skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets

Journal Article · · eLife
DOI:https://doi.org/10.7554/eLife.07646· OSTI ID:1223571

Sponsoring Organization:
USDOE
Grant/Contract Number:
AC02-76SF00515, DE-AC02-05CH11231, DE-AC02-06CH11357
OSTI ID:
1223571
Alternate ID(s):
OSTI ID: 1223572
Journal Information:
eLife, Journal Name: eLife Vol. 4; ISSN 2050-084X
Publisher:
eLife Sciences Publications, Ltd.Copyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 62 works
Citation information provided by
Web of Science

References (42)

MicroRNAs: Target Recognition and Regulatory Functions journal January 2009
Widespread changes in protein synthesis induced by microRNAs journal July 2008
Overview of the CCP 4 suite and current developments journal March 2011
Principles of MicroRNA–Target Recognition journal February 2005
Gene silencing by microRNAs: contributions of translational repression and mRNA decay journal January 2011
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 journal December 1993
Argonaute2 Is the Catalytic Engine of Mammalian RNAi journal September 2004
The Initial Uridine of Primary piRNAs Does Not Create the Tenth Adenine that Is the Hallmark of Secondary piRNAs journal December 2014
Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors journal January 1994
Features and development of Coot journal March 2010
New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection journal November 2008
MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing journal July 2007
Combinatorial microRNA target predictions journal April 2005
Prediction of Mammalian MicroRNA Targets journal December 2003
Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs journal July 2004
Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets journal January 2005
miRBase: integrating microRNA annotation and deep-sequencing data journal October 2010
An Extensive Class of Small RNAs in Caenorhabditis elegans journal October 2001
The Crystal Structure of Human Argonaute2 journal April 2012
PHENIX: a comprehensive Python-based system for macromolecular structure solution journal January 2010
Development of micro RNA therapeutics is coming of age journal June 2014
The Making of a Slicer: Activation of Human Argonaute-1 journal June 2013
Formation, regulation and evolution of Caenorhabditis elegans 3′UTRs journal November 2010
A Dynamic Search Process Underlies MicroRNA Targeting journal July 2015
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs journal January 2005
Determinants of targeting by endogenous and exogenous microRNAs and siRNAs journal September 2007
Structural basis for microRNA targeting journal October 2014
Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons journal June 2012
An Abundant Class of Tiny RNAs with Probable Regulatory Roles in Caenorhabditis elegans journal October 2001
MicroRNAs in plants journal July 2002
Rapid and specific purification of Argonaute-small RNA complexes from crude cell lysates journal December 2012
Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation journal March 2002
XDS journal January 2010
Blu-Ice and the Distributed Control System : software for data acquisition and instrument control at macromolecular crystallography beamlines journal November 2002
Surface Passivation for Single-molecule Protein Studies journal January 2014
Most mammalian mRNAs are conserved targets of microRNAs journal October 2008
Eukaryote-Specific Insertion Elements Control Human ARGONAUTE Slicer Activity journal June 2013
Crystal structure of trp represser/operator complex at atomic resolution journal September 1988
The impact of microRNAs on protein output journal July 2008
Identification of Novel Genes Coding for Small Expressed RNAs journal October 2001
Specificity of microRNA target selection in translational repression journal March 2004
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans journal December 1993