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Title: Identification of cancer protein biomarkers using proteomic techniques

Abstract

The claimed invention describes methods to diagnose or aid in the diagnosis of cancer. The claimed methods are based on the identification of biomarkers which are particularly well suited to discriminate between cancer subjects and healthy subjects. These biomarkers were identified using a unique and novel screening method described herein. The biomarkers identified herein can also be used in the prognosis and monitoring of cancer. The invention comprises the use of leptin, prolactin, OPN and IGF-II for diagnosing, prognosis and monitoring of ovarian cancer.

Inventors:
; ;
Publication Date:
Research Org.:
Yale Univ., New Haven, CT (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1329309
Patent Number(s):
9,470,688
Application Number:
14/602,916
Assignee:
Yale University (New Haven, CT CHO
DOE Contract Number:  
FG02-ER63462
Resource Type:
Patent
Resource Relation:
Patent File Date: 2015 Jul 22
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES

Citation Formats

Mor, Gil G., Ward, David C., and Bray-Ward, Patricia. Identification of cancer protein biomarkers using proteomic techniques. United States: N. p., 2016. Web.
Mor, Gil G., Ward, David C., & Bray-Ward, Patricia. Identification of cancer protein biomarkers using proteomic techniques. United States.
Mor, Gil G., Ward, David C., and Bray-Ward, Patricia. Tue . "Identification of cancer protein biomarkers using proteomic techniques". United States. doi:. https://www.osti.gov/servlets/purl/1329309.
@article{osti_1329309,
title = {Identification of cancer protein biomarkers using proteomic techniques},
author = {Mor, Gil G. and Ward, David C. and Bray-Ward, Patricia},
abstractNote = {The claimed invention describes methods to diagnose or aid in the diagnosis of cancer. The claimed methods are based on the identification of biomarkers which are particularly well suited to discriminate between cancer subjects and healthy subjects. These biomarkers were identified using a unique and novel screening method described herein. The biomarkers identified herein can also be used in the prognosis and monitoring of cancer. The invention comprises the use of leptin, prolactin, OPN and IGF-II for diagnosing, prognosis and monitoring of ovarian cancer.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 18 00:00:00 EDT 2016},
month = {Tue Oct 18 00:00:00 EDT 2016}
}

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Works referenced in this record:

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