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Title: Succinic acid production on xylose-enriched biorefinery streams by Actinobacillus succinogenes in batch fermentation

Abstract

Co-production of chemicals from lignocellulosic biomass alongside fuels holds promise for improving the economic outlook of integrated biorefineries. In current biochemical conversion processes that use thermochemical pretreatment and enzymatic hydrolysis, fractionation of hemicellulose-derived and cellulose-derived sugar streams is possible using hydrothermal or dilute acid pretreatment (DAP), which then offers a route to parallel trains for fuel and chemical production from xylose- and glucose-enriched streams. Succinic acid (SA) is a co-product of particular interest in biorefineries because it could potentially displace petroleum-derived chemicals and polymer precursors for myriad applications. Furthermore, SA production from biomass-derived hydrolysates has not yet been fully explored or developed.

Authors:
 [1];  [1];  [1];  [2];  [2];  [1];  [1];  [1];  [1]
  1. National Renewable Energy Lab. (NREL), Golden, CO (United States)
  2. Univ. of Pretoria, Pretoria (South Africa)
Publication Date:
Research Org.:
National Renewable Energy Lab. (NREL), Golden, CO (United States)
Sponsoring Org.:
USDOE Office of Energy Efficiency and Renewable Energy (EERE), Bioenergy Technologies Office (EE-3B)
OSTI Identifier:
1239049
Report Number(s):
NREL/JA-5100-65902
Journal ID: ISSN 1754-6834
Grant/Contract Number:  
AC36-08GO28308
Resource Type:
Journal Article: Accepted Manuscript
Journal Name:
Biotechnology for Biofuels
Additional Journal Information:
Journal Volume: 9; Journal Issue: 1; Related Information: Biotechnology for Biofuels; Journal ID: ISSN 1754-6834
Publisher:
BioMed Central
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANAYLYTICAL CHEMISTRY; succinic acid; fermentation; biochemicals; biofuels; pretreatment; biorefinery; Actinobacillus succinogenes

Citation Formats

Salvachua, Davinia, Mohagheghi, Ali, Smith, Holly, Bradfield, Michael F. A., Nicol, Willie, Black, Brenna A., Biddy, Mary J., Dowe, Nancy, and Beckham, Gregg T. Succinic acid production on xylose-enriched biorefinery streams by Actinobacillus succinogenes in batch fermentation. United States: N. p., 2016. Web. doi:10.1186/s13068-016-0425-1.
Salvachua, Davinia, Mohagheghi, Ali, Smith, Holly, Bradfield, Michael F. A., Nicol, Willie, Black, Brenna A., Biddy, Mary J., Dowe, Nancy, & Beckham, Gregg T. Succinic acid production on xylose-enriched biorefinery streams by Actinobacillus succinogenes in batch fermentation. United States. doi:10.1186/s13068-016-0425-1.
Salvachua, Davinia, Mohagheghi, Ali, Smith, Holly, Bradfield, Michael F. A., Nicol, Willie, Black, Brenna A., Biddy, Mary J., Dowe, Nancy, and Beckham, Gregg T. Tue . "Succinic acid production on xylose-enriched biorefinery streams by Actinobacillus succinogenes in batch fermentation". United States. doi:10.1186/s13068-016-0425-1. https://www.osti.gov/servlets/purl/1239049.
@article{osti_1239049,
title = {Succinic acid production on xylose-enriched biorefinery streams by Actinobacillus succinogenes in batch fermentation},
author = {Salvachua, Davinia and Mohagheghi, Ali and Smith, Holly and Bradfield, Michael F. A. and Nicol, Willie and Black, Brenna A. and Biddy, Mary J. and Dowe, Nancy and Beckham, Gregg T.},
abstractNote = {Co-production of chemicals from lignocellulosic biomass alongside fuels holds promise for improving the economic outlook of integrated biorefineries. In current biochemical conversion processes that use thermochemical pretreatment and enzymatic hydrolysis, fractionation of hemicellulose-derived and cellulose-derived sugar streams is possible using hydrothermal or dilute acid pretreatment (DAP), which then offers a route to parallel trains for fuel and chemical production from xylose- and glucose-enriched streams. Succinic acid (SA) is a co-product of particular interest in biorefineries because it could potentially displace petroleum-derived chemicals and polymer precursors for myriad applications. Furthermore, SA production from biomass-derived hydrolysates has not yet been fully explored or developed.},
doi = {10.1186/s13068-016-0425-1},
journal = {Biotechnology for Biofuels},
number = 1,
volume = 9,
place = {United States},
year = {Tue Feb 02 00:00:00 EST 2016},
month = {Tue Feb 02 00:00:00 EST 2016}
}

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Cited by: 25 works
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Works referenced in this record:

Dilute-Sulfuric Acid Pretreatment of Corn Stover in Pilot-Scale Reactor: Investigation of Yields, Kinetics, and Enzymatic Digestibilities of Solids
journal, January 2003

  • Schell, Daniel J.; Farmer, Jody; Newman, Millie
  • Applied Biochemistry and Biotechnology, Vol. 105, Issue 1-3, p. 69-86
  • DOI: 10.1385/ABAB:105:1-3:69

Alkaline Pretreatment of Corn Stover: Bench-Scale Fractionation and Stream Characterization
journal, May 2014

  • Karp, Eric M.; Donohoe, Bryon S.; O’Brien, Marykate H.
  • ACS Sustainable Chemistry & Engineering, Vol. 2, Issue 6, p. 1481-1491
  • DOI: 10.1021/sc500126u

Lignin valorization through integrated biological funneling and chemical catalysis
journal, August 2014

  • Linger, J. G.; Vardon, D. R.; Guarnieri, M. T.
  • Proceedings of the National Academy of Sciences, Vol. 111, Issue 33, p. 12013-12018
  • DOI: 10.1073/pnas.1410657111

Fermentation of lignocellulosic hydrolysates. I: inhibition and detoxification
journal, August 2000


Deconstruction of Lignocellulosic Biomass to Fuels and Chemicals
journal, July 2011


Succinic Acid: A New Platform Chemical for Biobased Polymers from Renewable Resources
journal, May 2008

  • Bechthold, I.; Bretz, K.; Kabasci, S.
  • Chemical Engineering & Technology, Vol. 31, Issue 5, p. 647-654
  • DOI: 10.1002/ceat.200800063

Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of Escherichia coli C that produce succinate and malate
journal, January 2008

  • Jantama, Kaemwich; Haupt, M. J.; Svoronos, Spyros A.
  • Biotechnology and Bioengineering, Vol. 99, Issue 5, p. 1140-1153
  • DOI: 10.1002/bit.21694

Lignin Valorization: Improving Lignin Processing in the Biorefinery
journal, May 2014

  • Ragauskas, A. J.; Beckham, G. T.; Biddy, M. J.
  • Science, Vol. 344, Issue 6185, p. 1246843-1246843
  • DOI: 10.1126/science.1246843

Chemical Routes for the Transformation of Biomass into Chemicals
journal, June 2007

  • Corma, Avelino; Iborra, Sara; Velty, Alexandra
  • Chemical Reviews, Vol. 107, Issue 6, p. 2411-2502
  • DOI: 10.1021/cr050989d

Features of promising technologies for pretreatment of lignocellulosic biomass
journal, April 2005