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Title: Magnetic microscopic imaging with an optically pumped magnetometer and flux guides

Journal Article · · Applied Physics Letters
DOI:https://doi.org/10.1063/1.4975069· OSTI ID:1344366

By combining an optically pumped magnetometer (OPM) with flux guides (FGs) and by installing a sample platform on automated translation stages, we have implemented an ultra-sensitive FG-OPM scanning magnetic imaging system that is capable of detecting magnetic fields of ∼20 pT with spatial resolution better than 300 μm (expected to reach ∼10 pT sensitivity and ∼100 μm spatial resolution with optimized FGs). As a demonstration of one possible application of the FG-OPM device, we conducted magnetic imaging of micron-size magnetic particles. Magnetic imaging of such particles, including nano-particles and clusters, is very important for many fields, especially for medical cancer diagnostics and biophysics applications. For rapid, precise magnetic imaging, we constructed an automatic scanning system, which holds and moves a target sample containing magnetic particles at a given stand-off distance from the FG tips. We show that the device was able to produce clear microscopic magnetic images of 10 μm-size magnetic particles. In addition, we also numerically investigated how the magnetic flux from a target sample at a given stand-off distance is transmitted to the OPM vapor cell.

Research Organization:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Sponsoring Organization:
USDOE Laboratory Directed Research and Development (LDRD) Program
Grant/Contract Number:
AC52-06NA25396; 20150300ER
OSTI ID:
1344366
Alternate ID(s):
OSTI ID: 1985541
Report Number(s):
LA-UR-16-28672; TRN: US1700944
Journal Information:
Applied Physics Letters, Vol. 110, Issue 4; ISSN 0003-6951
Publisher:
American Institute of Physics (AIP)Copyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 9 works
Citation information provided by
Web of Science

References (11)

A subfemtotesla multichannel atomic magnetometer journal April 2003
Magnetic relaxometry with an atomic magnetometer and SQUID sensors on targeted cancer cells journal August 2012
Development of a SQUID-Based ${}^{3}\hbox{He}$ Co-Magnetometer Readout for a Neutron Electric Dipole Moment Experiment journal June 2013
Non-invasive detection of animal nerve impulses with an atomic magnetometer operating near quantum limited sensitivity journal July 2016
Optical magnetometry journal April 2007
Optical brain imaging in vivo: techniques and applications from animal to man journal January 2007
Ultra-sensitive Magnetic Microscopy with an Optically Pumped Magnetometer journal April 2016
Permanent Magnet Materials and their Application book January 2012
Search for exotic spin-dependent interactions with a spin-exchange relaxation-free magnetometer journal August 2016
New experimental limit on the electric dipole moment of the electron in a paramagnetic insulator journal May 2015
The “Shim-a-ring” magnet: Configurable static magnetic fields using a ring magnet with a concentric ferromagnetic shim journal May 2013

Cited By (3)

Measurement of the spatial magnetic field distribution in a single large spin-exchange relaxation-free vapor cell journal January 2019
Nondestructive in-line sub-picomolar detection of magnetic nanoparticles in flowing complex fluids journal February 2018
Nondestructive in-line sub-picomolar detection of magnetic nanoparticles in flowing complex fluids text January 2018

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