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Title: Positron emission tomography probe to monitor selected sugar metabolism in vivo

Abstract

The invention disclosed herein discloses selected ribose isomers that are useful as PET probes (e.g. [18F]-2-fluoro-2-deoxy-arabinose). These PET probes are useful, for example, in methods designed to monitor physiological processes including ribose metabolism and/or to selectively observe certain tissue/organs in vivo. The invention disclosed herein further provides methods for making and using such probes.

Inventors:
; ; ; ;
Publication Date:
Research Org.:
The Regents of the University of California, Oakland, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1346982
Patent Number(s):
9,592,309
Application Number:
14/399,701
Assignee:
The Regents of the University of California CHO
DOE Contract Number:  
SC0001249
Resource Type:
Patent
Resource Relation:
Patent File Date: 2013 May 09
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; 47 OTHER INSTRUMENTATION

Citation Formats

Witte, Owen, Clark, Peter M., Castillo, Blanca Graciela Flores, Jung, Michael E., and Evdokimov, Nikolai M.. Positron emission tomography probe to monitor selected sugar metabolism in vivo. United States: N. p., 2017. Web.
Witte, Owen, Clark, Peter M., Castillo, Blanca Graciela Flores, Jung, Michael E., & Evdokimov, Nikolai M.. Positron emission tomography probe to monitor selected sugar metabolism in vivo. United States.
Witte, Owen, Clark, Peter M., Castillo, Blanca Graciela Flores, Jung, Michael E., and Evdokimov, Nikolai M.. Tue . "Positron emission tomography probe to monitor selected sugar metabolism in vivo". United States. doi:. https://www.osti.gov/servlets/purl/1346982.
@article{osti_1346982,
title = {Positron emission tomography probe to monitor selected sugar metabolism in vivo},
author = {Witte, Owen and Clark, Peter M. and Castillo, Blanca Graciela Flores and Jung, Michael E. and Evdokimov, Nikolai M.},
abstractNote = {The invention disclosed herein discloses selected ribose isomers that are useful as PET probes (e.g. [18F]-2-fluoro-2-deoxy-arabinose). These PET probes are useful, for example, in methods designed to monitor physiological processes including ribose metabolism and/or to selectively observe certain tissue/organs in vivo. The invention disclosed herein further provides methods for making and using such probes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 14 00:00:00 EDT 2017},
month = {Tue Mar 14 00:00:00 EDT 2017}
}

Patent:

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