U.S. Department of EnergyOffice of Scientific and Technical Information
Organic Polymer Chemistry in the Context of Novel Processes
Abstract
This paper was written to shed light on a series of what some have stated are not so obvious connections that link polymer synthesis in supercritical CO2 to cancer treatment and vaccines, nonflammable polymer electrolytes for lithium ion batteries, and 3D printing. In telling this story, we also attempt to show the value of versatility in applying one’s primary area of expertise to address pertinent questions in science and in society. In this Outlook, we attempted to identify key factors to enable a versatile and nimble research effort to take shape in an effort to influence diverse fields and have a tangible impact in the private sector through the translation of discoveries into the marketplace.
- Authors:
-
- Chemistry Department, University of North Carolina, Chapel Hill, North Carolina 27599, United States, Chemical Engineering Department, North Carolina State University, Raleigh, North Carolina 27695, United States, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599, United States
- Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599, United States
- Publication Date:
- Research Org.:
- University of North Carolina, Chapel Hill, NC (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES); National Science Foundation (NSF); National Institutes of Health (NIH); US Department of the Navy, Office of Naval Research (ONR)
- OSTI Identifier:
- 1324361
- Alternate Identifier(s):
- OSTI ID: 1337512
- Grant/Contract Number:
- A15-0871-001; SC0012673; A15-0871- 001; A15-580-001; CHE-9876674; 1DP1OD006432; U54CA198999; U54CA119373; U54CA151652; N000014-02-1-0185; N00014-07-1-0260; N00014- 07-1-02612
- Resource Type:
- Journal Article: Published Article
- Journal Name:
- ACS Central Science
- Additional Journal Information:
- Journal Name: ACS Central Science Journal Volume: 2 Journal Issue: 9; Journal ID: ISSN 2374-7943
- Publisher:
- American Chemical Society
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 36 MATERIALS SCIENCE; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
DeSimone, Joseph M., Mecham, Sue J., and Farrell, Crista L. Organic Polymer Chemistry in the Context of Novel Processes. United States: N. p., 2016.
Web. doi:10.1021/acscentsci.6b00195.
DeSimone, Joseph M., Mecham, Sue J., & Farrell, Crista L. Organic Polymer Chemistry in the Context of Novel Processes. United States. https://doi.org/10.1021/acscentsci.6b00195
DeSimone, Joseph M., Mecham, Sue J., and Farrell, Crista L. 2016.
"Organic Polymer Chemistry in the Context of Novel Processes". United States. https://doi.org/10.1021/acscentsci.6b00195.
@article{osti_1324361,
title = {Organic Polymer Chemistry in the Context of Novel Processes},
author = {DeSimone, Joseph M. and Mecham, Sue J. and Farrell, Crista L.},
abstractNote = {This paper was written to shed light on a series of what some have stated are not so obvious connections that link polymer synthesis in supercritical CO2 to cancer treatment and vaccines, nonflammable polymer electrolytes for lithium ion batteries, and 3D printing. In telling this story, we also attempt to show the value of versatility in applying one’s primary area of expertise to address pertinent questions in science and in society. In this Outlook, we attempted to identify key factors to enable a versatile and nimble research effort to take shape in an effort to influence diverse fields and have a tangible impact in the private sector through the translation of discoveries into the marketplace.},
doi = {10.1021/acscentsci.6b00195},
url = {https://www.osti.gov/biblio/1324361},
journal = {ACS Central Science},
issn = {2374-7943},
number = 9,
volume = 2,
place = {United States},
year = {Tue Sep 13 00:00:00 EDT 2016},
month = {Tue Sep 13 00:00:00 EDT 2016}
}
Free Publicly Available Full Text
Publisher's Version of Record at https://doi.org/10.1021/acscentsci.6b00195
Other availability
Search WorldCat to find libraries that may hold this journal
Cited by: 4 works
Citation information provided by
Web of Science
Web of Science
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Polymeric Nanogels Produced via Inverse Microemulsion Polymerization as Potential Gene and Antisense Delivery Agents
journal, December 2002
- McAllister, Karen; Sazani, Peter; Adam, Mirielle
- Journal of the American Chemical Society, Vol. 124, Issue 51
Direct Fabrication and Harvesting of Monodisperse, Shape-Specific Nanobiomaterials
journal, July 2005
- Rolland, Jason P.; Maynor, Benjamin W.; Euliss, Larken E.
- Journal of the American Chemical Society, Vol. 127, Issue 28
Photoinitiated Polymerization: Advances, Challenges, and Opportunities
journal, August 2010
- Yagci, Yusuf; Jockusch, Steffen; Turro, Nicholas J.
- Macromolecules, Vol. 43, Issue 15
Design of Nonionic Surfactants for Supercritical Carbon Dioxide
journal, December 1996
- McClain, J. B.; Betts, D. E.; Canelas, D. A.
- Science, Vol. 274, Issue 5295
Optically Transparent, Amphiphilic Networks Based on Blends of Perfluoropolyethers and Poly(ethylene glycol)
journal, October 2008
- Hu, Zhaokang; Chen, Liang; Betts, Douglas E.
- Journal of the American Chemical Society, Vol. 130, Issue 43
Hierarchical Inorganic-Organic Nanocomposites Possessing Amphiphilic and Morphological Complexities: Influence of Nanofiller Dispersion on Mechanical Performance
journal, September 2008
- Xu, Jinqi; Bartels, Jeremy W.; Bohnsack, David A.
- Advanced Functional Materials, Vol. 18, Issue 18
Nonflammable perfluoropolyether-based electrolytes for lithium batteries
journal, February 2014
- Wong, Dominica H. C.; Thelen, Jacob L.; Fu, Yanbao
- Proceedings of the National Academy of Sciences, Vol. 111, Issue 9
Solving the “World-to-Chip” Interface Problem with a Microfluidic Matrix
journal, September 2003
- Liu, Jian; Hansen, Carl; Quake, Stephen R.
- Analytical Chemistry, Vol. 75, Issue 18
Electrically Driven Alignment and Crystallization of Unique Anisotropic Polymer Particles
journal, July 2008
- Herlihy, Kevin P.; Nunes, Janine; DeSimone, Joseph M.
- Langmuir, Vol. 24, Issue 16
Strategies to Reduce Oxygen Inhibition in Photoinduced Polymerization
journal, September 2013
- Ligon, Samuel Clark; Husár, Branislav; Wutzel, Harald
- Chemical Reviews, Vol. 114, Issue 1
A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion
journal, December 2002
- Hansen, C. L.; Skordalakes, E.; Berger, J. M.
- Proceedings of the National Academy of Sciences, Vol. 99, Issue 26
The 'right' size in nanobiotechnology
journal, September 2003
- Whitesides, George M.
- Nature Biotechnology, Vol. 21, Issue 10
Self-Assembly of Phosphate Fluorosurfactants in Carbon Dioxide
journal, January 2004
- Keiper, Jason S.; Behles, Jacqueline A.; Bucholz, Tracy L.
- Langmuir, Vol. 20, Issue 4
Anti-Biofouling Properties of Comblike Block Copolymers with Amphiphilic Side Chains
journal, May 2006
- Krishnan, Sitaraman; Ayothi, Ramakrishnan; Hexemer, Alexander
- Langmuir, Vol. 22, Issue 11
Integrated nanoliter systems
journal, September 2003
- Hong, Jong Wook; Quake, Stephen R.
- Nature Biotechnology, Vol. 21, Issue 10
Compliant glass–polymer hybrid single ion-conducting electrolytes for lithium batteries
journal, December 2015
- Villaluenga, Irune; Wujcik, Kevin H.; Tong, Wei
- Proceedings of the National Academy of Sciences, Vol. 113, Issue 1
Rendering Protein-Based Particles Transiently Insoluble for Therapeutic Applications
journal, May 2012
- Xu, Jing; Wang, Jin; Luft, J. Christopher
- Journal of the American Chemical Society, Vol. 134, Issue 21
Scalable, Shape-Specific, Top-Down Fabrication Methods for the Synthesis of Engineered Colloidal Particles
journal, August 2010
- Merkel, Timothy J.; Herlihy, Kevin P.; Nunes, Janine
- Langmuir, Vol. 26, Issue 16
Review Article: Persistent organic pollutants and landfills - a review of past experiences and future challenges
journal, January 2011
- Weber, Roland; Watson, Alan; Forter, Martin
- Waste Management & Research: The Journal for a Sustainable Circular Economy, Vol. 29, Issue 1
High-Resolution Soft Lithography: Enabling Materials for Nanotechnologies
journal, November 2004
- Rolland, Jason P.; Hagberg, Erik C.; Denison, Ginger M.
- Angewandte Chemie International Edition, Vol. 43, Issue 43
Diffusion and mass transfer in supercritical fluids
journal, December 1986
- Debenedetti, P. G.; Reid, R. C.
- AIChE Journal, Vol. 32, Issue 12
The effect of particle design on cellular internalization pathways
journal, August 2008
- Gratton, S. E. A.; Ropp, P. A.; Pohlhaus, P. D.
- Proceedings of the National Academy of Sciences, Vol. 105, Issue 33, p. 11613-11618
Homogeneous and multiphase poly(methyl methacrylate) graft polymers via the macromonomer method
journal, February 1990
- Desimone, J. M.; Hellstern, A. M.; Siochi, E. J.
- Makromolekulare Chemie. Macromolecular Symposia, Vol. 32, Issue 1
Fluorocarbon-Based Heterophase Polymeric Materials. 1. Block Copolymer Surfactants for Carbon Dioxide Applications
journal, September 1994
- Guan, Zhibin; DeSimone, J. M.
- Macromolecules, Vol. 27, Issue 20
Driving Convergence with Human Diversity
journal, May 2014
- DeSimone, J. M.; Farrell, C. L.
- Science Translational Medicine, Vol. 6, Issue 238
The Pursuit of a Scalable Nanofabrication Platform for Use in Material and Life Science Applications
journal, August 2008
- Gratton, Stephanie E. A.; Williams, Stuart S.; Napier, Mary E.
- Accounts of Chemical Research, Vol. 41, Issue 12
A microfabricated fluorescence-activated cell sorter
journal, November 1999
- Fu, Anne Y.; Spence, Charles; Scherer, Axel
- Nature Biotechnology, Vol. 17, Issue 11
Surface engineering of styrene/PEGylated-fluoroalkyl styrene block copolymer thin films: Block Copolymer Thin Films
journal, November 2008
- Martinelli, Elisa; Menghetti, Sara; Galli, Giancarlo
- Journal of Polymer Science Part A: Polymer Chemistry, Vol. 47, Issue 1
Solvent-Resistant Photocurable “Liquid Teflon” for Microfluidic Device Fabrication
journal, March 2004
- Rolland, Jason P.; Van Dam, R. Michael; Schorzman, Derek A.
- Journal of the American Chemical Society, Vol. 126, Issue 8, p. 2322-2323
Aggregation of Amphiphilic Molecules in Supercritical Carbon Dioxide: A Small Angle X-ray Scattering Study
journal, November 1995
- Fulton, John L.; Pfund, David M.; McClain, J. B.
- Langmuir, Vol. 11, Issue 11
Synthesis of Tetrafluoroethylene-Based, Nonaqueous Fluoropolymers in Supercritical Carbon Dioxide
journal, November 1995
- Romack, T. J.; DeSimone, J. M.; Treat, T. A.
- Macromolecules, Vol. 28, Issue 24
Single-Step Fabrication of Computationally Designed Microneedles by Continuous Liquid Interface Production
journal, September 2016
- Johnson, Ashley R.; Caudill, Cassie L.; Tumbleston, John R.
- PLOS ONE, Vol. 11, Issue 9
Novel supercritical fluid techniques for polymer fractionation and purification: 2. Fractionation and characterization of functional siloxane oligomers
journal, December 1984
- Yilg�r, Iskender; McGrath, James E.
- Polymer Bulletin, Vol. 12, Issue 6
Perfluoropolyether Synthesis in Liquid Carbon Dioxide by Hexafluoropropylene Photooxidation
journal, November 1999
- Bunyard, W. Clayton; Romack, Timothy J.; DeSimone, Joseph M.
- Macromolecules, Vol. 32, Issue 24
Novel supercritical fluid techniques for polymer fractionation and purification: 1. Background
journal, December 1984
- Yilg�r, Iskender; McGrath, James E.
- Polymer Bulletin, Vol. 12, Issue 6
From The Cover: Systematic investigation of protein phase behavior with a microfluidic formulator
journal, September 2004
- Hansen, C. L.; Sommer, M. O. A.; Quake, S. R.
- Proceedings of the National Academy of Sciences, Vol. 101, Issue 40, p. 14431-14436
Fluoropolymer synthesis in supercritical carbon dioxide
journal, January 2009
- Du, Libin; Kelly, Jennifer Y.; Roberts, George W.
- The Journal of Supercritical Fluids, Vol. 47, Issue 3
Continuous liquid interface production of 3D objects
journal, March 2015
- Tumbleston, J. R.; Shirvanyants, D.; Ermoshkin, N.
- Science, Vol. 347, Issue 6228
Synthesis of Fluoropolymers in Supercritical Carbon Dioxide
journal, August 1992
- DeSimone, J. M.; Guan, Z.; Elsbernd, C. S.
- Science, Vol. 257, Issue 5072
Hyperbranched Fluoropolymers and their Hybridization into Complex Amphiphilic Crosslinked Copolymer Networks
journal, August 2007
- Bartels, Jeremy W.; Cheng, Chong; Powell, Kenya T.
- Macromolecular Chemistry and Physics, Vol. 208, Issue 15
A review on stereolithography and its applications in biomedical engineering
journal, August 2010
- Melchels, Ferry P. W.; Feijen, Jan; Grijpma, Dirk W.
- Biomaterials, Vol. 31, Issue 24
Extraction of a hydrophilic compound from water into liquid CO2 using dendritic surfactants
journal, September 1997
- Cooper, A. I.; Londono, J. D.; Wignall, G.
- Nature, Vol. 389, Issue 6649
Future of the Particle Replication in Nonwetting Templates (PRINT) Technology
journal, May 2013
- Xu, Jing; Wong, Dominica H. C.; Byrne, James D.
- Angewandte Chemie International Edition, Vol. 52, Issue 26