skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Celluloytic enzymes, nucleic acids encoding them and methods for making and using them

Patent ·
OSTI ID:1224888

The invention is directed to polypeptides having any cellulolytic activity, e.g., a cellulase activity, e.g., endoglucanase, cellobiohydrolase, beta-glucosidase, xylanase, mannanse, .beta.-xylosidase, arabinofuranosidase, and/or oligomerase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts. The invention also provides compositions or products of manufacture comprising mixtures of enzymes comprising at least one enzyme of this invention.

Research Organization:
BP Corporation North America Inc., Houston, TX, (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FC36-03GO13146
Assignee:
BP Corporation North America Inc.
Patent Number(s):
9,175,275
Application Number:
13/751,923
OSTI ID:
1224888
Resource Relation:
Patent File Date: 2013 Jan 28
Country of Publication:
United States
Language:
English

References (60)

Preparation of low alcohol beer patent November 1988
Production of soft paper products from old newspaper patent December 1996
Prehydrolysis of lignocellulose patent January 1998
Process for digesting cellulose containing solid wastes patent January 1998
Glucose and cellobiose tolerant .beta.-glucosidase from Candida peltata patent May 1998
Protein having .alpha.-glucosidase activity, DNA having genetic information thereof, and production of .alpha.-glucosidase patent August 1998
Mobile Bioreactor and Biogenerator patent November 1998
Treatment of animal waste patent September 1999
Coniferin beta-glucosidase cDNA for modifying lignin content in plants patent October 1999
Cloning and amplification of the .beta.-glucosidase gene of Trichoderma reesei patent February 2000
Method of improving pulp freeness using cellulase and pectinase enzymes patent May 2000
Treatment of fabrics patent June 2000
.beta.-glucosidase from filamentous fungi, and uses thereof patent July 2000
Pretreatment process for conversion of cellulose to fuel ethanol patent July 2000
Protein having cellulase activities and process for producing the same patent October 2000
.beta.-glucosidase coding sequences and protein from orpinomyces PC-2 patent February 2001
Methods for deinking and decolorizing printed paper patent June 2001
Method for using a vegetable biomass and a screw press to carry out said method patent June 2001
Process for the production of organic products from diverse biomass sources patent June 2002
Dilute acid/metal salt hydrolysis of lignocellulosics patent July 2002
Cellulase preparation comprising an endoglucanase enzyme patent July 2002
Polypeptide having cellobiohydrolase activity patent May 2003
Phenolic acid esterases, coding sequences and methods patent August 2003
Ethanol production with dilute acid hydrolysis using partially dried lignocellulosics patent December 2003
Endoglucanases and cellulase preparations containing the same patent July 2005
Epoxide hydrolases, nucleic acids encoding them and methods of making and using them patent December 2005
Hybrid enzymes patent October 2006
Expression cloning in filamentous fungi patent May 2007
Thermal tolerant exoglucanase from Acidothermus cellulolyticus patent July 2008
Superactive cellulase formulation using cellobiohydrolase-1 from Penicillium funiculosum patent November 2008
Nucleic acids and proteins and methods for making and using them patent February 2012
Expression of microbial proteins in plants for production of plants with improved properties patent-application December 2003
Thermostable cellulase and methods of use patent-application November 2007
Enzymes for the Treatment of Lignocellulosics, Nucleic Acids Encoding Them and Methods for Making and Using Them patent-application July 2010
Comparison of modular and non-modular xylanases as carrier proteins for the efficient secretion of heterologous proteins from Penicillium funiculosum journal December 2002
Basic local alignment search tool journal October 1990
Biotechnological applications of phage and cell display journal February 2001
Catalytic Plasticity of Fatty Acid Modification Enzymes Underlying Chemical Diversity of Plant Lipids journal November 1998
Practical limits of function prediction journal January 2000
The Cellulosome: The Exocellular Organelle of Clostridium journal October 1993
Rapid Evolution of Reversible Denaturation and Elevated Melting Temperature in a Microbial Haloalkane Dehalogenase journal August 2001
Protein tolerance to random amino acid change journal June 2004
High-Resolution Capillary Gel Electrophoresis of Reducing Oligosaccharides Labeled with 1-Aminopyrene-3,6,8-trisulfonate journal January 1996
Cello-Oligosaccharide Hydrolysis by Cellobiohydrolase II from Trichoderma Reesei. Association and Rate Constants Derived from an Analysis of Progress Curves journal September 1996
GEOLOGY:The Next Oil Crisis Looms Large--and Perhaps Close journal August 1998
OIL OUTLOOK:USGS Optimistic on World Oil Prospects journal July 2000
FUNCTIONAL GENOMICS: Expression Cloning in the Test Tube journal August 1997
Collection, Mapping, and Annotation of Over 28,000 cDNA Clones from japonica Rice journal July 2003
An easy colorimetric assay for screening and qualitative assessment of deiodination and dehalogenation by bacterial cultures journal June 1999
The use of selection in recovery of transgenic targets for mutation analysis journal February 1993
Consolidated bioprocessing of cellulosic biomass: an update journal October 2005
Microbial Cellulose Utilization: Fundamentals and Biotechnology journal September 2002
Crystal structure of the family 7 endoglucanase I (Cel7B) from Humicola insolens at 2.2 Å resolution and identification of the catalytic nucleophile by trapping of the covalent glycosyl-enzyme intermediate journal October 1998
A Novel, High Performance Enzyme for Starch Liquefaction: DISCOVERY AND OPTIMIZATION OF A LOW pH, THERMOSTABLE α-AMYLASE journal May 2002
Structure and mechanism of endo/exocellulase E4 from Thermomonospora fusca journal October 1997
Developments in Directed Evolution for Improving Enzyme Functions journal August 2007
λ ZAP: a bacteriophage λ expression vector with in vivo excision properties journal January 1988
Crystal structure of the catalytic core domain of the family 6 cellobiohydrolase II, Cel6A, from Humicola insolens, at 1.92 Å resolution journal January 1999
Directed evolution of an aspartate aminotransferase with new substrate specificities journal May 1998
A newly described cellulosomal cellobiohydrolase, CelO, from Clostridium thermocellum: investigation of the exo-mode of hydrolysis, and binding capacity to crystalline cellulose journal January 2002