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Title: The Texas A&M Radioisotope Production and Radiochemistry Program

Abstract

The main motivation of the project at Texas A&M University was to carry out the production of critically needed radioisotopes used in medicine for diagnostics and therapy, and to establish an academic program in radionuclide production and separation methods. After a lengthy battle with the Texas A&M University Radiation Safety Office, the Texas Department of State Health Services granted us a license for the production of radionuclides in July 2015, allowing us to work in earnest in our project objectives. Experiments began immediately after licensing, and we started the assembly and testing of our target systems. There were four analytical/theoretical projects and two experimental target systems. These were for At-211 production and for Zn-62/Cu-62 production. The theoretical projects were related to the production of Mo-99/Tc-99m using a) a subcritical aqueous target system and b) production of Tc-99m from accelerator-generated Mo-99 utilizing a photon-neutron interaction with enriched Mo-100 targets. The two experimental projects were the development of targetry systems and production of At-211 and Zn-62/Cu-62 generator. The targetry system for At-211 has been tested and production of At-211 is chronic depending of availability of beam time at the cyclotron. The installation and testing of the targetry system for the production ofmore » Zn-62/Cu-62 has not been finalized. A description of the systems is described. The academic program in radionuclide production and separation methods was initiated in the fall of 2011 and, due to the lack of a radiochemistry laboratory, it was suspended. We expect to re-start the academic program at the Texas A&M Institute for Preclinical Studies under the Molecular Imaging Program.« less

Authors:
ORCiD logo [1]
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  1. Texas A & M Univ., College Station, TX (United States). Dept. of Nuclear Engineering. Dept. of Veterinary Integrative Biosciences
Publication Date:
Research Org.:
Texas A & M Univ., College Station, TX (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1333562
Report Number(s):
DE-SC0007371
TRN: US1700768
DOE Contract Number:
SC0007371
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; 43 PARTICLE ACCELERATORS; COPPER 62; ASTATINE 211; TECHNETIUM 99; ZINC 62; MOLYBDENUM 99; BIOMEDICAL RADIOGRAPHY; TEXAS; PHOTONUCLEAR REACTIONS; RADIOCHEMISTRY; PHOTONEUTRONS; MOLYBDENUM 100 TARGET; ISOTOPE PRODUCTION; TESTING; TARGETS; RADIOPHARMACEUTICALS; At-211; Mo-99/Tc-99m; Zn-62/Cu-62

Citation Formats

Akabani, Gamal. The Texas A&M Radioisotope Production and Radiochemistry Program. United States: N. p., 2016. Web. doi:10.2172/1333562.
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Akabani, Gamal. The Texas A&M Radioisotope Production and Radiochemistry Program. United States. doi:10.2172/1333562.
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Akabani, Gamal. Fri . "The Texas A&M Radioisotope Production and Radiochemistry Program". United States. doi:10.2172/1333562. https://www.osti.gov/servlets/purl/1333562.
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@article{osti_1333562,
title = {The Texas A&M Radioisotope Production and Radiochemistry Program},
author = {Akabani, Gamal},
abstractNote = {The main motivation of the project at Texas A&M University was to carry out the production of critically needed radioisotopes used in medicine for diagnostics and therapy, and to establish an academic program in radionuclide production and separation methods. After a lengthy battle with the Texas A&M University Radiation Safety Office, the Texas Department of State Health Services granted us a license for the production of radionuclides in July 2015, allowing us to work in earnest in our project objectives. Experiments began immediately after licensing, and we started the assembly and testing of our target systems. There were four analytical/theoretical projects and two experimental target systems. These were for At-211 production and for Zn-62/Cu-62 production. The theoretical projects were related to the production of Mo-99/Tc-99m using a) a subcritical aqueous target system and b) production of Tc-99m from accelerator-generated Mo-99 utilizing a photon-neutron interaction with enriched Mo-100 targets. The two experimental projects were the development of targetry systems and production of At-211 and Zn-62/Cu-62 generator. The targetry system for At-211 has been tested and production of At-211 is chronic depending of availability of beam time at the cyclotron. The installation and testing of the targetry system for the production of Zn-62/Cu-62 has not been finalized. A description of the systems is described. The academic program in radionuclide production and separation methods was initiated in the fall of 2011 and, due to the lack of a radiochemistry laboratory, it was suspended. We expect to re-start the academic program at the Texas A&M Institute for Preclinical Studies under the Molecular Imaging Program.},
doi = {10.2172/1333562},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Fri Oct 28 00:00:00 EDT 2016},
month = {Fri Oct 28 00:00:00 EDT 2016}
}
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Technical Report:
View Technical Report (9.06 MB)
DOI:  10.2172/1333562
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  • The main motivation of the project at Texas A&M University was to carry out the production of critically needed radioisotopes used in medicine for diagnostic and therapy, and to establish an academic program in radionuclide production and separation methods. After a lengthy battle with the Texas A&M University Radiation Safety Office, the Texas Department of State Health Services granted us a license for the production of radionuclides in July 2015, allowing us to work in earnest in our project objectives. Experiments began immediately after licensing, and we started the assembly and testing of our target systems. There were four analytical/theoreticalmore » projects and two experimental target systems. These were for At-211 production and for Zn- 62/Cu-62 production. The theoretical projects were related to the production of Mo-99/Tc-99m using (a) a subcritical aqueous target system and (b) production of Tc-99m from accelerator-generated Mo-99 utilizing a photon-neutron interaction with enriched Mo-100 targets. The two experimental projects were the development of targetry systems and production of At-211 and Zn-62/Cu-62 generator. The targetry system for At-211 has been tested and production of At-211 is chronic depending of availability of beam time at the cyclotron. The installation and testing of the targetry system for the production of Zn-62/Cu-62 has not been finalized. A description of the systems is described. The academic program in radionuclide production and separation methods was initiated in the fall of 2011; due to the lack of a radiochemistry laboratory, it was suspended. We expect to re-start the academic program at the Texas A&M Institute for Preclinical Studies under the Molecular Imaging Program.« less

  • A separate abstract was prepared for each of the two sections of the report. (TFD)

  • ;
    The High-Energy Group at Texas A and M has continued to strengthen and grow during this the first full year of funding from the Department of Energy. The past year was marked by several successes: (a) the funding of our group's GUT monopole search, (b) the construction and testing of a prototype hadron calorimeter for the Fermilab Collider Detector, (c) a preliminary agreement on our group's responsibilities for the Fermilab Collider Detector, and (d) the beginning of the assembly of the monopole detector at Avery Island, Louisiana. The accompanying progress report will detail the progress being made by our groupmore » in these areas over the past year. In addition, future plans and funding requests for continued DOE support for the period April 1, 1983 to March 31, 1984, are presented.« less

  • The experimental and theoretical high energy physics programs at Texas A and M University have continued their ambitious research activities over the past year. On the experimental side, the authors have continued their participation in two major operating experiments, CDF and MACRO, and each of these programs have attained significant milestones during this period. Especially note worthy is the CDF Collaborations paper on the ``evidence`` for the top quark and MACRO`s completion of the construction of the ``Attico``. In CDF, the Texas A and M group continues to play a leading role in the plans for upgrading the silicon vertexmore » detector, as well as supporting the on going running of this experiment during its current data taking run. In addition, the group has focused its analysis efforts on studies of trilepton events and as well searching for supersymmetric particles. In MACRO, the authors have continued their work on the development of the final version of the wave form digitizing system. Within the past month the final production circuits have been assembled and they are currently testing these units at Texas A and M. The authors plan to complete this testing and commission the wave form digitizing system on the MACRO detector by the end of 1994. The theoretical high energy physics program has also continued to develop during the past funding cycle. D. Nanopoulos and colleagues have continued the study of their very successful string-derived model that unifies all known interactions; flipped SU(5), which is the leading candidate for a theory of everything. C. Pope has continued his work on generalizations of the symmetries of string theory, known as W algebras.« less

  • The experimental and theoretical high energy physics programs at Texas A&M University have continued their vigorous research activities over the past year. This is the final report on activities which have been supported through DOE grant DE-FG05-91ER40633. This report covers the period January 1, 1995 to December 31, 1995. The project includes a component which has used the Fermilab Tevatron, as part of the Collider Detector (CDF) collaboration. They have been involved in operations and theory work on supersymmetry (SUSY). Another component works with the MACRO experiment at the Gran Sasso Laboratory in l`Aquila, Italy, to study magnetic monopoles, astrophysicalmore » neutrinos, and cosmic ray phenomena. A third effort has been involved in developing an Expression of Interest and a Fermilab proposal for a large fine-grained magnetic sampling detector to be used for studying events inducted by accelerator or atmospheric neutrinos as a way to search for neutrino oscillations (MINOS). Finally the theoretical effort has addressed string theory, model building, SUSY phenomenology, astroparticle physics, and brain function and quantum mechanics.« less