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Title: Gold Nanoparticle Microwave Synthesis

Abstract

At the nanometer scale, numerous compounds display different properties than those found in bulk material that can prove useful in areas such as medicinal chemistry. Gold nanoparticles, for example, display promise in newly developed hyperthermia therapies for cancer treatment. Currently, gold nanoparticle synthesis is performed via the hot injection technique which has large variability in final particle size and a longer reaction time. One underdeveloped area by which these particles could be produced is through microwave synthesis. To initiate heating, microwaves agitate polar molecules creating a vibration that gives off the heat energy needed. Previous studies have used microwaves for gold nanoparticle synthesis; however, polar solvents were used that partially absorbed incident microwaves, leading to partial thermal heating of the sample rather than taking full advantage of the microwave to solely heat the gold nanoparticle precursors in a non-polar solution. Through this project, microwaves were utilized as the sole heat source, and non-polar solvents were used to explore the effects of microwave heating only as pertains to the precursor material. Our findings show that the use of non-polar solvents allows for more rapid heating as compared to polar solvents, and a reduction in reaction time from 10 minutes to 1more » minute; this maximizes the efficiency of the reaction, and allows for reproducibility in the size/shape of the fabricated nanoparticles.« less

Authors:
 [1];  [1];  [1];  [1];  [1]
  1. Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)
Publication Date:
Research Org.:
Savannah River Site (SRS), Aiken, SC (United States)
Sponsoring Org.:
USDOE Office of Environmental Management (EM); USDOE Office of Science (SC), Workforce Development for Teachers and Scientists (WDTS) (SC-27)
OSTI Identifier:
1281776
Report Number(s):
SRNL-STI-2016-00424
TRN: US1601669
DOE Contract Number:
AC09-08SR22470
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
77 NANOSCIENCE AND NANOTECHNOLOGY; NANOPARTICLES; GOLD; MICROWAVE HEATING; SYNTHESIS; SOLVENTS; COMPARATIVE EVALUATIONS; PARTICLE SIZE; PRECURSOR; EFFICIENCY; SHAPE

Citation Formats

Krantz, Kelsie E., Christian, Jonathan H., Coopersmith, Kaitlin, Washington, II, Aaron L., and Murph, Simona H.. Gold Nanoparticle Microwave Synthesis. United States: N. p., 2016. Web. doi:10.2172/1281776.
Krantz, Kelsie E., Christian, Jonathan H., Coopersmith, Kaitlin, Washington, II, Aaron L., & Murph, Simona H.. Gold Nanoparticle Microwave Synthesis. United States. doi:10.2172/1281776.
Krantz, Kelsie E., Christian, Jonathan H., Coopersmith, Kaitlin, Washington, II, Aaron L., and Murph, Simona H.. Wed . "Gold Nanoparticle Microwave Synthesis". United States. doi:10.2172/1281776. https://www.osti.gov/servlets/purl/1281776.
@article{osti_1281776,
title = {Gold Nanoparticle Microwave Synthesis},
author = {Krantz, Kelsie E. and Christian, Jonathan H. and Coopersmith, Kaitlin and Washington, II, Aaron L. and Murph, Simona H.},
abstractNote = {At the nanometer scale, numerous compounds display different properties than those found in bulk material that can prove useful in areas such as medicinal chemistry. Gold nanoparticles, for example, display promise in newly developed hyperthermia therapies for cancer treatment. Currently, gold nanoparticle synthesis is performed via the hot injection technique which has large variability in final particle size and a longer reaction time. One underdeveloped area by which these particles could be produced is through microwave synthesis. To initiate heating, microwaves agitate polar molecules creating a vibration that gives off the heat energy needed. Previous studies have used microwaves for gold nanoparticle synthesis; however, polar solvents were used that partially absorbed incident microwaves, leading to partial thermal heating of the sample rather than taking full advantage of the microwave to solely heat the gold nanoparticle precursors in a non-polar solution. Through this project, microwaves were utilized as the sole heat source, and non-polar solvents were used to explore the effects of microwave heating only as pertains to the precursor material. Our findings show that the use of non-polar solvents allows for more rapid heating as compared to polar solvents, and a reduction in reaction time from 10 minutes to 1 minute; this maximizes the efficiency of the reaction, and allows for reproducibility in the size/shape of the fabricated nanoparticles.},
doi = {10.2172/1281776},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Jul 27 00:00:00 EDT 2016},
month = {Wed Jul 27 00:00:00 EDT 2016}
}

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