Nondisruptive Dissolution of Hyperpolarized 129Xe into Viscous Aqueous and Organic Liquid Crystalline Environments

Truxal, Ashley E.; Slack, Clancy C.; Gomes, Muller D.; Vassiliou, Christophoros C.; Wemmer, David E.; Pines, Alexander

doi:10.1002/anie.201511539

Title: Nondisruptive Dissolution of Hyperpolarized ¹²⁹Xe into Viscous Aqueous and Organic Liquid Crystalline Environments

Journal Article · Tue Mar 08 00:00:00 EST 2016 · Angewandte Chemie (International Edition)

DOI:https://doi.org/10.1002/anie.201511539· OSTI ID:1379274

Truxal, Ashley E. ^[1]; Slack, Clancy C. ^[1]; Gomes, Muller D. ^[1]; Vassiliou, Christophoros C. ^[1]; Wemmer, David E. ^[2]; Pines, Alexander ^[1]

University of California, Berkeley, CA (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States). Materials Sciences Division
University of California, Berkeley, CA (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Studies of hyperpolarized xenon-129 (hp-¹²⁹Xe) in media such as liquid crystals and cell suspensions are in demand for applications ranging from biomedical imaging to materials engineering but have been hindered by the inability to bubble Xe through the desired media as a result of viscosity or perturbations caused by bubbles. In this paper a device is reported that can be reliably used to dissolve hp-¹²⁹Xe into viscous aqueous and organic samples without bubbling. This method is robust, requires small sample volumes (<60 μL), is compatible with existing NMR hardware, and is made from readily available materials. Experiments show that Xe can be introduced into viscous and aligned media without disrupting molecular order. We detected dissolved xenon in an aqueous liquid crystal that is disrupted by the shear forces of bubbling, and we observed liquid-crystal phase transitions in (MBBA). This tool allows an entirely new class of samples to be investigated by hyperpolarized-gas NMR spectroscopy.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES). Materials Sciences & Engineering Division (MSE); National Science Foundation (NSF)

Grant/Contract Number:: AC02-05CH11231; DGE-1106400

OSTI ID:: 1379274

Journal Information:: Angewandte Chemie (International Edition), Vol. 55, Issue 15; ISSN 1433-7851

Publisher:: WileyCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 8 works

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