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Title: Biological production of organic compounds

Abstract

Strains of cyanobacteria that produce high levels of alpha ketoglutarate (AKG) and pyruvate are disclosed herein. Methods of culturing these cyanobacteria to produce AKG or pyruvate and recover AKG or pyruvate from the culture are also described herein. Nucleic acid sequences encoding polypeptides that function as ethylene-forming enzymes and their use in the production of ethylene are further disclosed herein. These nucleic acids may be expressed in hosts such as cyanobacteria, which in turn may be cultured to produce ethylene.

Inventors:
; ; ; ;
Publication Date:
Research Org.:
National Renewable Energy Lab. (NREL), Golden, CO (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1246901
Patent Number(s):
9,309,541
Application Number:
14/643,788
Assignee:
Alliance for Sustainable Energy, LLC (Golden, CO) NREL
DOE Contract Number:  
AC36-08GO28308
Resource Type:
Patent
Resource Relation:
Patent File Date: 2015 Mar 10
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Yu, Jianping, Paddock, Troy, Carrieri, Damian, Maness, Pin-Ching, and Seibert, Michael. Biological production of organic compounds. United States: N. p., 2016. Web.
Yu, Jianping, Paddock, Troy, Carrieri, Damian, Maness, Pin-Ching, & Seibert, Michael. Biological production of organic compounds. United States.
Yu, Jianping, Paddock, Troy, Carrieri, Damian, Maness, Pin-Ching, and Seibert, Michael. Tue . "Biological production of organic compounds". United States. doi:. https://www.osti.gov/servlets/purl/1246901.
@article{osti_1246901,
title = {Biological production of organic compounds},
author = {Yu, Jianping and Paddock, Troy and Carrieri, Damian and Maness, Pin-Ching and Seibert, Michael},
abstractNote = {Strains of cyanobacteria that produce high levels of alpha ketoglutarate (AKG) and pyruvate are disclosed herein. Methods of culturing these cyanobacteria to produce AKG or pyruvate and recover AKG or pyruvate from the culture are also described herein. Nucleic acid sequences encoding polypeptides that function as ethylene-forming enzymes and their use in the production of ethylene are further disclosed herein. These nucleic acids may be expressed in hosts such as cyanobacteria, which in turn may be cultured to produce ethylene.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 12 00:00:00 EDT 2016},
month = {Tue Apr 12 00:00:00 EDT 2016}
}

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Works referenced in this record:

Sucrose accumulation in salt-stressed cells of agp gene deletion-mutant in cyanobacterium Synechocystis sp. PCC 6803
journal, January 2003


Photosynthetic conversion of carbon dioxide to ethylene by the recombinant cyanobacterium, Synechococcus sp. PCC 7942, which harbors a gene for the ethylene-forming enzyme of Pseudomonas syringae
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Construction and analysis of a recombinant cyanobacterium expressing a chromosomally inserted gene for an ethylene-forming enzyme at the psbAI locus
journal, January 2003

  • Takahama, Kazutaka; Matsuoka, Masayoshi; Nagahama, Kazuhiro
  • Journal of Bioscience and Bioengineering, Vol. 95, Issue 3, p. 302-305
  • DOI: 10.1016/S1389-1723(03)80034-8

Modification of carbon partitioning to enhance PHB production in Synechocystis sp. PCC6803
journal, May 2002