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Title: A Compact Energy-Independent CZT-Based Gamma Camera

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Publication Date:
Research Org.:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Org.:
National Institute of Health
OSTI Identifier:
Report Number(s):
R&D Project: 87106
DOE Contract Number:
Resource Type:
Resource Relation:
Conference: SPIE Optical Engineering + Applications 2017; San Diego; 20170806 through 20170810
Country of Publication:
United States
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; CZT; gamma camera; energy discrimination; ASIC; compact camera

Citation Formats

Seo Y., OConnor, P., Huang, Q., James, R. B., Mitra, D., and Pan, H. A Compact Energy-Independent CZT-Based Gamma Camera. United States: N. p., 2017. Web.
Seo Y., OConnor, P., Huang, Q., James, R. B., Mitra, D., & Pan, H. A Compact Energy-Independent CZT-Based Gamma Camera. United States.
Seo Y., OConnor, P., Huang, Q., James, R. B., Mitra, D., and Pan, H. 2017. "A Compact Energy-Independent CZT-Based Gamma Camera". United States. doi:.
title = {A Compact Energy-Independent CZT-Based Gamma Camera},
author = {Seo Y. and OConnor, P. and Huang, Q. and James, R. B. and Mitra, D. and Pan, H.},
abstractNote = {},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = 2017,
month = 8

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  • In this paper, we discuss the design of a compact gamma camera for high-resolution prostate cancer imaging using Cadmium Zinc Telluride (CdZnTe or CZT) radiation detectors. Prostate cancer is a common disease in men. Nowadays, a blood test measuring the level of prostate specific antigen (PSA) is widely used for screening for the disease in males over 50, followed by (ultrasound) imaging-guided biopsy. However, PSA tests have a high false-positive rate and ultrasound-guided biopsy has a high likelihood of missing small cancerous tissues. Commercial methods of nuclear medical imaging, e.g. PET and SPECT, can functionally image the organs, and potentiallymore » find cancer tissues at early stages, but their applications in diagnosing prostate cancer has been limited by the smallness of the prostate gland and the long working distance between the organ and the detectors comprising these imaging systems. CZT is a semiconductor material with wide band-gap and relatively high electron mobility, and thus can operate at room temperature without additional cooling. CZT detectors are photon-electron direct-conversion devices, thus offering high energy-resolution in detecting gamma rays, enabling energy-resolved imaging, and reducing the background of Compton-scattering events. In addition, CZT material has high stopping power for gamma rays; for medical imaging, a few-mm-thick CZT material provides adequate detection efficiency for many SPECT radiotracers. Because of these advantages, CZT detectors are becoming popular for several SPECT medical-imaging applications. Most recently, we designed a compact gamma camera using CZT detectors coupled to an application-specific-integrated-circuit (ASIC). This camera functions as a trans-rectal probe to image the prostate gland from a distance of only 1-5 cm, thus offering higher detection efficiency and higher spatial resolution. Hence, it potentially can detect prostate cancers at their early stages. The performance tests of this camera have been completed. The results show better than 6-mm resolution at a distance of 1 cm. Details of the test results are discussed in this paper.« less
  • A dual-energy tandem-type gamma generator has been developed at E.O. Lawrence Berkeley National Laboratory and Sandia National Laboratories. The tandem accelerator geometry allows higher energy nuclear reactions to be reached, thereby allowing more flexible generation of MeV-energy gammas for active interrogation applications.