Celluloytic enzymes, nucleic acids encoding them and methods for making and using them

Gray, Kevin A.; Zhao, Lishan; Cayouette, Michelle H.

Celluloytic enzymes, nucleic acids encoding them and methods for making and using them

Patent · 08 September 2015

OSTI ID:1214148

Gray, Kevin A.; Zhao, Lishan; Cayouette, Michelle H.

The invention is directed to polypeptides having any cellulolytic activity, e.g., a cellulase activity, e.g., endoglucanase, cellobiohydrolase, beta-glucosidase, xylanase, mannanse, .beta.-xylosidase, arabinofuranosidase, and/or oligomerase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts. The invention also provides compositions or products of manufacture comprising mixtures of enzymes comprising at least one enzyme of this invention.

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Research Organization:: BP Corporation North America Inc., Houston, TX (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: FC36-03GO13146

Assignee:: BP Corporation North America Inc. (Houston, TX)

Patent Number(s):: 9,127,263

Application Number:: 13/354,503

OSTI ID:: 1214148

Country of Publication:: United States

Language:: English

References (28)

Rapid Evolution of Reversible Denaturation and Elevated Melting Temperature in a Microbial Haloalkane Dehalogenase Gray, Kevin A.; Richardson, Toby H.; Kretz, Keith Advanced Synthesis & Catalysis, Vol. 343, Issue 6-7 https://doi.org/10.1002/1615-4169(200108)343:6/7<607::AID-ADSC607>3.0.CO;2-M	journal	August 2001
Cello-Oligosaccharide Hydrolysis by Cellobiohydrolase II from Trichoderma Reesei. Association and Rate Constants Derived from an Analysis of Progress Curves Harjunpaa, Vesa; Teleman, Anita; Koivula, Anu European Journal of Biochemistry, Vol. 240, Issue 3 https://doi.org/10.1111/j.1432-1033.1996.0584h.x	journal	September 1996
Stagonospora avenae Secretes Multiple Enzymes that Hydrolyze Oat Leaf Saponins Morrissey, John P.; Wubben, Jos P.; Osbourn, Anne E. Molecular Plant-Microbe Interactions, Vol. 13, Issue 10 https://doi.org/10.1094/MPMI.2000.13.10.1041	journal	October 2000
Protein tolerance to random amino acid change Guo, H. H.; Choe, J.; Loeb, L. A. Proceedings of the National Academy of Sciences, Vol. 101, Issue 25, p. 9205-9210 https://doi.org/10.1073/pnas.0403255101	journal	June 2004
λ ZAP: a bacteriophage λ expression vector with in vivo excision properties Short, Jay M.; Fernandez, Joseph M.; Sorge, Joseph A. Nucleic Acids Research, Vol. 16, Issue 15 https://doi.org/10.1093/nar/16.15.7583	journal	January 1988
Catalytic Plasticity of Fatty Acid Modification Enzymes Underlying Chemical Diversity of Plant Lipids Broun, Pierre; Shanklin, John; Whittle, Ed Science, Vol. 282, Issue 5392, p. 1315-1317 https://doi.org/10.1126/science.282.5392.1315	journal	November 1998
Microbial Cellulose Utilization: Fundamentals and Biotechnology Lynd, L. R.; Weimer, P. J.; van Zyl, W. H. Microbiology and Molecular Biology Reviews, Vol. 66, Issue 3, p. 506-577 https://doi.org/10.1128/MMBR.66.3.506-577.2002	journal	September 2002
Prediction of protein function from protein sequence and structure Whisstock, James C.; Lesk, Arthur M. Quarterly Reviews of Biophysics, Vol. 36, Issue 3, p. 307-340 https://doi.org/10.1017/S0033583503003901	journal	January 1999
Biotechnological applications of phage and cell display Benhar, Itai Biotechnology Advances, Vol. 19, Issue 1, p. 1-33 https://doi.org/10.1016/S0734-9750(00)00054-9	journal	February 2001
An easy colorimetric assay for screening and qualitative assessment of deiodination and dehalogenation by bacterial cultures Kuritz, T. Letters in Applied Microbiology, Vol. 28, Issue 6 https://doi.org/10.1046/j.1365-2672.1999.00538.x	journal	June 1999
Crystal structure of the catalytic core domain of the family 6 cellobiohydrolase II, Cel6A, from Humicola insolens, at 1.92 Å resolution Varrot, Annabelle; Hastrup, Sven; SchÜLein, Martin Biochemical Journal, Vol. 337, Issue 2 https://doi.org/10.1042/bj3370297	journal	January 1999
Developments in Directed Evolution for Improving Enzyme Functions Sen, S.; Venkata Dasu, V.; Mandal, B. Applied Biochemistry and Biotechnology, Vol. 143, Issue 3, p. 212-223 https://doi.org/10.1007/s12010-007-8003-4	journal	August 2007
GEOLOGY:The Next Oil Crisis Looms Large--and Perhaps Close Kerr, R. A. Science, Vol. 281, Issue 5380 https://doi.org/10.1126/science.281.5380.1128	journal	August 1998
FUNCTIONAL GENOMICS: Expression Cloning in the Test Tube King, R. W. Science, Vol. 277, Issue 5328 https://doi.org/10.1126/science.277.5328.973	journal	August 1997
The Cellulosome: The Exocellular Organelle of Clostridium Felix, C. R.; Ljungdahl, L. G. Annual Review of Microbiology, Vol. 47, Issue 1 https://doi.org/10.1146/annurev.mi.47.100193.004043	journal	October 1993
OIL OUTLOOK:USGS Optimistic on World Oil Prospects Kerr, R. A. Science, Vol. 289, Issue 5477 https://doi.org/10.1126/science.289.5477.237	journal	July 2000
A Novel, High Performance Enzyme for Starch Liquefaction: DISCOVERY AND OPTIMIZATION OF A LOW pH, THERMOSTABLE α-AMYLASE Richardson, Toby H.; Tan, Xuqiu; Frey, Gerhard Journal of Biological Chemistry, Vol. 277, Issue 29 https://doi.org/10.1074/jbc.M203183200	journal	May 2002
Structure and mechanism of endo/exocellulase E4 from Thermomonospora fusca Sakon, Joshua; Irwin, Diana; Wilson, David B. Nature Structural Biology, Vol. 4, Issue 10 https://doi.org/10.1038/nsb1097-810	journal	October 1997
High-Resolution Capillary Gel Electrophoresis of Reducing Oligosaccharides Labeled with 1-Aminopyrene-3,6,8-trisulfonate Guttman, András; Chen, Fu-Tai A.; Evangelista, Ramon A. Analytical Biochemistry, Vol. 233, Issue 2 https://doi.org/10.1006/abio.1996.0034	journal	January 1996
Collection, Mapping, and Annotation of Over 28,000 cDNA Clones from japonica Rice Kikuchi, S. Science, Vol. 301, Issue 5631 https://doi.org/10.1126/science.1081288	journal	July 2003
Cellulase for commodity products from cellulosic biomass Himmel, Michael E.; Ruth, Mark F.; Wyman, Charles E. Current Opinion in Biotechnology, Vol. 10, Issue 4, p. 358-364 https://doi.org/10.1016/S0958-1669(99)80065-2	journal	August 1999
Comparison of modular and non-modular xylanases as carrier proteins for the efficient secretion of heterologous proteins from Penicillium funiculosum Alcocer, M. J. C.; Furniss, C. S. M.; Kroon, P. A. Applied Microbiology and Biotechnology, Vol. 60, Issue 6 https://doi.org/10.1007/s00253-002-1184-4	journal	December 2002
Directed evolution of an aspartate aminotransferase with new substrate specificities Yano, T.; Oue, S.; Kagamiyama, H. Proceedings of the National Academy of Sciences, Vol. 95, Issue 10 https://doi.org/10.1073/pnas.95.10.5511	journal	May 1998
The use of selection in recovery of transgenic targets for mutation analysis Lundberg, Kelly S.; Kretz, Patricia L.; Scott Provost, G. Mutation Research Letters, Vol. 301, Issue 2, p. 99-105 https://doi.org/10.1016/0165-7992(93)90031-P	journal	February 1993
Crystal structure of the family 7 endoglucanase I (Cel7B) from Humicola insolens at 2.2 Å resolution and identification of the catalytic nucleophile by trapping of the covalent glycosyl-enzyme intermediate Mackenzie, Lloyd F.; Sulzenbacher, Gerlind; Divne, Christina Biochemical Journal, Vol. 335, Issue 2 https://doi.org/10.1042/bj3350409	journal	October 1998
A newly described cellulosomal cellobiohydrolase, CelO, from Clostridium thermocellum: investigation of the exo-mode of hydrolysis, and binding capacity to crystalline cellulose Schwarz, Wolfgang H.; Velikodvorskaya, Galina A.; Zverlov, Vladimir V. Microbiology, Vol. 148, Issue 1 https://doi.org/10.1099/00221287-148-1-247	journal	January 2002
Basic local alignment search tool Altschul, Stephen F.; Gish, Warren; Miller, Webb Journal of Molecular Biology, Vol. 215, Issue 3, p. 403-410 https://doi.org/10.1016/S0022-2836(05)80360-2	journal	October 1990
Practical limits of function prediction Devos, Damien; Valencia, Alfonso Proteins: Structure, Function, and Genetics, Vol. 41, Issue 1, p. 98-107 https://doi.org/10.1002/1097-0134(20001001)41:1<98::AID-PROT120>3.0.CO;2-S	journal	January 2000

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