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Title: Peptide and protein biomarkers for type 1 diabetes mellitus

Abstract

A method for identifying persons with increased risk of developing type 1 diabetes mellitus, or having type I diabetes mellitus, utilizing selected biomarkers described herein either alone or in combination. The present disclosure allows for broad based, reliable, screening of large population bases. Also provided are arrays and kits that can be used to perform such methods.

Inventors:
;
Publication Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1311866
Patent Number(s):
9,429,569
Application Number:
14/268,002
Assignee:
Battelle Memorial Institute (Richland, WA) PNNL
DOE Contract Number:  
AC05-76RL01830
Resource Type:
Patent
Resource Relation:
Patent File Date: 2014 May 02
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Zhang, Qibin, and Metz, Thomas O. Peptide and protein biomarkers for type 1 diabetes mellitus. United States: N. p., 2016. Web.
Zhang, Qibin, & Metz, Thomas O. Peptide and protein biomarkers for type 1 diabetes mellitus. United States.
Zhang, Qibin, and Metz, Thomas O. Tue . "Peptide and protein biomarkers for type 1 diabetes mellitus". United States. https://www.osti.gov/servlets/purl/1311866.
@article{osti_1311866,
title = {Peptide and protein biomarkers for type 1 diabetes mellitus},
author = {Zhang, Qibin and Metz, Thomas O.},
abstractNote = {A method for identifying persons with increased risk of developing type 1 diabetes mellitus, or having type I diabetes mellitus, utilizing selected biomarkers described herein either alone or in combination. The present disclosure allows for broad based, reliable, screening of large population bases. Also provided are arrays and kits that can be used to perform such methods.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Aug 30 00:00:00 EDT 2016},
month = {Tue Aug 30 00:00:00 EDT 2016}
}

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Works referenced in this record:

Development of a fibrinogen-specific sandwich enzyme-linked immunosorbent assay microarray assay for distinguishing between blood plasma and serum samples
journal, July 2011

  • Gonzalez, Rachel M.; Zhang, Qibin; Zangar, Richard C.
  • Analytical Biochemistry, Vol. 414, Issue 1, p. 99-102
  • DOI: 10.1016/j.ab.2011.02.039

Targeted proteomic strategy for clinical biomarker discovery
journal, December 2008