Covalent Guanosine Mimetic Inhibitors of G12C KRAS
Journal Article
·
· ACS Medicinal Chemistry Letters
- Research Organization:
- Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
- Sponsoring Organization:
- INDUSTRYOTHER
- OSTI ID:
- 1347801
- Journal Information:
- ACS Medicinal Chemistry Letters, Vol. 8, Issue 1; ISSN 1948-5875
- Publisher:
- American Chemical Society (ACS)
- Country of Publication:
- United States
- Language:
- ENGLISH
Similar Records
The reactivity-driven biochemical mechanism of covalent KRASG12C inhibitors
Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRAS G12C
Discovery of a Covalent Inhibitor of KRAS[superscript G12C] (AMG 510) for the Treatment of Solid Tumors
Journal Article
·
Mon May 14 00:00:00 EDT 2018
· Nature Structural & Molecular Biology
·
OSTI ID:1347801
+7 more
Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRAS G12C
Journal Article
·
Tue Aug 06 00:00:00 EDT 2019
· ACS Medicinal Chemistry Letters
·
OSTI ID:1347801
+24 more
Discovery of a Covalent Inhibitor of KRAS[superscript G12C] (AMG 510) for the Treatment of Solid Tumors
Journal Article
·
Wed Jan 22 00:00:00 EST 2020
· J. Med. Chem.
·
OSTI ID:1347801
+42 more