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Title: Fluid delivery manifolds and microfluidic systems

Abstract

Embodiments of fluid distribution manifolds, cartridges, and microfluidic systems are described herein. Fluid distribution manifolds may include an insert member and a manifold base and may define a substantially closed channel within the manifold when the insert member is press-fit into the base. Cartridges described herein may allow for simultaneous electrical and fluidic interconnection with an electrical multiplex board and may be held in place using magnetic attraction.

Inventors:
; ; ; ; ; ;
Publication Date:
Research Org.:
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1345393
Patent Number(s):
9,579,649
Application Number:
12/900,276
Assignee:
Sandia Corporation SNL-A
DOE Contract Number:
AC04-94AL85000
Resource Type:
Patent
Resource Relation:
Patent File Date: 2010 Oct 07
Country of Publication:
United States
Language:
English
Subject:
42 ENGINEERING

Citation Formats

Renzi, Ronald F., Sommer, Gregory J., Singh, Anup K., Hatch, Anson V., Claudnic, Mark R., Wang, Ying-Chih, and Van de Vreugde, James L.. Fluid delivery manifolds and microfluidic systems. United States: N. p., 2017. Web.
Renzi, Ronald F., Sommer, Gregory J., Singh, Anup K., Hatch, Anson V., Claudnic, Mark R., Wang, Ying-Chih, & Van de Vreugde, James L.. Fluid delivery manifolds and microfluidic systems. United States.
Renzi, Ronald F., Sommer, Gregory J., Singh, Anup K., Hatch, Anson V., Claudnic, Mark R., Wang, Ying-Chih, and Van de Vreugde, James L.. Tue . "Fluid delivery manifolds and microfluidic systems". United States. doi:. https://www.osti.gov/servlets/purl/1345393.
@article{osti_1345393,
title = {Fluid delivery manifolds and microfluidic systems},
author = {Renzi, Ronald F. and Sommer, Gregory J. and Singh, Anup K. and Hatch, Anson V. and Claudnic, Mark R. and Wang, Ying-Chih and Van de Vreugde, James L.},
abstractNote = {Embodiments of fluid distribution manifolds, cartridges, and microfluidic systems are described herein. Fluid distribution manifolds may include an insert member and a manifold base and may define a substantially closed channel within the manifold when the insert member is press-fit into the base. Cartridges described herein may allow for simultaneous electrical and fluidic interconnection with an electrical multiplex board and may be held in place using magnetic attraction.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Feb 28 00:00:00 EST 2017},
month = {Tue Feb 28 00:00:00 EST 2017}
}

Patent:

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  • A microfabricated device and method for proportioning and mixing electrokinetically manipulated biological or chemical materials is disclosed. The microfabricated device mixes a plurality of materials in volumetric proportions controlled by the electrical resistances of tributary reagent channels through which the materials are transported. The microchip includes two or more tributary reagent channels combining at one or more junctions to form one or more mixing channels. By varying the geometries of the channels (length, cross section, etc.), a plurality of reagent materials can be mixed at a junction such that the proportions of the reagent materials in the mixing channel dependmore » on a ratio of the channel geometries and material properties. Such an approach facilitates voltage division on the microchip without relying on external wiring schemes and voltage division techniques external to the microchip. Microchannel designs that provide the necessary voltage division to accomplish electrokinetic valving operations using a single voltage source and a switch are also described. In addition, microchannel designs that accomplish fluidic operation utilizing a minimal number of fluidic reservoirs are disclosed.« less
  • A microfabricated device and method for proportioning and mixing electrokinetically manipulated biological or chemical materials is disclosed. The microfabricated device mixes a plurality of materials in volumetric proportions controlled by the electrical resistances of tributary reagent channels through which the materials are transported. The microchip includes two or more tributary reagent channels combining at one or more junctions to form one or more mixing channels. By varying the geometries of the channels (length, cross section, etc.), a plurality of reagent materials can be mixed at a junction such that the proportions of the reagent materials in the mixing channel dependmore » on a ratio of the channel geometries and material properties. Such an approach facilitates voltage division on the microchip without relying on external wiring schemes and voltage division techniques external to the microchip. Microchannel designs that provide the necessary voltage division to accomplish electrokinetic valving operations using a single voltage source and a switch are also described. In addition, microchannel designs that accomplish fluidic operation utilizing a minimal number of fluidic reservoirs are disclosed.« less
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