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Genetic barcodes

Patent ·
OSTI ID:1207279
Herein are described multicolor FISH probe sets termed "genetic barcodes" targeting several cancer or disease-related loci to assess gene rearrangements and copy number changes in tumor cells. Two, three or more different fluorophores are used to detect the genetic barcode sections thus permitting unique labeling and multilocus analysis in individual cell nuclei. Gene specific barcodes can be generated and combined to provide both numerical and structural genetic information for these and other pertinent disease associated genes.
Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC02-05CH11231;
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
9,096,902
Application Number:
13/849,452
OSTI ID:
1207279
Country of Publication:
United States
Language:
English

References (20)

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