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Title: Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors: ZMPSTE24 Structure and Inhibition

Authors:
 [1];  [2];  [1];  [3]
  1. Department of Pediatrics, University of Rochester Medical Center, Rochester New York 14642
  2. Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester New York 14642
  3. Department of Pediatrics, University of Rochester Medical Center, Rochester New York 14642; Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester New York 14642
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
National Institutes of Health (NIH)
OSTI Identifier:
1347782
Resource Type:
Journal Article
Journal Name:
Protein Science
Additional Journal Information:
Journal Volume: 26; Journal Issue: 2; Journal ID: ISSN 0961-8368
Publisher:
The Protein Society
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Clark, Kathleen M., Jenkins, Jermaine L., Fedoriw, Nadia, and Dumont, Mark E. Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors: ZMPSTE24 Structure and Inhibition. United States: N. p., 2016. Web. doi:10.1002/pro.3074.
Clark, Kathleen M., Jenkins, Jermaine L., Fedoriw, Nadia, & Dumont, Mark E. Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors: ZMPSTE24 Structure and Inhibition. United States. https://doi.org/10.1002/pro.3074
Clark, Kathleen M., Jenkins, Jermaine L., Fedoriw, Nadia, and Dumont, Mark E. Fri . "Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors: ZMPSTE24 Structure and Inhibition". United States. https://doi.org/10.1002/pro.3074.
@article{osti_1347782,
title = {Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors: ZMPSTE24 Structure and Inhibition},
author = {Clark, Kathleen M. and Jenkins, Jermaine L. and Fedoriw, Nadia and Dumont, Mark E.},
abstractNote = {},
doi = {10.1002/pro.3074},
url = {https://www.osti.gov/biblio/1347782}, journal = {Protein Science},
issn = {0961-8368},
number = 2,
volume = 26,
place = {United States},
year = {2016},
month = {11}
}

Works referenced in this record:

A Facile Method for High-throughput Co-expression of Protein Pairs
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Lamin A-Dependent Nuclear Defects in Human Aging
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HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells
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Structural basis of the action of thermolysin and related zinc peptidases
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The Protease Ste24 Clears Clogged Translocons
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Structural analysis of zinc substitutions in the active site of thermolysin
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Purification of transmembrane proteins from Saccharomyces cerevisiae for X-ray crystallography
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The MORPHEUS protein crystallization screen
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Human ZMPSTE24 disease mutations: residual proteolytic activity correlates with disease severity
journal, June 2012


Structure of the Integral Membrane Protein CAAX Protease Ste24p
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Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome
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The Structural Basis of ZMPSTE24-Dependent Laminopathies
journal, March 2013


The PDB_REDO server for macromolecular structure model optimization
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