skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Decoding how a soil bacterium extracts building blocks and metabolic energy from ligninolysis provides road map for lignin valorization (Towards Lignin valorization: How a soil bacterium extracts building blocks and metabolic energy from "Lignolysis")

Abstract

Lignin is a major resources for the production of next generation renewable aromatics. Sphingobium sp. SYK-6 is a bacterium that has been well-studied for the breakdown of lignin-derived compounds. There has been a lot of interest in SYK-6 lignolytic activity and many recent works have focused on understanding the unique catabolic pathway it possesses for the degradation of lignin derived monomers and oligomers. Furthermore, there has been no prior effort in understanding the central fluxome based on lignin derived substrates into value-added chemicals.

Authors:
 [1];  [2];  [1];  [1];  [1];  [1];  [2];  [3]
  1. Sandia National Lab. (SNL-CA), Livermore, CA (United States)
  2. Washington Univ., St. Louis, MO (United States). Environmental and Chemical Engineering
  3. Sandia National Lab. (SNL-CA), Livermore, CA (United States); Univ. of Minnesota, St. Paul, MN (United States). Dept. of Bioproducts and Biosystems Engineering
Publication Date:
Research Org.:
Sandia National Lab. (SNL-CA), Livermore, CA (United States)
Sponsoring Org.:
USDOE National Nuclear Security Administration (NNSA)
OSTI Identifier:
1325317
Alternate Identifier(s):
OSTI ID: 1239396
Report Number(s):
SAND-2016-0538J
Journal ID: ISSN 0027-8424; 618709; TRN: US1700133
Grant/Contract Number:  
AC04-94AL85000; 16-0758
Resource Type:
Journal Article: Published Article
Journal Name:
Proceedings of the National Academy of Sciences of the United States of America
Additional Journal Information:
Journal Volume: 113; Journal Issue: 40; Journal ID: ISSN 0027-8424
Publisher:
National Academy of Sciences, Washington, DC (United States)
Country of Publication:
United States
Language:
English
Subject:
09 BIOMASS FUELS; 60 APPLIED LIFE SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 13C-MFA; fingerprinting; gluconeogenesis; NADPH; TCA

Citation Formats

Varman, Arul M., He, Lian, Follenfant, Rhiannon, Wu, Weihua, Wemmer, Sarah, Wrobel, Steven A., Tang, Yinjie J., and Singh, Seema. Decoding how a soil bacterium extracts building blocks and metabolic energy from ligninolysis provides road map for lignin valorization (Towards Lignin valorization: How a soil bacterium extracts building blocks and metabolic energy from "Lignolysis"). United States: N. p., 2016. Web. doi:10.1073/pnas.1606043113.
Varman, Arul M., He, Lian, Follenfant, Rhiannon, Wu, Weihua, Wemmer, Sarah, Wrobel, Steven A., Tang, Yinjie J., & Singh, Seema. Decoding how a soil bacterium extracts building blocks and metabolic energy from ligninolysis provides road map for lignin valorization (Towards Lignin valorization: How a soil bacterium extracts building blocks and metabolic energy from "Lignolysis"). United States. doi:10.1073/pnas.1606043113.
Varman, Arul M., He, Lian, Follenfant, Rhiannon, Wu, Weihua, Wemmer, Sarah, Wrobel, Steven A., Tang, Yinjie J., and Singh, Seema. Thu . "Decoding how a soil bacterium extracts building blocks and metabolic energy from ligninolysis provides road map for lignin valorization (Towards Lignin valorization: How a soil bacterium extracts building blocks and metabolic energy from "Lignolysis")". United States. doi:10.1073/pnas.1606043113.
@article{osti_1325317,
title = {Decoding how a soil bacterium extracts building blocks and metabolic energy from ligninolysis provides road map for lignin valorization (Towards Lignin valorization: How a soil bacterium extracts building blocks and metabolic energy from "Lignolysis")},
author = {Varman, Arul M. and He, Lian and Follenfant, Rhiannon and Wu, Weihua and Wemmer, Sarah and Wrobel, Steven A. and Tang, Yinjie J. and Singh, Seema},
abstractNote = {Lignin is a major resources for the production of next generation renewable aromatics. Sphingobium sp. SYK-6 is a bacterium that has been well-studied for the breakdown of lignin-derived compounds. There has been a lot of interest in SYK-6 lignolytic activity and many recent works have focused on understanding the unique catabolic pathway it possesses for the degradation of lignin derived monomers and oligomers. Furthermore, there has been no prior effort in understanding the central fluxome based on lignin derived substrates into value-added chemicals.},
doi = {10.1073/pnas.1606043113},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
issn = {0027-8424},
number = 40,
volume = 113,
place = {United States},
year = {2016},
month = {9}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record at 10.1073/pnas.1606043113

Citation Metrics:
Cited by: 9 works
Citation information provided by
Web of Science

Save / Share:

Works referenced in this record:

Lignin modification improves fermentable sugar yields for biofuel production
journal, June 2007

  • Chen, Fang; Dixon, Richard A.
  • Nature Biotechnology, Vol. 25, Issue 7, p. 759-761
  • DOI: 10.1038/nbt1316

Metabolic Flux Analysis of the Mixotrophic Metabolisms in the Green Sulfur Bacterium Chlorobaculum tepidum
journal, October 2010

  • Feng, Xueyang; Tang, Kuo-Hsiang; Blankenship, Robert E.
  • Journal of Biological Chemistry, Vol. 285, Issue 50, p. 39544-39550
  • DOI: 10.1074/jbc.M110.162958

Lignin valorization through integrated biological funneling and chemical catalysis
journal, August 2014

  • Linger, J. G.; Vardon, D. R.; Guarnieri, M. T.
  • Proceedings of the National Academy of Sciences, Vol. 111, Issue 33, p. 12013-12018
  • DOI: 10.1073/pnas.1410657111

Lignin Valorization: Improving Lignin Processing in the Biorefinery
journal, May 2014

  • Ragauskas, A. J.; Beckham, G. T.; Biddy, M. J.
  • Science, Vol. 344, Issue 6185, p. 1246843-1246843
  • DOI: 10.1126/science.1246843

Valorization of Biomass: Deriving More Value from Waste
journal, August 2012


Pathways for degradation of lignin in bacteria and fungi
journal, January 2011

  • Bugg, Timothy D. H.; Ahmad, Mark; Hardiman, Elizabeth M.
  • Natural Product Reports, Vol. 28, Issue 12, p. 1883-1896
  • DOI: 10.1039/c1np00042j

Loosening lignin's grip on biofuel production
journal, July 2007

  • Chapple, Clint; Ladisch, Michael; Meilan, Rick
  • Nature Biotechnology, Vol. 25, Issue 7, p. 746-748
  • DOI: 10.1038/nbt0707-746

Formic-acid-induced depolymerization of oxidized lignin to aromatics
journal, November 2014

  • Rahimi, Alireza; Ulbrich, Arne; Coon, Joshua J.
  • Nature, Vol. 515, Issue 7526, p. 249-252
  • DOI: 10.1038/nature13867

Biomass conversion: Lignin up for break-down
journal, December 2014

  • Bruijnincx, Pieter C. A.; Weckhuysen, Bert M.
  • Nature Chemistry, Vol. 6, Issue 12, p. 1035-1036
  • DOI: 10.1038/nchem.2120

Lignin depolymerisation strategies: towards valuable chemicals and fuels
journal, January 2014

  • Xu, Chunping; Arancon, Rick Arneil D.; Labidi, Jalel
  • Chemical Society Reviews, Vol. 43, Issue 22, p. 7485-7500
  • DOI: 10.1039/C4CS00235K

Monolignol Ferulate Transferase Introduces Chemically Labile Linkages into the Lignin Backbone
journal, April 2014


A Tetrahydrofolate-Dependent O-Demethylase, LigM, Is Crucial for Catabolism of Vanillate and Syringate in Sphingomonas paucimobilis SYK-6
journal, March 2005