Proposed biokinetic model for phosphorus
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
This paper reviews data related to the biokinetics of phosphorus in the human body and proposes a biokinetic model for systemic phosphorus for use in updated International Commission on Radiological Protection (ICRP) guidance on occupational intake of radionuclides. Compared with the ICRP s current occupational model for phosphorus (Publication 68, 1994) the proposed model provides a more realistic description of the paths of movement of phosphorus in the body and improved consistency with experimental, medical, and environmental data on the time-dependent distribution and retention of phosphorus following uptake to blood. For acute uptake of 32P to blood, the proposed model yields roughly a 50% decrease in dose estimates for bone surface and red marrow and a 6-fold increase in estimates for liver and kidney compared with the biokinetic model of Publication 68 (applying Publication 68 dosimetric models in both sets of calculations). For acute uptake of 33P to blood, the proposed model yields roughly a 50% increase in dose estimates for bone surface and red marrow and a 7-fold increase in estimates for liver and kidney compared with the model of Publication 68.
- Research Organization:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-00OR22725
- OSTI ID:
- 1240514
- Journal Information:
- Journal of Radiological Protection, Vol. 34, Issue 2; ISSN 0952-4746
- Publisher:
- IOP Publishing
- Country of Publication:
- United States
- Language:
- English
Similar Records
An age- and sex-specific biokinetic model for radon*
Dosimetry is Key to Good Epidemiology: Workers at Mallinckrodt Chemical Works had Seven Different Source Exposures