Ordering in bio-inorganic hybrid nanomaterials probed by in situ scanning transmission X-ray microscopy

Lee, Jonathan R. I.; Bagge-Hansen, Michael; Tunuguntla, Ramya; Kim, Kyunghoon; Bangar, Mangesh; Willey, Trevor M.; Tran, Ich C.; Kilcoyne, David A.; Noy, Aleksandr; van Buuren, Tony

doi:10.1039/C5NR00622H

Title: Ordering in bio-inorganic hybrid nanomaterials probed by in situ scanning transmission X-ray microscopy

Journal Article · Wed Apr 15 00:00:00 EDT 2015 · Nanoscale

DOI:https://doi.org/10.1039/C5NR00622H· OSTI ID:1313546

Lee, Jonathan R. I. ^[1]; Bagge-Hansen, Michael ^[1]; Tunuguntla, Ramya ^[1]; Kim, Kyunghoon ^[2]; Bangar, Mangesh ^[3]; Willey, Trevor M. ^[1]; Tran, Ich C. ^[1]; Kilcoyne, David A. ^[3]; Noy, Aleksandr ^[1]; van Buuren, Tony ^[1]

Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Univ. of California, Berkeley, CA (United States)
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

Here, phospholipid bilayer coated Si nanowires are one-dimensional (1D) composites that provide versatile bio-nanoelectronic functionality via incorporation of a wide variety of biomolecules into the phospholipid matrix. The physiochemical behaviour of the phospholipid bilayer is strongly dependent on its structure and, as a consequence, substantial modelling and experimental efforts have been directed at the structural characterization of supported bilayers and unsupported phospholipid vesicles; nonetheless, the experimental studies conducted to date have exclusively involved volume-averaged techniques, which do not allow for the assignment of spatially resolved structural variations that could critically impact the performance of the 1D phospholipid-Si NW composites. In this manuscript, we use scanning transmission X-ray microscopy (STXM) to probe bond orientation and bilayer thickness as a function of position with a spatial resolution of ~30 nm for Δ9-cis 1,2-dioleoyl-sn-glycero-3-phosphocholine layers prepared Si NWs. When coupled with small angle X-ray scattering measurements, the STXM data reveal structural motifs of the Si NWs that give rise to multi-bilayer formation and enable assignment of the orientation of specific bonds known to affect the order and rigidity of phospholipid bilayers.

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Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Organization:: USDOE

Grant/Contract Number:: AC52-07NA27344

OSTI ID:: 1313546

Report Number(s):: LLNL-JRNL-663215; NANOHL

Journal Information:: Nanoscale, Vol. 7, Issue 21; ISSN 2040-3364

Publisher:: Royal Society of ChemistryCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 2 works

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