Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia
Abstract
Postmortem brain studies support dysregulated expression of the histone deacetylase enzymes, HDAC1 and HDAC2, as a central feature in diseases including schizophrenia, bipolar disorder, and depression.
- Authors:
- Publication Date:
- Research Org.:
- Brigham and Women's Hospital (Harvard Medical School), Boston, MA (United States). Massachusetts General Hospital
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1357307
- Alternate Identifier(s):
- OSTI ID: 1426181
- Grant/Contract Number:
- SC0008430
- Resource Type:
- Journal Article: Published Article
- Journal Name:
- ACS Chemical Neuroscience
- Additional Journal Information:
- Journal Name: ACS Chemical Neuroscience Journal Volume: 8 Journal Issue: 3; Journal ID: ISSN 1948-7193
- Publisher:
- American Chemical Society
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Schroeder, Frederick A., Gilbert, Tonya M., Feng, Ningping, Taillon, Brendan D., Volkow, Nora D., Innis, Robert B., Hooker, Jacob M., and Lipska, Barbara K. Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia. United States: N. p., 2016.
Web. doi:10.1021/acschemneuro.6b00372.
Schroeder, Frederick A., Gilbert, Tonya M., Feng, Ningping, Taillon, Brendan D., Volkow, Nora D., Innis, Robert B., Hooker, Jacob M., & Lipska, Barbara K. Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia. United States. https://doi.org/10.1021/acschemneuro.6b00372
Schroeder, Frederick A., Gilbert, Tonya M., Feng, Ningping, Taillon, Brendan D., Volkow, Nora D., Innis, Robert B., Hooker, Jacob M., and Lipska, Barbara K. 2016.
"Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia". United States. https://doi.org/10.1021/acschemneuro.6b00372.
@article{osti_1357307,
title = {Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia},
author = {Schroeder, Frederick A. and Gilbert, Tonya M. and Feng, Ningping and Taillon, Brendan D. and Volkow, Nora D. and Innis, Robert B. and Hooker, Jacob M. and Lipska, Barbara K.},
abstractNote = {Postmortem brain studies support dysregulated expression of the histone deacetylase enzymes, HDAC1 and HDAC2, as a central feature in diseases including schizophrenia, bipolar disorder, and depression.},
doi = {10.1021/acschemneuro.6b00372},
url = {https://www.osti.gov/biblio/1357307},
journal = {ACS Chemical Neuroscience},
issn = {1948-7193},
number = 3,
volume = 8,
place = {United States},
year = {Tue Dec 13 00:00:00 EST 2016},
month = {Tue Dec 13 00:00:00 EST 2016}
}
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Cited by: 31 works
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