Crystal Structures of AKR1C3 Containing an N-(aryl)amino-benzoate Inhibitor and a Bifunctional AKR1C3 Inhibitor and Androgen Receptor Antagonist. Therapeutic Leads for Castrate Resistant Prostate Cancer
Journal Article
·
· BioOrganic and Medicinal Chemistry Letters
- Research Organization:
- Brookhaven National Lab. (BNL), Upton, NY (United States)
- Sponsoring Organization:
- USDOE Office of Science (SC), Basic Energy Sciences (BES)
- DOE Contract Number:
- SC00112704
- OSTI ID:
- 1228994
- Report Number(s):
- BNL-111069-2015-JA
- Journal Information:
- BioOrganic and Medicinal Chemistry Letters, Vol. 22, Issue 10; ISSN 0960-894X
- Country of Publication:
- United States
- Language:
- English
Similar Records
Bone stroma-derived cells change coregulators recruitment to androgen receptor and decrease cell proliferation in androgen-sensitive and castration-resistant prostate cancer cells
Development of Potent and Selective Indomethacin Analogues for the Inhibition of AKR1C3 (Type 5 17 beta-Hydroxysteroid Dehydrogenase/Prostaglandin F Synthase) in Castrate-Resistant Prostate Cancer
Development of Potent and Selective Indomethacin Analogues for the Inhibition of AKR1C3 (Type 5 17β-Hydroxysteroid Dehydrogenase/Prostaglandin F Synthase) in Castrate-Resistant Prostate Cancer
Journal Article
·
Fri Nov 27 00:00:00 EST 2015
· Biochemical and Biophysical Research Communications
·
OSTI ID:1228994
+11 more
Development of Potent and Selective Indomethacin Analogues for the Inhibition of AKR1C3 (Type 5 17 beta-Hydroxysteroid Dehydrogenase/Prostaglandin F Synthase) in Castrate-Resistant Prostate Cancer
Journal Article
·
Thu Mar 28 00:00:00 EDT 2013
· Journal of Medicinal Chemistry
·
OSTI ID:1228994
+5 more
Development of Potent and Selective Indomethacin Analogues for the Inhibition of AKR1C3 (Type 5 17β-Hydroxysteroid Dehydrogenase/Prostaglandin F Synthase) in Castrate-Resistant Prostate Cancer
Journal Article
·
Wed Mar 13 00:00:00 EDT 2013
· Journal of Medicinal Chemistry
·
OSTI ID:1228994
+5 more