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Title: Thionin-D4E1 chimeric protein protects plants against bacterial infections

Abstract

The generation of a chimeric protein containing a first domain encoding either a pro-thionon or thionin, a second domain encoding D4E1 or pro-D4E1, and a third domain encoding a peptide linker located between the first domain and second domain is described. Either the first domain or the second domain is located at the amino terminal of the chimeric protein and the other domain (second domain or first domain, respectively) is located at the carboxyl terminal. The chimeric protein has antibacterial activity. Genetically altered plants and their progeny expressing a polynucleotide encoding the chimeric protein resist diseases caused by bacteria.

Inventors:
; ;
Publication Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1374580
Patent Number(s):
9,725,734
Application Number:
14/691,780
Assignee:
The United States of America, as represented by the Secretary of Agriculture
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Resource Relation:
Patent File Date: 2015 Apr 21
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Stover, Eddie W, Gupta, Goutam, and Hao, Guixia. Thionin-D4E1 chimeric protein protects plants against bacterial infections. United States: N. p., 2017. Web.
Stover, Eddie W, Gupta, Goutam, & Hao, Guixia. Thionin-D4E1 chimeric protein protects plants against bacterial infections. United States.
Stover, Eddie W, Gupta, Goutam, and Hao, Guixia. 2017. "Thionin-D4E1 chimeric protein protects plants against bacterial infections". United States. https://www.osti.gov/servlets/purl/1374580.
@article{osti_1374580,
title = {Thionin-D4E1 chimeric protein protects plants against bacterial infections},
author = {Stover, Eddie W and Gupta, Goutam and Hao, Guixia},
abstractNote = {The generation of a chimeric protein containing a first domain encoding either a pro-thionon or thionin, a second domain encoding D4E1 or pro-D4E1, and a third domain encoding a peptide linker located between the first domain and second domain is described. Either the first domain or the second domain is located at the amino terminal of the chimeric protein and the other domain (second domain or first domain, respectively) is located at the carboxyl terminal. The chimeric protein has antibacterial activity. Genetically altered plants and their progeny expressing a polynucleotide encoding the chimeric protein resist diseases caused by bacteria.},
doi = {},
url = {https://www.osti.gov/biblio/1374580}, journal = {},
number = ,
volume = ,
place = {United States},
year = {2017},
month = {8}
}

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