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Title: Methods and kits for predicting a response to an erythropoietic agent

Abstract

Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent. Kits for predicting a response to an erythropoietic agent are further provided and include one or more antibodies, or fragments thereof, that specifically recognize a peptide of SEQ ID NOS: 1-17.

Inventors:
; ; ;
Publication Date:
Research Org.:
University of Louisville Research Foundation, Inc., Louisville, KY (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1184560
Patent Number(s):
9,057,731
Application Number:
13/167,478
Assignee:
University of Louisville Research Foundation, Inc. (Louisville, KY) CHO
DOE Contract Number:  
FG02-05ER64060
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Merchant, Michael L., Klein, Jon B., Brier, Michael E., and Gaweda, Adam E. Methods and kits for predicting a response to an erythropoietic agent. United States: N. p., 2015. Web.
Merchant, Michael L., Klein, Jon B., Brier, Michael E., & Gaweda, Adam E. Methods and kits for predicting a response to an erythropoietic agent. United States.
Merchant, Michael L., Klein, Jon B., Brier, Michael E., and Gaweda, Adam E. Tue . "Methods and kits for predicting a response to an erythropoietic agent". United States. doi:. https://www.osti.gov/servlets/purl/1184560.
@article{osti_1184560,
title = {Methods and kits for predicting a response to an erythropoietic agent},
author = {Merchant, Michael L. and Klein, Jon B. and Brier, Michael E. and Gaweda, Adam E.},
abstractNote = {Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent. Kits for predicting a response to an erythropoietic agent are further provided and include one or more antibodies, or fragments thereof, that specifically recognize a peptide of SEQ ID NOS: 1-17.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 16 00:00:00 EDT 2015},
month = {Tue Jun 16 00:00:00 EDT 2015}
}

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Works referenced in this record:

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Interaction of a novel cysteine and histidine-rich cytoplasmic protein with galectin-3 in a carbohydrate-independent manner
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