Locking Two Rigid-body Bundles in an Outward-Facing Conformation: The Ion-coupling Mechanism in a LeuT-fold Transporter
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journal
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December 2019 |
Conformational transitions of the sodium-dependent sugar transporter, vSGLT
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journal
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March 2018 |
A Perspective: Active Role of Lipids in Neurotransmitter Dynamics
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journal
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October 2019 |
Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics
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journal
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October 2019 |
Expression and purification of a functional heteromeric GABAA receptor for structural studies
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journal
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July 2018 |
The Use of Multiscale Molecular Simulations in Understanding a Relationship between the Structure and Function of Biological Systems of the Brain: The Application to Monoamine Oxidase Enzymes
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journal
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July 2016 |
A structural model of the human serotonin transporter in an outward-occluded state
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journal
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June 2019 |
Unravelling the Weak Interactions in Binary Clusters of Serotonin and Amino Acid Residues
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journal
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September 2019 |
Dimer Interface of the Human Serotonin Transporter and Effect of the Membrane Composition
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journal
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March 2018 |
Molecular Modelling of Potential Candidates for the Treatment of Depression
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April 2019 |
Structural biology of solute carrier (SLC) membrane transport proteins
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February 2017 |
Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis
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journal
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May 2018 |
Synthesis of Novel Nicotinic Ligands with Multimodal Action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters
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journal
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October 2019 |
Identification and characterization of the Fasciola hepatica sodium- and chloride-dependent taurine transporter
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April 2018 |
Amino Acid Transporters as Disease Modifiers and Drug Targets
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March 2018 |
Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport
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April 2019 |
α-Fluorination of carbonyls with nucleophilic fluorine
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journal
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March 2019 |
Resculpting the binding pocket of APC superfamily LeuT-fold amino acid transporters
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journal
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October 2017 |
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
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journal
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March 2020 |
Modification of a Putative Third Sodium Site in the Glycine Transporter GlyT2 Influences the Chloride Dependence of Substrate Transport
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journal
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September 2018 |
A Dynamic Interaction of Coomassie Dye with the Glycine Transporters N-termini
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journal
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October 2016 |
Targeting Neuroblastoma Cell Surface Proteins: Recommendations for Homology Modeling of hNET, ALK, and TrkB
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journal
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January 2017 |
X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release
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journal
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February 2020 |
Thermostabilization and purification of the human dopamine transporter (hDAT) in an inhibitor and allosteric ligand bound conformation
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journal
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May 2018 |
Computational identification of the binding mechanism of a triple reuptake inhibitor amitifadine for the treatment of major depressive disorder
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journal
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January 2018 |
Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter
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journal
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September 2016 |
From linked open data to molecular interaction: studying selectivity trends for ligands of the human serotonin and dopamine transporter
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journal
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January 2016 |
The role of interfacial lipids in stabilizing membrane protein oligomers
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journal
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January 2017 |
The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor
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journal
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July 2019 |
Cholesterol binding to a conserved site modulates the conformation, pharmacology, and transport kinetics of the human serotonin transporter
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journal
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January 2018 |
Norepinephrine transporter-derived homing peptides enable rapid endocytosis of drug delivery nanovehicles into neuroblastoma cells
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journal
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July 2020 |
Electrogenic Binding of Intracellular Cations Defines a Kinetic Decision Point in the Transport Cycle of the Human Serotonin Transporter
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journal
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December 2016 |
Structures of human ENT1 in complex with adenosine reuptake inhibitors
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journal
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June 2019 |
Current and Future Challenges in GPCR Drug Discovery
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book
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November 2017 |
Structure Modeling of the Norepinephrine Transporter
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journal
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January 2020 |
Molecular Modeling of Drug-Transporter Interactions-An International Transporter Consortium Perspective
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journal
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August 2018 |
Comparison of computational model and X-ray crystal structure of human serotonin transporter: potential application for the pharmacology of human monoamine transporters
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journal
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May 2017 |
Analysis and measurement of serotonin
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journal
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November 2017 |
Immunomodulatory Action of Substituted 1,3,4-Thiadiazines on the Course of Myocardial Infarction
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journal
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July 2018 |
Structure and Gating Dynamics of Na+/Cl– Coupled Neurotransmitter Transporters
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journal
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September 2019 |
A direct interaction of cholesterol with the dopamine transporter prevents its out-to-inward transition
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journal
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January 2018 |
A label-free approach to detect ligand binding to cell surface proteins in real time
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journal
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April 2018 |
Role of Microbiota and Tryptophan Metabolites in the Remote Effect of Intestinal Inflammation on Brain and Depression
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journal
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June 2018 |
Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation
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journal
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March 2019 |
Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family
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journal
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January 2017 |
A partially-open inward-facing intermediate conformation of LeuT is associated with Na+ release and substrate transport
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journal
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January 2018 |
3D similarities between the binding sites of monoaminergic target proteins
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journal
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July 2018 |
Unveiling Pharmacological Responses and Potential Targets Insights of Identified Bioactive Constituents of Cuscuta reflexa Roxb. Leaves through In Vivo and In Silico Approaches
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journal
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March 2020 |
Modeling and Dynamics of the Inward-Facing State of a Na+/Cl− Dependent Neurotransmitter Transporter Homologue
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journal
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August 2010 |
Tales of tails in transporters
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journal
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June 2019 |
Intestinal serotonin and fluoxetine exposure modulate bacterial colonization in the gut
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journal
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September 2019 |
The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter
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journal
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March 2020 |
Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT
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journal
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May 2018 |
Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain
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journal
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June 2018 |
A Markov State-based Quantitative Kinetic Model of Sodium Release from the Dopamine Transporter
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journal
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January 2017 |
Thermostabilization and purification of the human dopamine transporter (hDAT) in an inhibitor and allosteric ligand bound conformation
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journal
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July 2018 |
Identification of novel inhibitors of the amino acid transporter B 0 AT1 (SLC6A19), a potential target to induce protein restriction and to treat type 2 diabetes: Novel SLC6A19 inhibitors
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journal
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February 2017 |
Mechanistic Insights into the Stimulant Properties of Novel Psychoactive Substances (NPS) and Their Discrimination by the Dopamine Transporter—In Silico and In Vitro Exploration of Dissociative Diarylethylamines
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journal
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April 2018 |
Trimerization of dopamine transporter triggered by AIM-100 binding: Molecular mechanism and effect of mutations
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journal
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December 2019 |
Functional Reconstitution of Membrane Proteins Derived From Eukaryotic Cell-Free Systems
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journal
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August 2019 |
Consensus designs and thermal stability determinants of a human glutamate transporter
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journal
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October 2018 |
Modulation of LAT1 (SLC7A5) transporter activity and stability by membrane cholesterol
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journal
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March 2017 |
Heterogeneities in Axonal Structure and Transporter Distribution Lower Dopamine Reuptake Efficiency
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journal
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January 2018 |
Targeting of dopamine transporter to filopodia requires an outward-facing conformation of the transporter
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journal
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July 2017 |
Structural basis for recognition of diverse antidepressants by the human serotonin transporter
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journal
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January 2018 |
Serotonin transport in the 21st century
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journal
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September 2019 |
Mapping Cholesterol Interaction Sites on Serotonin Transporter through Coarse-Grained Molecular Dynamics
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journal
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December 2016 |
Genome-Wide Identification, Characterization and Expression Analysis of the Solute Carrier 6 Gene Family in Silkworm (Bombyx mori)
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journal
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October 2016 |
Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site
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journal
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May 2018 |
Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters
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journal
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November 2018 |
Neurobiology of Anorexia Nervosa: Serotonin Dysfunctions Link Self-Starvation with Body Image Disturbances through an Impaired Body Memory
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journal
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November 2016 |
Transporter oligomerisation: roles in structure and function
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journal
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December 2018 |
A current view of serotonin transporters
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journal
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July 2016 |
Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation
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journal
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February 2017 |
Impact of disruption of secondary binding site S2on dopamine transporter function
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journal
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July 2016 |
RCSB Protein Data Bank: Enabling biomedical research and drug discovery
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journal
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November 2019 |
On the Role of a Conserved Methionine in the Na+-Coupling Mechanism of a Neurotransmitter Transporter Homolog
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journal
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February 2021 |
OCTN: A Small Transporter Subfamily with Great Relevance to Human Pathophysiology, Drug Discovery, and Diagnostics
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journal
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December 2018 |
Function and Regulation of Acid Resistance Antiporters
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journal
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June 2019 |
Revealing vilazodone's binding mechanism underlying its partial agonism to the 5-HT 1A receptor in the treatment of major depressive disorder
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journal
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January 2017 |
Characterization of transgenic mouse lines for labeling type I and type II afferent neurons in the cochlea
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journal
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April 2019 |
Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT
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journal
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September 2018 |
Monoamine transporters: structure, intrinsic dynamics and allosteric regulation
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journal
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July 2019 |
Human dopamine transporter: the first implementation of a combined in silico/in vitro approach revealing the substrate and inhibitor specificities
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journal
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January 2018 |
Human dopamine transporter: the first implementation of a combined in silico/in vitro approach revealing the substrate and inhibitor specificities
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text
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January 2018 |
Competition between Li + and Na + in sodium transporters and receptors: Which Na + -Binding sites are “therapeutic” Li + targets?
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journal
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January 2018 |
Conformational dynamics of the human serotonin transporter during substrate and drug binding
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journal
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April 2019 |
Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family
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text
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January 2017 |
Shared dynamics of LeuT superfamily members and allosteric differentiation by structural irregularities and multimerization
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journal
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May 2018 |
Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM
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journal
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April 2019 |
Substrate-induced conformational dynamics of the dopamine transporter
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journal
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June 2019 |
Computational characterization of the selective inhibition of human norepinephrine and serotonin transporters by an escitalopram scaffold
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journal
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January 2018 |
Overview of Monoamine Transporters
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journal
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December 2017 |