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Title: Acid–Base Bifunctional Shell Cross-Linked Micelle Nanoreactor for One-Pot Tandem Reaction

Journal Article · · ACS Catalysis
 [1];  [2];  [2];  [1]
  1. School of Chemical &, Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332-0100, United States
  2. Molecular Design Institute and Department of Chemistry, New York University, New York, New York 10003-6688, United States
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Shell cross-linked micelles (SCMs) containing acidic sites in the shell and basic sites in the core are prepared from amphiphilic poly(2-oxazoline) triblock copolymers. The materials are utilized as two chamber nanoreactors for a prototypical acid-base bifunctional tandem deacetalization-nitroaldol reaction. The acid and base sites are localized in different regions of the micelle, allowing the two steps in the reaction sequence to largely proceed in separate compartments, akin to the compartmentalization that occurs in biological systems.

Research Organization:
Georgia Institute of Technology, Atlanta, GA (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES)
Grant/Contract Number:
FG02-03ER15459
OSTI ID:
1234184
Alternate ID(s):
OSTI ID: 1240019; OSTI ID: 1657459
Journal Information:
ACS Catalysis, Journal Name: ACS Catalysis Vol. 6 Journal Issue: 2; ISSN 2155-5435
Publisher:
American Chemical Society (ACS)Copyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 87 works
Citation information provided by
Web of Science

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Acids and Bases in One Pot while Avoiding Their Mutual Destruction We gratefully acknowledge support from the Israel Science Foundation (grant 96-98-2) and from the Infrastructure (Tashtiot) Project of the Israel Ministry for Science, Arts and Sports; and from the German–Israeli Foundation for Scientific Research and Development (Grant No. I-530.045.05/97). journal October 2001
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Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
36 MATERIALS SCIENCE
Site-isolation
cross-linked micelle
deacetalization
nitroaldol
acid−base tandem reaction
nanoreactor
catalysts
acid and base chemistry
Micelles
polymers
copolymers