skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: The linac coherent light source single particle imaging road map

Authors:
 [1];  [2];  [3];  [3];  [3];  [3];  [4];  [5];  [6];  [7];  [8];  [9];  [10];  [11];  [3];  [12];  [3];  [13];  [14];  [6] more »;  [15];  [16];  [17];  [18];  [19];  [20];  [21];  [22];  [23];  [24] « less
  1. SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA; European XFEL GmbH, Albert-Einstein-Ring 19, Hamburg 22671, Germany
  2. Center for Free-Electron Laser Science, DESY, Notkestr. 85, 22607 Hamburg, Germany
  3. SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA
  4. SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA; Department of Materials Science and Engineering, Stanford University, Stanford, California 94305, USA; Department of Physics, Stanford University, Stanford, California 94305, USA
  5. SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA; Department of Physics, Stanford University, Stanford, California 94305, USA
  6. Lawrence Berkeley National Laboratory, 1 Cyclotron Rd., Berkeley, California 94720, USA
  7. Shanghai Institute of Applied Physics, Chinese Academy of Sciences, 239 Zhangheng Road, Shanghai 201204, China; ShanghaiTech University, 99 Haike Road, Shanghai 201210, China
  8. Department of Biochemistry Molecular Biology, Monash University, Clayton 3800, Australia; ARC Centre of Excellence for Advanced Molecular Imaging, Clayton 3800, Australia
  9. SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA; Department of Physics, Cornell University, Ithaca, New York 14853, USA
  10. PULSE Institute, SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA
  11. Laboratory of Molecular Biophysics, Department of Cell and Molecular Biology, Uppsala University, Husargatan 3, 75124 Uppsala, Sweden; European XFEL GmbH, Albert-Einstein-Ring 19, Hamburg 22671, Germany
  12. Lawrence Livermore National Laboratory, Livermore, California 94550, USA
  13. BioXFEL Center and Department of Structural Biology, University at Buffalo, SUNY, 700 Ellicott Street, Buffalo, New York 14203, USA; Hauptman-Woodward Institute, 700 Ellicott Street, Buffalo, New York 14203, USA
  14. Laboratory of Molecular Biophysics, Department of Cell and Molecular Biology, Uppsala University, Husargatan 3, 75124 Uppsala, Sweden; Lawrence Berkeley National Laboratory, 1 Cyclotron Rd., Berkeley, California 94720, USA
  15. Department of Physics, University of Wisconsin Milwaukee, 1900 E. Kenwood Blvd, Milwaukee, Wisconsin 53211, USA
  16. SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA; UCLA Department of Physics and Astronomy, 475 Portola Plaza, Los Angeles, California 90095, USA
  17. Center for Free-Electron Laser Science, DESY, Notkestr. 85, 22607 Hamburg, Germany; Department of Physics, University of Hamburg, Jungiusstr. 9, 20355 Hamburg, Germany
  18. Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany
  19. Deutsches Elektronen-Synchrotron DESY, Notkestraße 85, 22607 Hamburg, Germany
  20. Department of Physics, Arizona State University, Rural Rd, Tempe, Arizona 85287, USA
  21. Deutsches Elektronen-Synchrotron DESY, Notkestraße 85, 22607 Hamburg, Germany; National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Kashirskoe shosse 31, 115409 Moscow, Russia
  22. SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA; School of Medicine, Stanford University, 299 Campus Drive, Stanford, California 94305, USA
  23. School of Medicine, Stanford University, 299 Campus Drive, Stanford, California 94305, USA
  24. SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, USA; Brookhaven National Laboratory, P.O. BOX 5000, Upton, New York 11973, USA
Publication Date:
Research Org.:
SLAC National Accelerator Lab., Menlo Park, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1261129
DOE Contract Number:  
STC 1231306; AC02-76SF00515; FG02-09ER16114; AC52-07NA27344; 05K2012
Resource Type:
Journal Article
Journal Name:
Structural Dynamics
Additional Journal Information:
Journal Volume: 2; Journal Issue: 4; Journal ID: ISSN 2329-7778
Country of Publication:
United States
Language:
English

Citation Formats

Aquila, A., Barty, A., Bostedt, C., Boutet, S., Carini, G., dePonte, D., Drell, P., Doniach, S., Downing, K. H., Earnest, T., Elmlund, H., Elser, V., Gühr, M., Hajdu, J., Hastings, J., Hau-Riege, S. P., Huang, Z., Lattman, E. E., Maia, F. R. N. C., Marchesini, S., Ourmazd, A., Pellegrini, C., Santra, R., Schlichting, I., Schroer, C., Spence, J. C. H., Vartanyants, I. A., Wakatsuki, S., Weis, W. I., and Williams, G. J. The linac coherent light source single particle imaging road map. United States: N. p., 2015. Web. doi:10.1063/1.4918726.
Aquila, A., Barty, A., Bostedt, C., Boutet, S., Carini, G., dePonte, D., Drell, P., Doniach, S., Downing, K. H., Earnest, T., Elmlund, H., Elser, V., Gühr, M., Hajdu, J., Hastings, J., Hau-Riege, S. P., Huang, Z., Lattman, E. E., Maia, F. R. N. C., Marchesini, S., Ourmazd, A., Pellegrini, C., Santra, R., Schlichting, I., Schroer, C., Spence, J. C. H., Vartanyants, I. A., Wakatsuki, S., Weis, W. I., & Williams, G. J. The linac coherent light source single particle imaging road map. United States. doi:10.1063/1.4918726.
Aquila, A., Barty, A., Bostedt, C., Boutet, S., Carini, G., dePonte, D., Drell, P., Doniach, S., Downing, K. H., Earnest, T., Elmlund, H., Elser, V., Gühr, M., Hajdu, J., Hastings, J., Hau-Riege, S. P., Huang, Z., Lattman, E. E., Maia, F. R. N. C., Marchesini, S., Ourmazd, A., Pellegrini, C., Santra, R., Schlichting, I., Schroer, C., Spence, J. C. H., Vartanyants, I. A., Wakatsuki, S., Weis, W. I., and Williams, G. J. Wed . "The linac coherent light source single particle imaging road map". United States. doi:10.1063/1.4918726.
@article{osti_1261129,
title = {The linac coherent light source single particle imaging road map},
author = {Aquila, A. and Barty, A. and Bostedt, C. and Boutet, S. and Carini, G. and dePonte, D. and Drell, P. and Doniach, S. and Downing, K. H. and Earnest, T. and Elmlund, H. and Elser, V. and Gühr, M. and Hajdu, J. and Hastings, J. and Hau-Riege, S. P. and Huang, Z. and Lattman, E. E. and Maia, F. R. N. C. and Marchesini, S. and Ourmazd, A. and Pellegrini, C. and Santra, R. and Schlichting, I. and Schroer, C. and Spence, J. C. H. and Vartanyants, I. A. and Wakatsuki, S. and Weis, W. I. and Williams, G. J.},
abstractNote = {},
doi = {10.1063/1.4918726},
journal = {Structural Dynamics},
issn = {2329-7778},
number = 4,
volume = 2,
place = {United States},
year = {2015},
month = {7}
}

Works referenced in this record:

Potential for biomolecular imaging with femtosecond X-ray pulses
journal, August 2000

  • Neutze, Richard; Wouts, Remco; van der Spoel, David
  • Nature, Vol. 406, Issue 6797
  • DOI: 10.1038/35021099

Single mimivirus particles intercepted and imaged with an X-ray laser
journal, February 2011

  • Seibert, M. Marvin; Ekeberg, Tomas; Maia, Filipe R. N. C.
  • Nature, Vol. 470, Issue 7332
  • DOI: 10.1038/nature09748

Femtosecond free-electron laser x-ray diffraction data sets for algorithm development
journal, January 2012

  • Kassemeyer, Stephan; Steinbrener, Jan; Lomb, Lukas
  • Optics Express, Vol. 20, Issue 4
  • DOI: 10.1364/OE.20.004149

High-throughput imaging of heterogeneous cell organelles with an X-ray laser
journal, November 2014


Imaging single cells in a beam of live cyanobacteria with an X-ray laser
journal, February 2015

  • van der Schot, Gijs; Svenda, Martin; Maia, Filipe R. N. C.
  • Nature Communications, Vol. 6, Issue 1
  • DOI: 10.1038/ncomms6704

Three-Dimensional Reconstruction of the Giant Mimivirus Particle with an X-Ray Free-Electron Laser
journal, March 2015


Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight
journal, June 2012

  • Loh, N. D.; Hampton, C. Y.; Martin, A. V.
  • Nature, Vol. 486, Issue 7404
  • DOI: 10.1038/nature11222

Femtosecond dark-field imaging with an X-ray free electron laser
journal, January 2012

  • Martin, A. V.; Loh, N. D.; Hampton, C. Y.
  • Optics Express, Vol. 20, Issue 12
  • DOI: 10.1364/OE.20.013501

Shapes and vorticities of superfluid helium nanodroplets
journal, August 2014


Impact of hollow-atom formation on coherent x-ray scattering at high intensity
journal, March 2011


Femtosecond electronic response of atoms to ultra-intense X-rays
journal, July 2010


Impact of ultrafast electronic damage in single-particle x-ray imaging experiments
journal, November 2012


Photoelectron Dynamics in X-Ray Free-Electron-Laser Diffractive Imaging of Biological Samples
journal, June 2012


Size-Dependent Ultrafast Ionization Dynamics of Nanoscale Samples in Intense Femtosecond X-Ray Free-Electron-Laser Pulses
journal, June 2012


X-ray atomic scattering factors of low- Z ions with a core hole
journal, October 2007


Incoherent x-ray scattering in single molecule imaging
journal, July 2014


Encapsulation and Diffraction-Pattern-Correction Methods to Reduce the Effect of Damage in X-Ray Diffraction Imaging of Single Biological Molecules
journal, May 2007


Structural variability and the incoherent addition of scattered intensities in single-particle diffraction
journal, September 2009


X-Ray Diffraction from Isolated and Strongly Aligned Gas-Phase Molecules with a Free-Electron Laser
journal, February 2014


Coherent lensless X-ray imaging
journal, November 2010


Invited Article: A unified evaluation of iterative projection algorithms for phase retrieval
journal, January 2007

  • Marchesini, S.
  • Review of Scientific Instruments, Vol. 78, Issue 1
  • DOI: 10.1063/1.2403783

Structure from fleeting illumination of faint spinning objects in flight
journal, November 2008

  • Fung, Russell; Shneerson, Valentin; Saldin, Dilano K.
  • Nature Physics, Vol. 5, Issue 1
  • DOI: 10.1038/nphys1129

Reconstruction algorithm for single-particle diffraction imaging experiments
journal, August 2009


Toward unsupervised single-shot diffractive imaging of heterogeneous particles using X-ray free-electron lasers
journal, January 2013

  • Park, Hyung Joo; Loh, N. Duane; Sierra, Raymond G.
  • Optics Express, Vol. 21, Issue 23
  • DOI: 10.1364/OE.21.028729

    Works referencing / citing this record:

    Theoretical evidence for the sensitivity of charge-rearrangement-enhanced x-ray ionization to molecular size
    journal, July 2019


    Reproducibility of single protein explosions induced by X-ray lasers
    journal, January 2018

    • Östlin, Christofer; Tîmneanu, Nicusor; Jönsson, H. Olof
    • Physical Chemistry Chemical Physics, Vol. 20, Issue 18
    • DOI: 10.1039/c7cp07267h

    Wavefront sensing at X-ray free-electron lasers
    journal, June 2019

    • Seaberg, Matthew; Cojocaru, Ruxandra; Berujon, Sebastien
    • Journal of Synchrotron Radiation, Vol. 26, Issue 4
    • DOI: 10.1107/s1600577519005721

    Diffraction data of core-shell nanoparticles from an X-ray free electron laser
    journal, April 2017

    • Li, Xuanxuan; Chiu, Chun-Ya; Wang, Hsiang-Ju
    • Scientific Data, Vol. 4, Issue 1
    • DOI: 10.1038/sdata.2017.48

    Software Platform for European XFEL: Towards Online Experimental Data Analysis
    journal, November 2018

    • Bobkov, S. A.; Teslyuk, A. B.; Zolotarev, S. I.
    • Lobachevskii Journal of Mathematics, Vol. 39, Issue 9
    • DOI: 10.1134/s1995080218090093

    A comprehensive simulation framework for imaging single particles and biomolecules at the European X-ray Free-Electron Laser
    journal, April 2016

    • Yoon, Chun Hong; Yurkov, Mikhail V.; Schneidmiller, Evgeny A.
    • Scientific Reports, Vol. 6, Issue 1
    • DOI: 10.1038/srep24791

    Reversible rearrangement of magnetic nanoparticles in solution studied using time-resolved SAXS method
    journal, June 2019


    The Single Particles, Clusters and Biomolecules and Serial Femtosecond Crystallography instrument of the European XFEL: initial installation
    journal, April 2019

    • Mancuso, Adrian P.; Aquila, Andrew; Batchelor, Lewis
    • Journal of Synchrotron Radiation, Vol. 26, Issue 3
    • DOI: 10.1107/s1600577519003308

    Calculation of x-ray scattering patterns from nanocrystals at high x-ray intensity
    journal, July 2016

    • Abdullah, Malik Muhammad; Jurek, Zoltan; Son, Sang-Kil
    • Structural Dynamics, Vol. 3, Issue 5
    • DOI: 10.1063/1.4958887