skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Electrochemical detection of single molecules using abiotic nanopores having electrically tunable dimensions

Patent ·
OSTI ID:1371700
; ; ; ;

A barrier structure for use in an electrochemical stochastic membrane sensor for single molecule detection. The sensor is based upon inorganic nanopores having electrically tunable dimensions. The inorganic nanopores are formed from inorganic materials and an electrically conductive polymer. Methods of making the barrier structure and sensing single molecules using the barrier structure are also described.

Research Organization:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC 52-06 NA 25396
Assignee:
LOS ALAMOS NATIONAL SECURITY, LLC
Patent Number(s):
RE46,479
Application Number:
13/339,010
OSTI ID:
1371700
Resource Relation:
Patent File Date: 2011 Dec 28
Country of Publication:
United States
Language:
English

References (45)

Process of depositing by electropolymerization a film of a composite material onto an electrically conductive surface patent November 1996
Valves activated by electrically active polymers or by shape-memory materials, device containing same and method for using same patent February 2006
Embedded control valve using electroactive material patent January 2007
Methods and apparatus for characterizing polynucleotides patent July 2007
Nanopore with resonant tunneling electrodes patent July 2007
Methods of fabrication employing nanoscale mandrels patent June 2009
Capillary electrophoresis method patent December 2009
Electrochemical detection of single molecules using abiotic nanopores having electrically tunable dimensions patent December 2009
Method and apparatus for combined electrochemical synthesis and detection of analytes patent April 2011
Apparatus and method for molecular separation, purification, and sensing patent March 2015
Method and apparatus for analysis of biological solutions patent-application October 2002
Small molecule microarrays patent-application February 2003
Nanostructured material transport devices and their fabrication by application of molecular coatings to nanoscale channels patent-application February 2005
Molecular resonant tunneling sensor and methods of fabricating and using the same patent-application October 2006
Method and apparatus to fabricate polymer arrays on patterned wafers using electrochemical synthesis patent-application December 2006
Electropolymerization method for preparing nano-tube type conducting polymer using porous template, method for preparing electrochromic device, and electrochromic device prepared therefrom patent-application May 2007
Nanopore sensor system patent-application December 2007
Method and apparatus for combined electrochemical synthesis and detection of analytes patent-application July 2008
Microarray Device patent-application December 2008
Formation of Layers of Amphiphilic Molecules patent-application July 2009
Electrochemical Detection Of Single Molecules Using Abiotic Nanopores Having Electrically Tunable Dimensions patent-application November 2009
Nanopore Based Ion-Selective Electrodes patent-application February 2010
Immobilized Nucleic Acid Complexes For Sequence Analysis patent-application March 2010
Electrical Double Layer Capacitive Devices And Methods Of Using Same For Sequencing Polymers And Detecting Analytes patent-application November 2010
Devices And Methods For Analyzing Biomolecules And Probes Bound Thereto patent-application December 2010
Nanofludic Field Effect Transistor Based On Surface Charge Modulated Nanochannel patent-application December 2010
Nanopore Sequencing Devices And Methods patent-application December 2010
Conductivity sensor device comprising diamond film with at least one nanopore or micorpore patent-application May 2011
Geometric Patterns And Lipid Bilayers For Dna Molecule Organization And Uses Thereof patent-application June 2011
Method Of Fabrication Of Monolithic Stationary Phases For Separations, And Methods Of Separation Using Such Stationary Phases patent-application December 2011
Multiple Walled Nested Coaxial Nanostructures patent-application February 2012
Nanopore-Based Nanoparticle Translocation Devices patent-application April 2012
Controlling Translocation Through Nanopores With Fluid Wall patent-application February 2013
Stochastic sensors journal January 2005
Continuous base identification for single-molecule nanopore DNA sequencing journal February 2009
Electrooxidative Deposition of Polypyrrole and Polyaniline on Self-Assembled Monolayer Modified Electrodes journal February 1997
Nanopore DNA sequencing with MspA journal August 2010
Conducting polymer polypyrrole supported bilayer lipid membranes journal January 2005
Reversible Conversion of Conducting Polymer Films from Superhydrophobic to Superhydrophilic journal September 2005
Synthesis of heterosegment-junctioned hybrid nanotubes of polythiophene and heterometallic nanoparticles by sequential template-based electropolymerization journal January 2011
Resistive-Pulse Sensing - From Microbes to Molecules journal July 2000
Miniaturized biochemical sensing devices based on planar bilayer lipid membranes journal September 2001
Single Ion Channel Sensitivity in Suspended Bilayers on Micromachined Supports journal February 2001
An Asymmetric Polymer Nanopore for Single Molecule Detection journal March 2004
An Artificial Nanopore for Molecular Sensing journal January 2003

Similar Records

Related Subjects

47 OTHER INSTRUMENTATION