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Title: An adaptable multiple power source for mass spectrometry and other scientific instruments

Abstract

Power supplies are commonly used in the operation of many types of scientific equipment, including mass spectrometers and ancillary instrumentation. A generic modern mass spectrometer comprises an ionization source, such as electrospray ionization (ESI), ion transfer devices such as ion funnels and multipole ion guides, and ion signal detection apparatus. Very often such platforms include, or are interfaced with ancillary elements in order to manipulate samples before or after ionization. In order to operate such scientific instruments, numerous direct current (DC) channels and radio frequency (RF) signals are required, along with other controls such as temperature regulation. In particular, DC voltages in the range of ±400 V, along with MHz range RF signals with peak-to-peak amplitudes in the hundreds of volts range are commonly used to transfer ionized samples under vacuum. Additionally, an ESI source requires a high voltage (HV) DC source capable of producing several thousand volts and heaters capable of generating temperatures up to 300°C. All of these signals must be properly synchronized and managed in order to carry out ion trapping, accumulation and detection.

Authors:
 [1];  [2];  [1];  [1];  [3];  [4]; ORCiD logo [1];  [1];  [1];  [1];  [1]
  1. Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
  2. GAA Custom Engineering, LLC, Benton City, WA (United States); Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
  3. Hecate Software, Inc., Fort Worth, TX (United States); Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
  4. Photochem Technologies, Athens, GA (United States); Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Publication Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL)
Sponsoring Org.:
USDOE
OSTI Identifier:
1222077
Report Number(s):
PNNL-SA-110063
Journal ID: ISSN 0034-6748; 48691; KP1704020
Grant/Contract Number:  
AC05-76RL01830
Resource Type:
Journal Article: Accepted Manuscript
Journal Name:
Review of Scientific Instruments
Additional Journal Information:
Journal Volume: 86; Journal Issue: 9; Journal ID: ISSN 0034-6748
Publisher:
American Institute of Physics (AIP)
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION; Environmental Molecular Sciences Laboratory

Citation Formats

Lin, Tzu -Yung, Anderson, Gordon A., Norheim, Randolph V., Prost, Spencer A., LaMarche, Brian L., Leach, III, Franklin E., Auberry, Kenneth J., Smith, Richard D., Koppenaal, David W., Robinson, Errol W., and Pasa-Tolic, Ljiljana. An adaptable multiple power source for mass spectrometry and other scientific instruments. United States: N. p., 2015. Web. doi:10.1063/1.4930967.
Lin, Tzu -Yung, Anderson, Gordon A., Norheim, Randolph V., Prost, Spencer A., LaMarche, Brian L., Leach, III, Franklin E., Auberry, Kenneth J., Smith, Richard D., Koppenaal, David W., Robinson, Errol W., & Pasa-Tolic, Ljiljana. An adaptable multiple power source for mass spectrometry and other scientific instruments. United States. doi:10.1063/1.4930967.
Lin, Tzu -Yung, Anderson, Gordon A., Norheim, Randolph V., Prost, Spencer A., LaMarche, Brian L., Leach, III, Franklin E., Auberry, Kenneth J., Smith, Richard D., Koppenaal, David W., Robinson, Errol W., and Pasa-Tolic, Ljiljana. Thu . "An adaptable multiple power source for mass spectrometry and other scientific instruments". United States. doi:10.1063/1.4930967. https://www.osti.gov/servlets/purl/1222077.
@article{osti_1222077,
title = {An adaptable multiple power source for mass spectrometry and other scientific instruments},
author = {Lin, Tzu -Yung and Anderson, Gordon A. and Norheim, Randolph V. and Prost, Spencer A. and LaMarche, Brian L. and Leach, III, Franklin E. and Auberry, Kenneth J. and Smith, Richard D. and Koppenaal, David W. and Robinson, Errol W. and Pasa-Tolic, Ljiljana},
abstractNote = {Power supplies are commonly used in the operation of many types of scientific equipment, including mass spectrometers and ancillary instrumentation. A generic modern mass spectrometer comprises an ionization source, such as electrospray ionization (ESI), ion transfer devices such as ion funnels and multipole ion guides, and ion signal detection apparatus. Very often such platforms include, or are interfaced with ancillary elements in order to manipulate samples before or after ionization. In order to operate such scientific instruments, numerous direct current (DC) channels and radio frequency (RF) signals are required, along with other controls such as temperature regulation. In particular, DC voltages in the range of ±400 V, along with MHz range RF signals with peak-to-peak amplitudes in the hundreds of volts range are commonly used to transfer ionized samples under vacuum. Additionally, an ESI source requires a high voltage (HV) DC source capable of producing several thousand volts and heaters capable of generating temperatures up to 300°C. All of these signals must be properly synchronized and managed in order to carry out ion trapping, accumulation and detection.},
doi = {10.1063/1.4930967},
journal = {Review of Scientific Instruments},
number = 9,
volume = 86,
place = {United States},
year = {Thu Sep 17 00:00:00 EDT 2015},
month = {Thu Sep 17 00:00:00 EDT 2015}
}

Journal Article:
Free Publicly Available Full Text
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Cited by: 2 works
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Works referenced in this record:

The ion funnel: Theory, implementations, and applications
journal, April 2009

  • Kelly, Ryan T.; Tolmachev, Aleksey V.; Page, Jason S.
  • Mass Spectrometry Reviews, Vol. 29, Issue 2, p. 294-312
  • DOI: 10.1002/mas.20232

Experimental Evaluation and Optimization of Structures for Lossless Ion Manipulations for Ion Mobility Spectrometry with Time-of-Flight Mass Spectrometry
journal, September 2014

  • Webb, Ian K.; Garimella, Sandilya V. B.; Tolmachev, Aleksey V.
  • Analytical Chemistry, Vol. 86, Issue 18, p. 9169-9176
  • DOI: 10.1021/ac502055e