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Title: Insights into links between autophagy and the ubiquitin system from the structure of LC3B bound to the LIR motif from the E3 ligase NEDD4: Crystal Structure of LC3B Bound to LIR from NEDD4

Journal Article · · Protein Science
DOI:https://doi.org/10.1002/pro.3186· OSTI ID:1374615
 [1];  [2];  [1];  [3]
  1. Department of Structural Biology, St. Jude Children's Research Hospital, Memphis Tennessee 38105
  2. Department of Structural Biology, St. Jude Children's Research Hospital, Memphis Tennessee 38105; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis Tennessee 38103
  3. Department of Structural Biology, St. Jude Children's Research Hospital, Memphis Tennessee 38105; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis Tennessee 38103; Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis Tennessee 38105

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
DOE - BASIC ENERGY SCIENCESNIHHHMI
OSTI ID:
1374615
Journal Information:
Protein Science, Vol. 26, Issue 8; ISSN 0961-8368
Publisher:
The Protein Society
Country of Publication:
United States
Language:
ENGLISH

References (24)

Structural Basis of the Autophagy-Related LC3/Atg13 LIR Complex: Recognition and Interaction Mechanism journal January 2014
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing journal November 2000
Historical landmarks of autophagy research journal December 2013
Cargo recognition and trafficking in selective autophagy journal May 2014
Autophagy: Renovation of Cells and Tissues journal November 2011
Versatile Roles of K63-Linked Ubiquitin Chains in Trafficking journal November 2014
A ubiquitin-like system mediates protein lipidation journal November 2000
Dali server: conservation mapping in 3D journal May 2010
The ATG conjugation systems are important for degradation of the inner autophagosomal membrane journal October 2016
Autophagic Clearance of PolyQ Proteins Mediated by Ubiquitin-Atg8 Adaptors of the Conserved CUET Protein Family journal July 2014
Quantifying Ubiquitin Signaling journal May 2015
Structural Basis for Sorting Mechanism of p62 in Selective Autophagy journal August 2008
Eaten alive: a history of macroautophagy journal September 2010
The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications journal May 2015
System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes journal April 2016
Structural basis of target recognition by Atg8/LC3 during selective autophagy journal October 2008
Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis journal November 2014
Ubiquitin-Dependent And Independent Signals In Selective Autophagy journal January 2016
PINK1- and Parkin-mediated mitophagy at a glance journal February 2012
Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy journal January 2014
Phaser crystallographic software journal July 2007
Autophagy in Human Health and Disease journal February 2013
Network organization of the human autophagy system journal June 2010
The autophagosome: origins unknown, biogenesis complex journal November 2013

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