Apparatus comprising magnetically actuated valves and uses thereof
Abstract
The present invention, in part, relates to an apparatus having a single-use, normally-closed fluidic valve that is initially maintained in the closed position by a valve element bonded to an adhesive coating. The valve is opened using a magnetic force. The valve element includes a magnetic material or metal. In some examples, the valve is opened by bringing a magnet in proximity to the valve element to provide a magnetic force that delaminates the valve element from the adhesive coating. In particular, the apparatus can be useful for on-chip amplification and/or detection of various targets, including biological targets and any amplifiable targets. Such apparatuses and methods are useful for in-field or real-time detection of targets, especially in limited resource settings.
- Inventors:
- Publication Date:
- Research Org.:
- Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1261607
- Patent Number(s):
- 9,389,231
- Application Number:
- 14/157,335
- Assignee:
- Sandia Corporation (Albuquerque, NM)
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2014 Jan 16
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 42 ENGINEERING; 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Edwards, Thayne L., and Harper, Jason C. Apparatus comprising magnetically actuated valves and uses thereof. United States: N. p., 2016.
Web.
Edwards, Thayne L., & Harper, Jason C. Apparatus comprising magnetically actuated valves and uses thereof. United States.
Edwards, Thayne L., and Harper, Jason C. Tue .
"Apparatus comprising magnetically actuated valves and uses thereof". United States. https://www.osti.gov/servlets/purl/1261607.
@article{osti_1261607,
title = {Apparatus comprising magnetically actuated valves and uses thereof},
author = {Edwards, Thayne L. and Harper, Jason C.},
abstractNote = {The present invention, in part, relates to an apparatus having a single-use, normally-closed fluidic valve that is initially maintained in the closed position by a valve element bonded to an adhesive coating. The valve is opened using a magnetic force. The valve element includes a magnetic material or metal. In some examples, the valve is opened by bringing a magnet in proximity to the valve element to provide a magnetic force that delaminates the valve element from the adhesive coating. In particular, the apparatus can be useful for on-chip amplification and/or detection of various targets, including biological targets and any amplifiable targets. Such apparatuses and methods are useful for in-field or real-time detection of targets, especially in limited resource settings.},
doi = {},
url = {https://www.osti.gov/biblio/1261607},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {7}
}
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