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Title: Microfluidic ultrasonic particle separators with engineered node locations and geometries

Abstract

An ultrasonic microfluidic system includes a separation channel for conveying a sample fluid containing small particles and large particles, flowing substantially parallel, adjacent to a recovery fluid, with which it is in contact. An acoustic transducer produces an ultrasound standing wave, that generates a pressure field having at least one node of minimum, pressure amplitude. An acoustic extension structure is located proximate to said separation channel for positioning said acoustic node off center in said acoustic area and concentrating the large particles in said recovery fluid stream.

Inventors:
; ; ; ; ; ; ; ;
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1177131
Patent Number(s):
8,991,614
Application Number:
14/246,981
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA) LSO
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Resource Relation:
Patent File Date: 2014 Apr 07
Country of Publication:
United States
Language:
English
Subject:
42 ENGINEERING; 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS

Citation Formats

Rose, Klint A, Fisher, Karl A, Wajda, Douglas A, Mariella, Jr., Raymond P, Bailey, Christopher, Dehlinger, Dietrich, Shusteff, Maxim, Jung, Byoungsok, and Ness, Kevin D. Microfluidic ultrasonic particle separators with engineered node locations and geometries. United States: N. p., 2015. Web.
Rose, Klint A, Fisher, Karl A, Wajda, Douglas A, Mariella, Jr., Raymond P, Bailey, Christopher, Dehlinger, Dietrich, Shusteff, Maxim, Jung, Byoungsok, & Ness, Kevin D. Microfluidic ultrasonic particle separators with engineered node locations and geometries. United States.
Rose, Klint A, Fisher, Karl A, Wajda, Douglas A, Mariella, Jr., Raymond P, Bailey, Christopher, Dehlinger, Dietrich, Shusteff, Maxim, Jung, Byoungsok, and Ness, Kevin D. Tue . "Microfluidic ultrasonic particle separators with engineered node locations and geometries". United States. doi:. https://www.osti.gov/servlets/purl/1177131.
@article{osti_1177131,
title = {Microfluidic ultrasonic particle separators with engineered node locations and geometries},
author = {Rose, Klint A and Fisher, Karl A and Wajda, Douglas A and Mariella, Jr., Raymond P and Bailey, Christopher and Dehlinger, Dietrich and Shusteff, Maxim and Jung, Byoungsok and Ness, Kevin D},
abstractNote = {An ultrasonic microfluidic system includes a separation channel for conveying a sample fluid containing small particles and large particles, flowing substantially parallel, adjacent to a recovery fluid, with which it is in contact. An acoustic transducer produces an ultrasound standing wave, that generates a pressure field having at least one node of minimum, pressure amplitude. An acoustic extension structure is located proximate to said separation channel for positioning said acoustic node off center in said acoustic area and concentrating the large particles in said recovery fluid stream.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 31 00:00:00 EDT 2015},
month = {Tue Mar 31 00:00:00 EDT 2015}
}

Patent:

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Works referenced in this record:

Micro-manipulation of small particles by node position control of an ultrasonic standing wave
journal, May 2002


Multi-modal particle manipulator to enhance bead-based bioassays
journal, February 2010