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Title: Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia

Abstract

Postmortem brain studies support dysregulated expression of the histone deacetylase enzymes, HDAC1 and HDAC2, as a central feature in diseases including schizophrenia, bipolar disorder, and depression.

Authors:
ORCiD logo; ; ; ; ; ; ;
Publication Date:
Research Org.:
Brigham and Women's Hospital (Harvard Medical School), Boston, MA (United States). Massachusetts General Hospital
Sponsoring Org.:
USDOE
OSTI Identifier:
1357307
Alternate Identifier(s):
OSTI ID: 1426181
Grant/Contract Number:  
SC0008430
Resource Type:
Journal Article: Published Article
Journal Name:
ACS Chemical Neuroscience
Additional Journal Information:
Journal Name: ACS Chemical Neuroscience Journal Volume: 8 Journal Issue: 3; Journal ID: ISSN 1948-7193
Publisher:
American Chemical Society
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Schroeder, Frederick A., Gilbert, Tonya M., Feng, Ningping, Taillon, Brendan D., Volkow, Nora D., Innis, Robert B., Hooker, Jacob M., and Lipska, Barbara K. Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia. United States: N. p., 2016. Web. doi:10.1021/acschemneuro.6b00372.
Schroeder, Frederick A., Gilbert, Tonya M., Feng, Ningping, Taillon, Brendan D., Volkow, Nora D., Innis, Robert B., Hooker, Jacob M., & Lipska, Barbara K. Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia. United States. https://doi.org/10.1021/acschemneuro.6b00372
Schroeder, Frederick A., Gilbert, Tonya M., Feng, Ningping, Taillon, Brendan D., Volkow, Nora D., Innis, Robert B., Hooker, Jacob M., and Lipska, Barbara K. 2016. "Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia". United States. https://doi.org/10.1021/acschemneuro.6b00372.
@article{osti_1357307,
title = {Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia},
author = {Schroeder, Frederick A. and Gilbert, Tonya M. and Feng, Ningping and Taillon, Brendan D. and Volkow, Nora D. and Innis, Robert B. and Hooker, Jacob M. and Lipska, Barbara K.},
abstractNote = {Postmortem brain studies support dysregulated expression of the histone deacetylase enzymes, HDAC1 and HDAC2, as a central feature in diseases including schizophrenia, bipolar disorder, and depression.},
doi = {10.1021/acschemneuro.6b00372},
url = {https://www.osti.gov/biblio/1357307}, journal = {ACS Chemical Neuroscience},
issn = {1948-7193},
number = 3,
volume = 8,
place = {United States},
year = {Tue Dec 13 00:00:00 EST 2016},
month = {Tue Dec 13 00:00:00 EST 2016}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record at https://doi.org/10.1021/acschemneuro.6b00372

Citation Metrics:
Cited by: 31 works
Citation information provided by
Web of Science

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Works referenced in this record:

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