, November 2007

  • Alber, Frank; Dokudovskaya, Svetlana; Veenhoff, Liesbeth M.
  • Nature, Vol. 450, Issue 7170
  • DOI: 10.1038/nature06405

Weak polyelectrolytes tethered to surfaces: Effect of geometry, acid–base equilibrium and electrical permittivity
journal, January 2006

  • Nap, Rikkert; Gong, Peng; Szleifer, Igal
  • Journal of Polymer Science Part B: Polymer Physics, Vol. 44, Issue 18
  • DOI: 10.1002/polb.20896

Brownian Dynamics Simulation of Nucleocytoplasmic Transport: A Coarse-Grained Model for the Functional State of the Nuclear Pore Complex
journal, June 2011


How and Why Nanoparticle’s Curvature Regulates the Apparent p K a of the Coating Ligands
journal, February 2011

  • Wang, Dawei; Nap, Rikkert J.; Lagzi, István
  • Journal of the American Chemical Society, Vol. 133, Issue 7
  • DOI: 10.1021/ja108154a

Nanomechanical Basis of Selective Gating by the Nuclear Pore Complex
journal, October 2007

  • Lim, Roderick Y. H.; Fahrenkrog, Birthe; Köser, Joachim
  • Science, Vol. 318, Issue 5850
  • DOI: 10.1126/science.1145980

Kinetic analysis of translocation through nuclear pore complexes
journal, March 2001


The Part and the Whole: functions of nucleoporins in nucleocytoplasmic transport
journal, August 2010


Morphology Control of Hairy Nanopores
journal, May 2011

  • Peleg, Orit; Tagliazucchi, Mario; Kröger, Martin
  • ACS Nano, Vol. 5, Issue 6
  • DOI: 10.1021/nn200702u

Imaging of single-molecule translocation through nuclear pore complexes
journal, August 2004

  • Yang, W.; Gelles, J.; Musser, S. M.
  • Proceedings of the National Academy of Sciences, Vol. 101, Issue 35
  • DOI: 10.1073/pnas.0403675101

Efficiency, Selectivity, and Robustness of Nucleocytoplasmic Transport
journal, January 2007


Virtual gating and nuclear transport: the hole picture
journal, December 2003