skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Modeling Transport in Gas Chromatography Columns for the Micro-ChemLab

Abstract

The gas chromatography (GC) column is a critical component in the microsystem for chemical detection ({mu}ChemLab{trademark}) being developed at Sandia. The goal is to etch a meter-long GC column onto a 1-cm{sup 2} silicon chip while maintaining good chromatographic performance. Our design strategy is to use a modeling and simulation approach. We have developed an analytical tool that models the transport and surface interaction process to achieve an optimized design of the GC column. This analytical tool has a flow module and a separation module. The flow module considers both the compressibility and slip flow effects that may significantly influence the gas transport in a long and narrow column. The separation module models analyte transport and physico-chemical interaction with the coated surface in the GC column. It predicts the column efficiency and performance. Results of our analysis will be presented in this paper. In addition to the analytical tool, we have also developed a time-dependent adsorption/desorption model and incorporated this model into a computational fluid dynamics (CFD) code to simulate analyte transport and separation process in GC columns. CFD simulations can capture the complex three-dimensional flow and transport dynamics, whereas the analytical tool cannot. Different column geometries have been studied,more » and results will be presented in this paper. Overall we have demonstrated that the modeling and simulation approach can guide the design of the GC column and will reduce the number of iterations in the device development.« less

Authors:
; ; ; ; ; ; ;
Publication Date:
Research Org.:
Sandia National Labs., Albuquerque, NM (US); Sandia National Labs., Livermore, CA (US)
Sponsoring Org.:
US Department of Energy (US)
OSTI Identifier:
13078
Report Number(s):
SAND99-2031C
TRN: AH200135%%267
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Conference
Resource Relation:
Conference: SPIE 1999 Symposium on Micromachining and Microfabrication/Microfluidic Devices, Santa Clara; CA (US), 09/21/1999--09/22/1999; Other Information: PBD: 1 Sep 1999
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 42 ENGINEERING; COMPRESSIBILITY; DESIGN; GAS CHROMATOGRAPHY; PERFORMANCE; COMPUTERIZED SIMULATION; SLIP FLOW; MASS TRANSFER; EXTRACTION COLUMNS; MINIATURIZATION; FLOW MODELS; FLUID MECHANICS; GAS CHROMATOGRAPH; ADSORPTION/DESORPTION; SEPARATION; MICROSCALE TRANSPORT; MICRO-CHEMLAB

Citation Formats

ADKINS,DOUGLAS R., FRYE-MASON,GREGORY CHARLES, HUDSON,MARY L., KOTTENSTETTE,RICHARD, MATZKE,CAROLYN M., SALINGER,ANDREW G., SHADID,JOHN N., and WONG, CHUNGNIN CHANN. Modeling Transport in Gas Chromatography Columns for the Micro-ChemLab. United States: N. p., 1999. Web.
ADKINS,DOUGLAS R., FRYE-MASON,GREGORY CHARLES, HUDSON,MARY L., KOTTENSTETTE,RICHARD, MATZKE,CAROLYN M., SALINGER,ANDREW G., SHADID,JOHN N., & WONG, CHUNGNIN CHANN. Modeling Transport in Gas Chromatography Columns for the Micro-ChemLab. United States.
ADKINS,DOUGLAS R., FRYE-MASON,GREGORY CHARLES, HUDSON,MARY L., KOTTENSTETTE,RICHARD, MATZKE,CAROLYN M., SALINGER,ANDREW G., SHADID,JOHN N., and WONG, CHUNGNIN CHANN. Wed . "Modeling Transport in Gas Chromatography Columns for the Micro-ChemLab". United States. https://www.osti.gov/servlets/purl/13078.
@article{osti_13078,
title = {Modeling Transport in Gas Chromatography Columns for the Micro-ChemLab},
author = {ADKINS,DOUGLAS R. and FRYE-MASON,GREGORY CHARLES and HUDSON,MARY L. and KOTTENSTETTE,RICHARD and MATZKE,CAROLYN M. and SALINGER,ANDREW G. and SHADID,JOHN N. and WONG, CHUNGNIN CHANN},
abstractNote = {The gas chromatography (GC) column is a critical component in the microsystem for chemical detection ({mu}ChemLab{trademark}) being developed at Sandia. The goal is to etch a meter-long GC column onto a 1-cm{sup 2} silicon chip while maintaining good chromatographic performance. Our design strategy is to use a modeling and simulation approach. We have developed an analytical tool that models the transport and surface interaction process to achieve an optimized design of the GC column. This analytical tool has a flow module and a separation module. The flow module considers both the compressibility and slip flow effects that may significantly influence the gas transport in a long and narrow column. The separation module models analyte transport and physico-chemical interaction with the coated surface in the GC column. It predicts the column efficiency and performance. Results of our analysis will be presented in this paper. In addition to the analytical tool, we have also developed a time-dependent adsorption/desorption model and incorporated this model into a computational fluid dynamics (CFD) code to simulate analyte transport and separation process in GC columns. CFD simulations can capture the complex three-dimensional flow and transport dynamics, whereas the analytical tool cannot. Different column geometries have been studied, and results will be presented in this paper. Overall we have demonstrated that the modeling and simulation approach can guide the design of the GC column and will reduce the number of iterations in the device development.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {9}
}

Conference:
Other availability
Please see Document Availability for additional information on obtaining the full-text document. Library patrons may search WorldCat to identify libraries that hold this conference proceeding.

Save / Share: