Structure and Hydration of Highly-Branched, Monodisperse Phytoglycogen Nanoparticles

Nickels, Jonathan D.; Atkinson, John; Papp-Szabo, Erzsebet; Stanley, Christopher; Diallo, Souleymane O.; Perticaroli, Stefania; Baylis, Benjamin; Mahon, Perry; Ehlers, Georg; Katsaras, John; Dutcher, John R.

doi:10.1021/acs.biomac.5b01393

Title: Structure and Hydration of Highly-Branched, Monodisperse Phytoglycogen Nanoparticles

Journal Article · Sat Jan 30 00:00:00 EST 2016 · Biomacromolecules

DOI:https://doi.org/10.1021/acs.biomac.5b01393· OSTI ID:1261307

Nickels, Jonathan D. ^[1]; Atkinson, John ^[2]; Papp-Szabo, Erzsebet ^[2]; Stanley, Christopher ^[3]; Diallo, Souleymane O. ^[4]; Perticaroli, Stefania ^[2]; Baylis, Benjamin ^[2]; Mahon, Perry ^[2]; Ehlers, Georg ^[5]; Katsaras, John ^[6]; Dutcher, John R. ^[2]

Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Joint Inst. for Neutron Sciences; Univ. of Tennessee, Knoxville, TN (United States). Dept. of Physics; Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Biology and Soft Matter Division
Univ. of Guelph, ON (Canada). Dept. of Physics
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Biology and Soft Matter Division
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Chemical and Engineering Materials Division
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Quantum Condensed Matter Division
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Joint Inst. for Neutron Sciences; Univ. of Tennessee, Knoxville, TN (United States). Dept. of Physics; Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Biology and Soft Matter Division

Phytoglycogen is a naturally occurring polysaccharide nanoparticle made up of extensively branched glucose monomers. It has a number of unusual and advantageous properties, such as high water retention, low viscosity, and high stability in water, which make this biomaterial a promising candidate for a wide variety of applications. For this paper, we have characterized the structure and hydration of aqueous dispersions of phytoglycogen nanoparticles using neutron scattering. Small angle neutron scattering results suggest that the phytoglycogen nanoparticles behave similar to hard sphere colloids and are hydrated by a large number of water molecules (each nanoparticle contains between 250% and 285% of its mass in water). This suggests that phytoglycogen is an ideal sample in which to study the dynamics of hydration water. To this end, we used quasielastic neutron scattering (QENS) to provide an independent and consistent measure of the hydration number, and to estimate the retardation factor (or degree of water slow-down) for hydration water translational motions. These data demonstrate a length-scale dependence in the measured retardation factors that clarifies the origin of discrepancies between retardation factor values reported for hydration water using different experimental techniques. Finally, the present approach can be generalized to other systems containing nanoconfined water.

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Research Organization:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES); Ontario Ministry of Agriculture (OMAF) (Canada); Natural Sciences and Engineering Research Council of Canada (NSERC)

Grant/Contract Number:: AC05-00OR22725; FG02-08ER46528

OSTI ID:: 1261307

Journal Information:: Biomacromolecules, Vol. 17, Issue 3; ISSN 1525-7797

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 56 works

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